Detalhe da pesquisa
1.
Detection of circulating tumor DNA with ultradeep sequencing of plasma cell-free DNA for monitoring minimal residual disease and early detection of recurrence in early-stage lung cancer.
Cancer
; 130(10): 1758-1765, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38422026
2.
Circulating tumor DNA-based molecular residual disease detection for treatment monitoring in advanced melanoma patients.
Cancer
; 129(11): 1723-1734, 2023 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36869646
3.
Evidence of mutations in RIC3 acetylcholine receptor chaperone as a novel cause of autosomal-dominant Parkinson's disease with non-motor phenotypes.
J Med Genet
; 53(8): 559-66, 2016 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055476
4.
Discovery of a frameshift mutation in podocalyxin-like (PODXL) gene, coding for a neural adhesion molecule, as causal for autosomal-recessive juvenile Parkinsonism.
J Med Genet
; 53(7): 450-6, 2016 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864383
5.
Early real-world experience monitoring circulating tumor DNA in resected early-stage non-small cell lung cancer.
J Thorac Cardiovasc Surg
; 2024 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-38244856
6.
Personalized, tumor-informed, circulating tumor DNA assay for detecting minimal residual disease in non-small cell lung cancer patients receiving curative treatments.
Thorac Cancer
; 15(13): 1095-1102, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38558374
7.
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Cancer Discov
; 14(2): 258-273, 2024 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37823831
8.
Longitudinal Monitoring of Circulating Tumor DNA to Assess the Efficacy of Immune Checkpoint Inhibitors in Patients With Advanced Genitourinary Malignancies.
JCO Precis Oncol
; 7: e2300131, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37467457
9.
Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours.
Genome Med
; 15(1): 67, 2023 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37679810
10.
Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency.
Clin Cancer Res
; 29(23): 4770-4783, 2023 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37126021
11.
ctDNA-based detection of molecular residual disease in stage I-III non-small cell lung cancer patients treated with definitive radiotherapy.
Front Oncol
; 13: 1253629, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37795442
12.
Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset.
J Clin Oncol
; 41(4): 766-777, 2023 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36240479
13.
Germline Biallelic Mismatch Repair Deficiency in Childhood Glioblastoma and Implications for Clinical Management.
Neurol India
; 70(2): 772-774, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35532657
14.
Feasibility of Longitudinal ctDNA Assessment in Patients with Uterine and Extra-Uterine Leiomyosarcoma.
Cancers (Basel)
; 15(1)2022 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36612153
15.
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency.
Nat Med
; 28(1): 125-135, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34992263
16.
Dual role of allele-specific DNA hypermethylation within the TERT promoter in cancer.
J Clin Invest
; 131(21)2021 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34720085
17.
Mutations in the RAS/MAPK Pathway Drive Replication Repair-Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition.
Cancer Discov
; 11(6): 1454-1467, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33563663
18.
DNA Polymerase and Mismatch Repair Exert Distinct Microsatellite Instability Signatures in Normal and Malignant Human Cells.
Cancer Discov
; 11(5): 1176-1191, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33355208
19.
Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade.
Cancer Res
; 80(24): 5606-5618, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32938641
20.
Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study.
JCO Precis Oncol
; 6: e2100286, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35235414