Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Allosteric activation of functionally asymmetric RAF kinase dimers.

Hu, Jiancheng; Stites, Edward C; Yu, Haiyang; Germino, Elizabeth A; Meharena, Hiruy S; Stork, Philip J S; Kornev, Alexandr P; Taylor, Susan S; Shaw, Andrey S.

Cell ; 154(5): 1036-1046, 2013 Aug 29.

Artigo em Inglês | MEDLINE | ID: mdl-23993095

2.

Local and dynamic regulation of neuronal glycolysis in vivo.

Wolfe, Aaron D; Koberstein, John N; Smith, Chadwick B; Stewart, Melissa L; Gonzalez, Ian J; Hammarlund, Marc; Hyman, Anthony A; Stork, Philip J S; Goodman, Richard H; Colón-Ramos, Daniel A.

Proc Natl Acad Sci U S A ; 121(3): e2314699121, 2024 Jan 16.

Artigo em Inglês | MEDLINE | ID: mdl-38198527

3.

Monitoring glycolytic dynamics in single cells using a fluorescent biosensor for fructose 1,6-bisphosphate.

Koberstein, John N; Stewart, Melissa L; Smith, Chadwick B; Tarasov, Andrei I; Ashcroft, Frances M; Stork, Philip J S; Goodman, Richard H.

Proc Natl Acad Sci U S A ; 119(31): e2204407119, 2022 08 02.

Artigo em Inglês | MEDLINE | ID: mdl-35881794

4.

Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP.

Takahashi, Maho; Li, Yanping; Dillon, Tara J; Stork, Philip J S.

J Biol Chem ; 292(4): 1449-1461, 2017 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-28003362

5.

Proceedings of the fifth international RASopathies symposium: When development and cancer intersect.

Rauen, Katherine A; Schoyer, Lisa; Schill, Lisa; Stronach, Beth; Albeck, John; Andresen, Brage S; Cavé, Hélène; Ellis, Michelle; Fruchtman, Steven M; Gelb, Bruce D; Gibson, Christopher C; Gripp, Karen; Hefner, Erin; Huang, William Y C; Itkin, Maxim; Kerr, Bronwyn; Linardic, Corinne M; McMahon, Martin; Oberlander, Beverly; Perlstein, Ethan; Ratner, Nancy; Rogers, Leslie; Schenck, Annette; Shankar, Suma; Shvartsman, Stanislav; Stevenson, David A; Stites, Edward C; Stork, Philip J S; Sun, Cheng; Therrien, Marc; Ullian, Erik M; Widemann, Brigitte C; Yeh, Erika; Zampino, Giuseppe; Zenker, Martin; Timmer, William; McCormick, Frank.

Am J Med Genet A ; 176(12): 2924-2929, 2018 12.

Artigo em Inglês | MEDLINE | ID: mdl-30302932

6.

Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP.

Li, Yanping; Dillon, Tara J; Takahashi, Maho; Earley, Keith T; Stork, Philip J S.

J Biol Chem ; 291(41): 21584-21595, 2016 Oct 07.

Artigo em Inglês | MEDLINE | ID: mdl-27531745

7.

N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence.

Wang, Zhiping; Liu, Yuangang; Takahashi, Maho; Van Hook, Kathryn; Kampa-Schittenhelm, Kerstin M; Sheppard, Brett C; Sears, Rosalie C; Stork, Philip J S; Lopez, Charles D.

Proc Natl Acad Sci U S A ; 110(1): 312-7, 2013 Jan 02.

Artigo em Inglês | MEDLINE | ID: mdl-23248303

8.

Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation.

Li, Yanping; Takahashi, Maho; Stork, Philip J S.

J Biol Chem ; 288(38): 27646-27657, 2013 Sep 20.

Artigo em Inglês | MEDLINE | ID: mdl-23893412

9.

Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration.

Takahashi, Maho; Dillon, Tara J; Liu, Chang; Kariya, Yumi; Wang, Zhiping; Stork, Philip J S.

J Biol Chem ; 288(39): 27712-23, 2013 Sep 27.

Artigo em Inglês | MEDLINE | ID: mdl-23946483

10.

B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells.

Dillon, Tara J; Takahashi, Maho; Li, Yanping; Tavisala, Srilatha; Murray, Susan E; Moran, Amy E; Parker, David C; Stork, Philip J S.

Int Immunol ; 25(4): 259-69, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23334952

11.

Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation.

Stork, Philip J S; Schmitt, John M.

Trends Cell Biol ; 12(6): 258-66, 2002 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-12074885

12.

Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation.

Wang, Zhiping; Dillon, Tara J; Pokala, Viji; Mishra, Snigdha; Labudda, Kirstin; Hunter, Brian; Stork, Philip J S.

Mol Cell Biol ; 26(6): 2130-45, 2006 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-16507992

13.

Does Rap1 deserve a bad Rap?

Stork, Philip J S.

Trends Biochem Sci ; 28(5): 267-75, 2003 May.

Artigo em Inglês | MEDLINE | ID: mdl-12765839

14.

Ras-independent activation of ERK signaling via the torso receptor tyrosine kinase is mediated by Rap1.

Mishra, Snigdha; Smolik, Sarah M; Forte, Michael A; Stork, Philip J S.

Curr Biol ; 15(4): 366-70, 2005 Feb 22.

Artigo em Inglês | MEDLINE | ID: mdl-15723799

15.

Regulation of the small GTPase Rap1 and extracellular signal-regulated kinases by the costimulatory molecule CTLA-4.

Dillon, Tara J; Carey, Kendall D; Wetzel, Scott A; Parker, David C; Stork, Philip J S.

Mol Cell Biol ; 25(10): 4117-28, 2005 May.

Artigo em Inglês | MEDLINE | ID: mdl-15870282

16.

Directing NGF's actions: it's a Rap.

Stork, Philip J S.

Nat Cell Biol ; 7(4): 338-9, 2005 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-15803132

17.

Analysis of K-Ras Interactions by Biotin Ligase Tagging.

Ritchie, Christopher; Mack, Andrew; Harper, Logan; Alfadhli, Ayna; Stork, Philip J S; Nan, Xiaolin; Barklis, Eric.

Cancer Genomics Proteomics ; 14(4): 225-239, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28647697

18.

Phosphorylation of the C-Raf N Region Promotes Raf Dimerization.

Takahashi, Maho; Li, Yanping; Dillon, Tara J; Kariya, Yumi; Stork, Philip J S.

Mol Cell Biol ; 37(19)2017 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-28694330

19.

Liberated PKA Catalytic Subunits Associate with the Membrane via Myristoylation to Preferentially Phosphorylate Membrane Substrates.

Tillo, Shane E; Xiong, Wei-Hong; Takahashi, Maho; Miao, Sheng; Andrade, Adriana L; Fortin, Dale A; Yang, Guang; Qin, Maozhen; Smoody, Barbara F; Stork, Philip J S; Zhong, Haining.

Cell Rep ; 19(3): 617-629, 2017 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-28423323

20.

ERK5 induces ankrd1 for catecholamine biosynthesis and homeostasis in adrenal medullary cells.

Obara, Yutaro; Nagasawa, Ryusuke; Nemoto, Wataru; Pellegrino, Michael J; Takahashi, Maho; Habecker, Beth A; Stork, Philip J S; Ichiyanagi, Osamu; Ito, Hiromi; Tomita, Yoshihiko; Ishii, Kuniaki; Nakahata, Norimichi.

Cell Signal ; 28(3): 177-189, 2016 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-26739108

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