Detalhe da pesquisa
1.
Synthesis, Biological Evaluation, and Molecular Modeling Studies of Chiral Chloroquine Analogues as Antimalarial Agents.
Antimicrob Agents Chemother
; 62(12)2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30224532
2.
Design, synthesis and antiplasmodial activity of novel imidazole derivatives based on 7-chloro-4-aminoquinoline.
Bioorg Chem
; 80: 204-211, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-29940342
3.
Investigating Pharmacological Targeting of G-Quadruplexes in the Human Malaria Parasite.
Biochemistry
; 56(51): 6691-6699, 2017 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29182860
4.
Synthesis and Evaluation of Chirally Defined Side Chain Variants of 7-Chloro-4-Aminoquinoline To Overcome Drug Resistance in Malaria Chemotherapy.
Antimicrob Agents Chemother
; 61(3)2017 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27956423
5.
Antimalarial activity of novel 4-aminoquinolines active against drug resistant strains.
Bioorg Chem
; 70: 74-85, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908538
6.
In vitro susceptibility of Indian Plasmodium falciparum isolates to different antimalarial drugs & antibiotics.
Indian J Med Res
; 146(5): 622-628, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29512604
7.
Correlation between in vitro and in vivo antimalarial activity of compounds using CQ-sensitive and CQ-resistant strains of Plasmodium falciparum and CQ-resistant strain of P. yoelii.
Parasitol Res
; 116(7): 1849-1854, 2017 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-28502016
8.
Design, Synthesis, and Biological Evaluation of Novel 1,2,4-Trioxanes as Potential Antimalarial Agents.
Arch Pharm (Weinheim)
; 350(3-4)2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28207169
9.
Synthesis of S-(-)-5,6-Dihydrocanthin-4-ones via a Triple Cooperative Catalysis-Mediated Domino Reaction.
J Org Chem
; 81(11): 4751-61, 2016 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-27159615
10.
Pyrrolidine-Acridine hybrid in Artemisinin-based combination: a pharmacodynamic study.
Parasitology
; 143(11): 1421-32, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27230403
11.
Synthesis, in vitro and in silico antimalarial activity of 7-chloroquinoline and 4H-chromene conjugates.
Bioorg Med Chem Lett
; 25(20): 4657-63, 2015 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26338359
12.
In Silico Exploration for New Antimalarials: Arylsulfonyloxy Acetimidamides as Prospective Agents.
J Chem Inf Model
; 55(8): 1708-19, 2015 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-26237069
13.
Sulfur mobilization for Fe-S cluster assembly by the essential SUF pathway in the Plasmodium falciparum apicoplast and its inhibition.
Antimicrob Agents Chemother
; 58(6): 3389-98, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24709262
14.
Synthesis and evaluation of new diaryl ether and quinoline hybrids as potential antiplasmodial and antimicrobial agents.
Bioorg Med Chem Lett
; 24(7): 1719-23, 2014 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24630564
15.
Antiplasmodial activity of new 4-aminoquinoline derivatives against chloroquine resistant strain.
Bioorg Med Chem
; 22(14): 3573-86, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24906512
16.
Synthesis of chiral chloroquine and its analogues as antimalarial agents.
Bioorg Med Chem
; 22(21): 5950-60, 2014 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25284252
17.
A natural product inspired hybrid approach towards the synthesis of novel pentamidine based scaffolds as potential anti-parasitic agents.
Bioorg Med Chem Lett
; 23(1): 291-6, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23182089
18.
Design, synthesis of 4-aminoquinoline-derived thiazolidines and their antimalarial activity and heme polymerization inhibition studies.
J Enzyme Inhib Med Chem
; 28(3): 619-26, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22432870
19.
Design and synthesis of 3-[(7-chloro-1-oxidoquinolin-4-ylamino)alkyl]-1,3-thiazolidin-4-ones as antimalarial agents.
J Enzyme Inhib Med Chem
; 28(5): 1048-53, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22957722
20.
Coumarin-trioxane hybrids: synthesis and evaluation as a new class of antimalarial scaffolds.
Bioorg Med Chem Lett
; 22(12): 3926-30, 2012 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22607674