Detalhe da pesquisa
1.
Inhibition of post-lanosterol biosynthesis by fentanyl: potential implications for Fetal Fentanyl Syndrome (FFS).
Mol Psychiatry
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38844533
2.
Vaping Induced Cannabidiol (CBD) Oxidation Product CBD Quinone Forms Protein Adducts with KEAP1 and Activates KEAP1-Nrf2 Genes.
Chem Res Toxicol
; 36(4): 565-569, 2023 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-36999736
3.
Generation and validation of a conditional knockout mouse model for the study of the Smith-Lemli-Opitz syndrome.
J Lipid Res
; 62: 100002, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33410752
4.
Staphylococcus aureus Peptide Methionine Sulfoxide Reductases Protect from Human Whole-Blood Killing.
Infect Immun
; 89(8): e0014621, 2021 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34001560
5.
Maternal cariprazine exposure inhibits embryonic and postnatal brain cholesterol biosynthesis.
Mol Psychiatry
; 25(11): 2685-2694, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32504050
6.
Modified sites and functional consequences of 4-oxo-2-nonenal adducts in HDL that are elevated in familial hypercholesterolemia.
J Biol Chem
; 294(50): 19022-19033, 2019 12 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31666337
7.
Maternal aripiprazole exposure interacts with 7-dehydrocholesterol reductase mutations and alters embryonic neurodevelopment.
Mol Psychiatry
; 24(4): 491-500, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30742019
8.
Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.
J Lipid Res
; 60(2): 360-374, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30482805
9.
Chemoproteomics Reveals Chemical Diversity and Dynamics of 4-Oxo-2-nonenal Modifications in Cells.
Mol Cell Proteomics
; 16(10): 1789-1800, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28814509
10.
Systematic and Quantitative Assessment of Hydrogen Peroxide Reactivity With Cysteines Across Human Proteomes.
Mol Cell Proteomics
; 16(10): 1815-1828, 2017 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827280
11.
Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis.
Toxicol Appl Pharmacol
; 349: 21-28, 2018 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29698737
12.
Vulnerability of DHCR7+/- mutation carriers to aripiprazole and trazodone exposure.
J Lipid Res
; 58(11): 2139-2146, 2017 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972118
13.
A Chemoproteomic Platform To Assess Bioactivation Potential of Drugs.
Chem Res Toxicol
; 30(10): 1797-1803, 2017 10 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28960974
14.
Inhibitors of 7-Dehydrocholesterol Reductase: Screening of a Collection of Pharmacologically Active Compounds in Neuro2a Cells.
Chem Res Toxicol
; 29(5): 892-900, 2016 05 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27097157
15.
Alkylation damage by lipid electrophiles targets functional protein systems.
Mol Cell Proteomics
; 13(3): 849-59, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24429493
16.
Quantitative chemoproteomics for site-specific analysis of protein alkylation by 4-hydroxy-2-nonenal in cells.
Anal Chem
; 87(5): 2535-41, 2015 Mar 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25654326
17.
Site-specific, intramolecular cross-linking of Pin1 active site residues by the lipid electrophile 4-oxo-2-nonenal.
Chem Res Toxicol
; 28(4): 817-27, 2015 Apr 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-25739016
18.
Erratum: Lysophospholipases cooperate to mediate lipid homeostasis and lysophospholipid signaling.
J Lipid Res
; 60(7): 1345, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31262966
19.
Regulation of phospholipase D activity and phosphatidic acid production after purinergic (P2Y6) receptor stimulation.
J Biol Chem
; 288(28): 20477-87, 2013 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23723068
20.
ω-Alkynyl lipid surrogates for polyunsaturated fatty acids: free radical and enzymatic oxidations.
J Am Chem Soc
; 136(32): 11529-39, 2014 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-25034362