Detalhe da pesquisa
1.
Investigation of Multi-Subunit Mycobacterium tuberculosis DNA-Directed RNA Polymerase and Its Rifampicin Resistant Mutants.
Int J Mol Sci
; 24(4)2023 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834726
2.
Human Cytochrome P450 1, 2, 3 Families as Pharmacogenes with Emphases on Their Antimalarial and Antituberculosis Drugs and Prevalent African Alleles.
Int J Mol Sci
; 24(4)2023 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834793
3.
Structural and Functional Annotation of Hypothetical Proteins from the Microsporidia Species Vittaforma corneae ATCC 50505 Using in silico Approaches.
Int J Mol Sci
; 24(4)2023 Feb 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36834914
4.
Slipknot or Crystallographic Error: A Computational Analysis of the Plasmodium falciparum DHFR Structural Folds.
Int J Mol Sci
; 23(3)2022 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35163439
5.
The Structural Basis of Mycobacterium tuberculosis RpoB Drug-Resistant Clinical Mutations on Rifampicin Drug Binding.
Molecules
; 27(3)2022 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164151
6.
GTP Cyclohydrolase I as a Potential Drug Target: New Insights into Its Allosteric Modulation via Normal Mode Analysis.
J Chem Inf Model
; 61(9): 4701-4719, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34450011
7.
Differences in Gluco and Galacto Substrate-Binding Interactions in a Dual 6Pß-Glucosidase/6Pß-Galactosidase Glycoside Hydrolase 1 Enzyme from Bacillus licheniformis.
J Chem Inf Model
; 61(9): 4554-4570, 2021 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34423980
8.
Decoding the Molecular Effects of Atovaquone Linked Resistant Mutations on Plasmodium falciparum Cytb-ISP Complex in the Phospholipid Bilayer Membrane.
Int J Mol Sci
; 22(4)2021 Feb 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33670016
9.
Force Field Parameters for Fe2+4S2-4 Clusters of Dihydropyrimidine Dehydrogenase, the 5-Fluorouracil Cancer Drug Deactivation Protein: A Step towards In Silico Pharmacogenomics Studies.
Molecules
; 26(10)2021 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34069161
10.
Characterisation of plasmodial transketolases and identification of potential inhibitors: an in silico study.
Malar J
; 19(1): 442, 2020 Nov 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256744
11.
Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 Mpro.
J Chem Inf Model
; 60(10): 5080-5102, 2020 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-32853525
12.
X-ray Structure, Bioinformatics Analysis, and Substrate Specificity of a 6-Phospho-ß-glucosidase Glycoside Hydrolase 1 Enzyme from Bacillus licheniformis.
J Chem Inf Model
; 60(12): 6392-6407, 2020 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-33166469
13.
Structural Characterization of Carbonic Anhydrase VIII and Effects of Missense Single Nucleotide Variations to Protein Structure and Function.
Int J Mol Sci
; 21(8)2020 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32316137
14.
Identification of Selective Novel Hits against Plasmodium falciparum Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using in silico Approaches.
Int J Mol Sci
; 21(11)2020 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32471245
15.
Alpha-Carbonic Anhydrases from Hydrothermal Vent Sources as Potential Carbon Dioxide Sequestration Agents: In Silico Sequence, Structure and Dynamics Analyses.
Int J Mol Sci
; 21(21)2020 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-33138066
16.
Integrated Computational Approaches and Tools forAllosteric Drug Discovery.
Int J Mol Sci
; 21(3)2020 Jan 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32013012
17.
Understanding the Pyrimethamine Drug Resistance Mechanism via Combined Molecular Dynamics and Dynamic Residue Network Analysis.
Molecules
; 25(4)2020 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32085470
18.
H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa.
Genome Res
; 26(2): 271-7, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26627985
19.
MODE-TASK: large-scale protein motion tools.
Bioinformatics
; 34(21): 3759-3763, 2018 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29850770
20.
Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study.
Malar J
; 18(1): 34, 2019 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30728021