Detalhe da pesquisa
1.
Synthesis and evaluation of novel benzotropolones as Atg4B inhibiting autophagy blockers.
Bioorg Chem
; 87: 163-168, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30884310
2.
Deciphering the Mechanism of Human Carbonic Anhydrases Inhibition with Sulfocoumarins: Computational and Experimental Studies.
Chemistry
; 24(31): 7840-7844, 2018 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29603439
3.
Synthesis of novel 5-amino-1,3,4-thiadiazole-2-sulfonamide containing acridine sulfonamide/carboxamide compounds and investigation of their inhibition effects on human carbonic anhydrase I, II, IV and VII.
Bioorg Chem
; 77: 101-105, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29353727
4.
Effective Access to Multivalent Inhibitors of Carbonic Anhydrases Promoted by Peptide Bioconjugation.
Chemistry
; 23(28): 6788-6794, 2017 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28225196
5.
Microwave assisted synthesis of novel tetrazole/sulfonamide derivatives based on octahydroacridine, xanthene and chromene skeletons as inhibitors of the carbonic anhydrases isoforms I, II, IV and VII.
Bioorg Med Chem Lett
; 27(1): 86-89, 2017 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27876475
6.
Human carbonic anhydrase inhibitory profile of mono- and bis-sulfonamides synthesized via a direct sulfochlorination of 3- and 4-(hetero)arylisoxazol-5-amine scaffolds.
Bioorg Med Chem
; 25(6): 1914-1925, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28237553
7.
A class of carbonic anhydrase I - selective activators.
J Enzyme Inhib Med Chem
; 32(1): 37-46, 2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-27798977
8.
Microwave assisted synthesis of novel acridine-acetazolamide conjugates and investigation of their inhibition effects on human carbonic anhydrase isoforms hCA I, II, IV and VII.
Bioorg Med Chem
; 24(16): 3548-55, 2016 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27298005
9.
Synthesis and carbonic anhydrase I, II, IV and XII inhibitory properties of N-protected amino acid - sulfonamide conjugates.
J Enzyme Inhib Med Chem
; 31(6): 1476-83, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26899532
10.
Synthesis and carbonic anhydrase inhibitory properties of amino acid - coumarin/quinolinone conjugates incorporating glycine, alanine and phenylalanine moieties.
J Enzyme Inhib Med Chem
; 31(6): 1198-202, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26586254
11.
Inhibitory effects of benzimidazole containing new phenolic Mannich bases on human carbonic anhydrase isoforms hCA I and II.
J Enzyme Inhib Med Chem
; 31(6): 1540-4, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26985571
12.
The inhibitory effects of phenolic Mannich bases on carbonic anhydrase I and II isoenzymes.
J Enzyme Inhib Med Chem
; 31(6): 1678-81, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26808123
13.
Synthesis, characterization and carbonic anhydrase inhibitory activity of novel benzothiazole derivatives.
J Enzyme Inhib Med Chem
; 31(6): 1221-5, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26598927
14.
Multimeric xanthates as carbonic anhydrase inhibitors.
J Enzyme Inhib Med Chem
; 31(6): 946-52, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26235915
15.
Carbonic anhydrase inhibition and cytotoxicity studies of Mannich base derivatives of thymol.
J Enzyme Inhib Med Chem
; 31(6): 1375-80, 2016 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26850788
16.
Synthesis and bioactivity studies of 1-aryl-3-(2-hydroxyethylthio)-1-propanones.
J Enzyme Inhib Med Chem
; 31(sup3): 105-109, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27435293
17.
Isoform-selective inhibitory profile of 2-imidazoline-substituted benzene sulfonamides against a panel of human carbonic anhydrases.
J Enzyme Inhib Med Chem
; 31(sup1): 197-202, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27160030
18.
9,10-Dibromo-N-aryl-9,10-dihydro-9,10-[3,4]epipyrroloanthracene-12,14-diones: Synthesis and Investigation of Their Effects on Carbonic Anhydrase Isozymes I, II, IX, and XII.
Arch Pharm (Weinheim)
; 349(6): 466-74, 2016 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-27174792
19.
6-Substituted 1,2-benzoxathiine-2,2-dioxides are isoform-selective inhibitors of human carbonic anhydrases IX, XII and VA.
Org Biomol Chem
; 13(1): 77-80, 2015 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-25373598
20.
Exploring carbonic anhydrase inhibition with multimeric coumarins displayed on a fullerene scaffold.
Org Biomol Chem
; 13(27): 7445-51, 2015 Jul 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-26058669