Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Cofactorless oxygenases guide anthraquinone-fused enediyne biosynthesis.

Gui, Chun; Kalkreuter, Edward; Liu, Yu-Chen; Li, Gengnan; Steele, Andrew D; Yang, Dong; Chang, Changsoo; Shen, Ben.

Nat Chem Biol ; 20(2): 243-250, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37945897

2.

Discrete Acyltransferases and Thioesterases in Iso-Migrastatin and Lactimidomycin Biosynthesis.

Steele, Andrew D; Jiang, Hui; Pan, Guohui; Lim, Si-Kyu; Kalkreuter, Edward; Kwong, Thomas; Ju, Jianhua; Rajski, Scott; Shen, Ben.

Biochemistry ; 2024 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-38345531

3.

Prion topology and toxicity.

Aguzzi, Adriano; Steele, Andrew D.

Cell ; 137(6): 994-6, 2009 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-19524502

4.

Biochemical and Structural Studies of the Carminomycin 4-O-Methyltransferase DnrK.

Jalali, Elnaz; Wang, Fengbin; Overbay, Brooke R; Miller, Mitchell D; Shaaban, Khaled A; Ponomareva, Larissa V; Ye, Qing; Saghaeiannejad-Esfahani, Hoda; Bhardwaj, Minakshi; Steele, Andrew D; Teijaro, Christiana N; Shen, Ben; Van Lanen, Steven G; She, Qing-Bai; Voss, S Randal; Phillips, George N; Thorson, Jon S.

J Nat Prod ; 87(4): 798-809, 2024 Apr 26.

Artigo em Inglês | MEDLINE | ID: mdl-38412432

5.

A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim, Wooseong; Zhu, Wenpeng; Hendricks, Gabriel Lambert; Van Tyne, Daria; Steele, Andrew D; Keohane, Colleen E; Fricke, Nico; Conery, Annie L; Shen, Steven; Pan, Wen; Lee, Kiho; Rajamuthiah, Rajmohan; Fuchs, Beth Burgwyn; Vlahovska, Petia M; Wuest, William M; Gilmore, Michael S; Gao, Huajian; Ausubel, Frederick M; Mylonakis, Eleftherios.

Nature ; 556(7699): 103-107, 2018 04 05.

Artigo em Inglês | MEDLINE | ID: mdl-29590091

6.

Biological Evaluation of the Antibacterial Retinoid CD437 in Cutibacterium acnes Infection.

Huang, Xiao-Wen; Pan, Wen; Zhong, Mei-Zhen; Chhonker, Yashpal Singh; Steele, Andrew D; Keohane, Colleen E; Mishra, Biswajit; Felix Raj Lucas, Lewis Oscar; Murry, Daryl J; Ausubel, Frederick M; Wuest, William M; Li, Chang-Xing; Mylonakis, Eleftherios.

Antimicrob Agents Chemother ; 67(4): e0167922, 2023 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-36943064

7.

A selective membrane-targeting repurposed antibiotic with activity against persistent methicillin-resistant Staphylococcus aureus.

Kim, Wooseong; Zou, Guijin; Hari, Taylor P A; Wilt, Ingrid K; Zhu, Wenpeng; Galle, Nicolas; Faizi, Hammad A; Hendricks, Gabriel L; Tori, Katerina; Pan, Wen; Huang, Xiaowen; Steele, Andrew D; Csatary, Erika E; Dekarske, Madeline M; Rosen, Jake L; Ribeiro, Noelly de Queiroz; Lee, Kiho; Port, Jenna; Fuchs, Beth Burgwyn; Vlahovska, Petia M; Wuest, William M; Gao, Huajian; Ausubel, Frederick M; Mylonakis, Eleftherios.

Proc Natl Acad Sci U S A ; 116(33): 16529-16534, 2019 08 13.

Artigo em Inglês | MEDLINE | ID: mdl-31358625

8.

Leveraging a large microbial strain collection for natural product discovery.

Steele, Andrew D; Teijaro, Christiana N; Yang, Dong; Shen, Ben.

J Biol Chem ; 294(45): 16567-16576, 2019 11 08.

Artigo em Inglês | MEDLINE | ID: mdl-31570525

9.

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Keohane, Colleen E; Steele, Andrew D; Fetzer, Christian; Khowsathit, Jittasak; Van Tyne, Daria; Moynié, Lucile; Gilmore, Michael S; Karanicolas, John; Sieber, Stephan A; Wuest, William M.

J Am Chem Soc ; 140(5): 1774-1782, 2018 02 07.

Artigo em Inglês | MEDLINE | ID: mdl-29300464

10.

Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity.

Steele, Andrew D; Keohane, Colleen E; Knouse, Kyle W; Rossiter, Sean E; Williams, Sierra J; Wuest, William M.

J Am Chem Soc ; 138(18): 5833-6, 2016 05 11.

Artigo em Inglês | MEDLINE | ID: mdl-27096543

11.

Total synthesis and biological investigation of (-)-promysalin.

Steele, Andrew D; Knouse, Kyle W; Keohane, Colleen E; Wuest, William M.

J Am Chem Soc ; 137(23): 7314-7, 2015 Jun 17.

Artigo em Inglês | MEDLINE | ID: mdl-26024439

12.

The Natural Products Discovery Center: Release of the First 8490 Sequenced Strains for Exploring Actinobacteria Biosynthetic Diversity.

Kalkreuter, Edward; Kautsar, Satria A; Yang, Dong; Bader, Chantal D; Teijaro, Christiana N; Fluegel, Lucas L; Davis, Christina M; Simpson, Johnathon R; Lauterbach, Lukas; Steele, Andrew D; Gui, Chun; Meng, Song; Li, Gengnan; Viehrig, Konrad; Ye, Fei; Su, Ping; Kiefer, Alexander F; Nichols, Angela; Cepeda, Alexis J; Yan, Wei; Fan, Boyi; Jiang, Yanlong; Adhikari, Ajeeth; Zheng, Cheng-Jian; Schuster, Layla; Cowan, Tyler M; Smanski, Michael J; Chevrette, Marc G; de Carvalho, Luiz P S; Shen, Ben.

bioRxiv ; 2024 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-38168313

13.

The many facets of sulfur incorporation in natural product biosynthesis.

Steele, Andrew D; Kiefer, Alexander F; Shen, Ben.

Curr Opin Chem Biol ; 76: 102366, 2023 10.

Artigo em Inglês | MEDLINE | ID: mdl-37451204

14.

Application of a Biocatalytic Strategy for the Preparation of Tiancimycin-Based Antibody-Drug Conjugates Revealing Key Insights into Structure-Activity Relationships.

Steele, Andrew D; Kiefer, Alexander F; Hwang, Dobeen; Yang, Dong; Teijaro, Christiana N; Adhikari, Ajeeth; Rader, Christoph; Shen, Ben.

J Med Chem ; 66(2): 1562-1573, 2023 01 26.

Artigo em Inglês | MEDLINE | ID: mdl-36599039

15.

Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction.

Carlisle, Holly J; Luong, Tinh N; Medina-Marino, Andrew; Schenker, Leslie; Khorosheva, Eugenia; Indersmitten, Tim; Gunapala, Keith M; Steele, Andrew D; O'Dell, Thomas J; Patterson, Paul H; Kennedy, Mary B.

J Neurosci ; 31(45): 16194-207, 2011 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-22072671

16.

Studying food entrainment: Models, methods, and musings.

Trzeciak, Jacqueline R; Steele, Andrew D.

Front Nutr ; 9: 998331, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36211505

17.

Dopamine systems and biological rhythms: Let's get a move on.

Tang, Qijun; Assali, Dina R; Güler, Ali D; Steele, Andrew D.

Front Integr Neurosci ; 16: 957193, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-35965599

18.

Mice hypomorphic for Pitx3 show robust entrainment of circadian behavioral and metabolic rhythms to scheduled feeding.

Scarpa, Lori L; Wanken, Brad; Smidt, Marten; Mistlberger, Ralph E; Steele, Andrew D.

Cell Rep ; 38(2): 109865, 2022 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-35021098

19.

Cholinergic modulation of locomotion and striatal dopamine release is mediated by alpha6alpha4* nicotinic acetylcholine receptors.

Drenan, Ryan M; Grady, Sharon R; Steele, Andrew D; McKinney, Sheri; Patzlaff, Natalie E; McIntosh, J Michael; Marks, Michael J; Miwa, Julie M; Lester, Henry A.

J Neurosci ; 30(29): 9877-89, 2010 Jul 21.

Artigo em Inglês | MEDLINE | ID: mdl-20660270

20.

Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.

Steele, Andrew D; Hutter, Gregor; Jackson, Walker S; Heppner, Frank L; Borkowski, Andrew W; King, Oliver D; Raymond, Gregory J; Aguzzi, Adriano; Lindquist, Susan.

Proc Natl Acad Sci U S A ; 105(36): 13626-31, 2008 Sep 09.

Artigo em Inglês | MEDLINE | ID: mdl-18757733

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