Detalhe da pesquisa
1.
The PAX5-JAK2 translocation acts as dual-hit mutation that promotes aggressive B-cell leukemia via nuclear STAT5 activation.
EMBO J
; 41(7): e108397, 2022 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35156727
2.
CD371-positive pediatric B-cell acute lymphoblastic leukemia: propensity to lineage switch and slow early response to treatment.
Blood
; 143(17): 1738-1751, 2024 Apr 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38215390
3.
ETV6-NCOA2 fusion induces T/myeloid mixed-phenotype leukemia through transformation of nonthymic hematopoietic progenitor cells.
Blood
; 139(3): 399-412, 2022 01 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34624096
4.
Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement.
Haematologica
; 108(3): 717-731, 2023 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35484682
5.
Molecular role of the PAX5-ETV6 oncoprotein in promoting B-cell acute lymphoblastic leukemia.
EMBO J
; 36(6): 718-735, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28219927
6.
Expression of RUNX1-JAK2 in Human Induced Pluripotent Stem Cell-Derived Hematopoietic Cells Activates the JAK-STAT and MYC Pathways.
Int J Mol Sci
; 22(14)2021 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34299194
7.
The role of the Janus-faced transcription factor PAX5-JAK2 in acute lymphoblastic leukemia.
Blood
; 125(8): 1282-91, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25515960
8.
CD371 cell surface expression: a unique feature of DUX4-rearranged acute lymphoblastic leukemia.
Haematologica
; 104(8): e352-e355, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705095
9.
ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
Blood
; 117(9): 2658-67, 2011 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-21224468
10.
Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study.
Blood
; 117(26): 7102-11, 2011 Jun 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-21551233
11.
Prospective use of molecular minimal residual disease for risk stratification in children and adolescents with acute lymphoblastic leukemia : Long-term results of the AIEOP-BFM ALL 2000 trial in Austria.
Wien Klin Wochenschr
; 2023 Aug 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-37535134
12.
Treatment outcome of CRLF2-rearranged childhood acute lymphoblastic leukaemia: a comparative analysis of the AIEOP-BFM and UK NCRI-CCLG study groups.
Br J Haematol
; 158(6): 772-7, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22816614
13.
Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group.
Blood
; 115(5): 1006-17, 2010 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-19965641
14.
Novel prognostic subgroups in childhood 11q23/MLL-rearranged acute myeloid leukemia: results of an international retrospective study.
Blood
; 114(12): 2489-96, 2009 Sep 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-19528532
15.
Imatinib-induced long-term remission in a relapsed RCSD1-ABL1-positive acute lymphoblastic leukemia.
Haematologica
; 101(8): e332-5, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27125982
16.
Copy Number Changes and Allele Distribution Patterns of Chromosome 21 in B Cell Precursor Acute Lymphoblastic Leukemia.
Cancers (Basel)
; 13(18)2021 Sep 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-34572826
17.
Prognostic relevance of TLX3 (HOX11L2) expression in childhood T-cell acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing early and late re-intensification elements.
Br J Haematol
; 148(2): 293-300, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-19821827
18.
Prognostic relevance of dic(9;20)(p11;q13) in childhood B-cell precursor acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing an intensive induction and post-induction consolidation therapy.
Br J Haematol
; 149(1): 93-100, 2010 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-20067563
19.
Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome.
Lancet
; 372(9648): 1484-92, 2008 Oct 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18805579
20.
Molecular characterization and clinical impact of t(11;15)(q23;q14-15) MLL-CASC5 rearrangement.
Haematologica
; 99(1): e11-3, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24425691