Detalhe da pesquisa
1.
Systemic Metabolite Changes in Wild-type C57BL/6 Mice Fed Black Raspberries.
Nutr Cancer
; 69(2): 299-306, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28094560
2.
Black raspberries suppress colonic adenoma development in ApcMin/+ mice: relation to metabolite profiles.
Carcinogenesis
; 36(10): 1245-53, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26246425
3.
Stabilization of Ostwald ripening in low molecular weight amino lipid nanoparticles for systemic delivery of siRNA therapeutics.
Mol Pharm
; 11(11): 4143-53, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25317715
4.
Pyridyl aminothiazoles as potent Chk1 inhibitors: optimization of cellular activity.
Bioorg Med Chem Lett
; 22(7): 2613-9, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22365762
5.
Pyridyl aminothiazoles as potent inhibitors of Chk1 with slow dissociation rates.
Bioorg Med Chem Lett
; 22(7): 2609-12, 2012 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22374217
6.
Evaluation of efficacy, biodistribution, and inflammation for a potent siRNA nanoparticle: effect of dexamethasone co-treatment.
Mol Ther
; 18(1): 171-80, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19738601
7.
Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension.
PLoS One
; 12(11): e0187729, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-29121091
8.
Replicated evidence for aminoacylase 3 and nephrin gene variations to predict antihypertensive drug responses.
Pharmacogenomics
; 18(5): 445-458, 2017 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-28353407
9.
The Ephrin-A1/EPHA2 Signaling Axis Regulates Glutamine Metabolism in HER2-Positive Breast Cancer.
Cancer Res
; 76(7): 1825-36, 2016 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26833123
10.
Metabolomics and its Application to the Development of Clinical Laboratory Tests for Prostate Cancer.
EJIFCC
; 26(2): 92-104, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-27683485
11.
Beneficial Regulation of Metabolic Profiles by Black Raspberries in Human Colorectal Cancer Patients.
Cancer Prev Res (Phila)
; 8(8): 743-50, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26054356
12.
Dipeptide species regulate p38MAPK-Smad3 signalling to maintain chronic myelogenous leukaemia stem cells.
Nat Commun
; 6: 8039, 2015 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26289811
13.
Bladder cancer biomarker discovery using global metabolomic profiling of urine.
PLoS One
; 9(12): e115870, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25541698
14.
Optimization of a pyrazoloquinolinone class of Chk1 kinase inhibitors.
Bioorg Med Chem Lett
; 17(21): 5989-94, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17804227
15.
3-(Indol-2-yl)indazoles as Chek1 kinase inhibitors: Optimization of potency and selectivity via substitution at C6.
Bioorg Med Chem Lett
; 16(23): 6049-53, 2006 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16978863
16.
Biochemical and structural characterization of a novel class of inhibitors of the type 1 insulin-like growth factor and insulin receptor kinases.
Biochemistry
; 44(27): 9430-40, 2005 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-15996097
17.
Crystal structure of the Apo, unactivated insulin-like growth factor-1 receptor kinase. Implication for inhibitor specificity.
J Biol Chem
; 277(41): 38797-802, 2002 Oct 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-12138114