Detalhe da pesquisa
1.
Repeat expansions confer WRN dependence in microsatellite-unstable cancers.
Nature
; 586(7828): 292-298, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32999459
2.
The RNA-binding motif protein 14 regulates telomere integrity at the interface of TERRA and telomeric R-loops.
Nucleic Acids Res
; 51(22): 12242-12260, 2023 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-37930826
3.
Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions.
J Biol Chem
; 299(3): 102980, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36739951
4.
Biochemical analysis of DNA synthesis blockage by G-quadruplex structure and bypass facilitated by a G4-resolving helicase.
Methods
; 204: 207-214, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34929333
5.
Mitochondrial genetic variation is enriched in G-quadruplex regions that stall DNA synthesis in vitro.
Hum Mol Genet
; 29(8): 1292-1309, 2020 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32191790
6.
FANCJ compensates for RAP80 deficiency and suppresses genomic instability induced by interstrand cross-links.
Nucleic Acids Res
; 48(16): 9161-9180, 2020 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32797166
7.
A minimal threshold of FANCJ helicase activity is required for its response to replication stress or double-strand break repair.
Nucleic Acids Res
; 46(12): 6238-6256, 2018 07 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29788478
8.
Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
J Biol Chem
; 291(27): 14324-14339, 2016 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226550
9.
Biochemical and cell biological assays to identify and characterize DNA helicase inhibitors.
Methods
; 108: 130-41, 2016 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27064001
10.
Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.
J Biol Chem
; 289(29): 19928-41, 2014 Jul 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-24895130
11.
DNA sequences proximal to human mitochondrial DNA deletion breakpoints prevalent in human disease form G-quadruplexes, a class of DNA structures inefficiently unwound by the mitochondrial replicative Twinkle helicase.
J Biol Chem
; 289(43): 29975-93, 2014 Oct 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25193669
12.
Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome.
EMBO J
; 30(4): 692-705, 2011 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-21240188
13.
Molecular functions and cellular roles of the ChlR1 (DDX11) helicase defective in the rare cohesinopathy Warsaw breakage syndrome.
Cell Mol Life Sci
; 71(14): 2625-39, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24487782
14.
Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability.
J Biol Chem
; 288(39): 28217-29, 2013 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-23935105
15.
Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress.
Proc Natl Acad Sci U S A
; 108(4): 1525-30, 2011 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21220316
16.
Purification and biochemical characterization of the G4 resolvase and DNA helicase FANCJ.
Methods Enzymol
; 695: 1-27, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38521581
17.
Identification and biochemical characterization of a novel mutation in DDX11 causing Warsaw breakage syndrome.
Hum Mutat
; 34(1): 103-7, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23033317
18.
Biochemical characterization of Warsaw breakage syndrome helicase.
J Biol Chem
; 287(2): 1007-21, 2012 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-22102414
19.
The Q motif of Fanconi anemia group J protein (FANCJ) DNA helicase regulates its dimerization, DNA binding, and DNA repair function.
J Biol Chem
; 287(26): 21699-716, 2012 Jun 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22582397
20.
DNA repair and replication fork helicases are differentially affected by alkyl phosphotriester lesion.
J Biol Chem
; 287(23): 19188-98, 2012 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22500020