Detalhe da pesquisa
1.
DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease.
Proc Natl Acad Sci U S A
; 114(36): E7526-E7535, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827334
2.
Polycomb eviction as a new distant enhancer function.
Genes Dev
; 25(15): 1583-8, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21828268
3.
Genomically humanized mice: technologies and promises.
Nat Rev Genet
; 13(1): 14-20, 2011 Dec 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22179716
4.
An interspecies analysis reveals a key role for unmethylated CpG dinucleotides in vertebrate Polycomb complex recruitment.
EMBO J
; 31(2): 317-29, 2012 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-22056776
5.
Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.
BMC Dev Biol
; 15: 35, 2015 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-26453549
6.
Hes1 desynchronizes differentiation of pluripotent cells by modulating STAT3 activity.
Stem Cells
; 31(8): 1511-22, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23649667
7.
Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration.
Nature
; 453(7195): 662-6, 2008 May 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-18449193
8.
Transposon-mediated BAC transgenesis in human ES cells.
Nucleic Acids Res
; 40(19): e150, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22753106
9.
Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence.
PLoS Genet
; 7(11): e1002348, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-22072979
10.
Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.
Nature
; 441(7091): 366-70, 2006 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16625210
11.
Chromosome looping at the human alpha-globin locus is mediated via the major upstream regulatory element (HS -40).
Blood
; 114(19): 4253-60, 2009 Nov 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-19696202
12.
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.
Proc Natl Acad Sci U S A
; 105(24): 8292-7, 2008 Jun 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-18544649
13.
Introducing Point Mutations into Human Pluripotent Stem Cells using Seamless Genome Editing.
J Vis Exp
; (159)2020 05 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32449724
14.
Neurofascins are required to establish axonal domains for saltatory conduction.
Neuron
; 48(5): 737-42, 2005 Dec 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-16337912
15.
Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues.
PLoS Genet
; 2(4): e58, 2006 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-16628246
16.
Multiomics Analyses of HNF4α Protein Domain Function during Human Pluripotent Stem Cell Differentiation.
iScience
; 16: 206-217, 2019 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-31185456
17.
A Human IPS Model Implicates Embryonic B-Myeloid Fate Restriction as Developmental Susceptibility to B Acute Lymphoblastic Leukemia-Associated ETV6-RUNX1.
Dev Cell
; 44(3): 362-377.e7, 2018 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29290585
18.
Identification and Single-Cell Functional Characterization of an Endodermally Biased Pluripotent Substate in Human Embryonic Stem Cells.
Stem Cell Reports
; 10(6): 1895-1907, 2018 06 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29779895
19.
Essential role for proteinase-activated receptor-2 in arthritis.
J Clin Invest
; 111(1): 35-41, 2003 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-12511586
20.
Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles.
Nat Biotechnol
; 21(4): 443-7, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12627172