Detalhe da pesquisa
1.
Synthesis and biological evaluation of 6-phenylpurine linked hydroxamates as novel histone deacetylase inhibitors.
Bioorg Chem
; 98: 103724, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32171983
2.
Structure and ligand-based design of mTOR and PI3-kinase inhibitors leading to the clinical candidates VS-5584 (SB2343) and SB2602.
J Chem Inf Model
; 54(11): 3238-50, 2014 Nov 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25317974
3.
Structure-based design of PDK1 inhibitors.
Bioorg Med Chem Lett
; 22(1): 305-7, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22119465
4.
Structure-based optimization of morpholino-triazines as PI3K and mTOR inhibitors.
Bioorg Med Chem Lett
; 22(2): 1009-13, 2012 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22197143
5.
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1.
Bioorg Med Chem Lett
; 22(8): 2880-4, 2012 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437109
6.
Design, Synthesis, and Preclinical Evaluation of Fused Pyrimidine-Based Hydroxamates for the Treatment of Hepatocellular Carcinoma.
J Med Chem
; 61(4): 1552-1575, 2018 02 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29360358