Detalhe da pesquisa
1.
Discovery of a structural class of antibiotics with explainable deep learning.
Nature
; 626(7997): 177-185, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38123686
2.
Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology.
Proc Natl Acad Sci U S A
; 113(49): E7880-E7889, 2016 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27864515
3.
Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA-Encoded Chemical Library.
Chembiochem
; 18(9): 864-871, 2017 05 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28056160
4.
Corrigendum: Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNAEncoded Chemical Library.
Chembiochem
; 18(24): 2441, 2017 12 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29239533
5.
Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett
; 8(2): 239-244, 2017 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28197319
6.
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors".
ACS Med Chem Lett
; 8(11): 1204, 2017 11 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-29152055
7.
Isoform-Selective ATAD2 Chemical Probe with Novel Chemical Structure and Unusual Mode of Action.
ACS Chem Biol
; 12(11): 2730-2736, 2017 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-29043777
8.
Discovery of Clinical Candidate 1-{[(2S,3S,4S)-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design.
J Med Chem
; 60(13): 5521-5542, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28498658
9.
Overview of Recent Progress in Protein-Expression Technologies for Small-Molecule Screening.
J Biomol Screen
; 19(7): 1000-13, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24525871
10.
Fragment-based screen against HIV protease.
Chem Biol Drug Des
; 75(3): 257-68, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20659109