Detalhe da pesquisa
1.
Structural evolution of fibril polymorphs during amyloid assembly.
Cell
; 186(26): 5798-5811.e26, 2023 12 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134875
2.
Structural insights into BCDX2 complex function in homologous recombination.
Nature
; 619(7970): 640-649, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344589
3.
Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2.
Proc Natl Acad Sci U S A
; 121(6): e2317756121, 2024 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38300868
4.
Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly.
Am J Hum Genet
; 110(3): 499-515, 2023 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724785
5.
Oxamniquine derivatives overcome Praziquantel treatment limitations for Schistosomiasis.
PLoS Pathog
; 19(7): e1011018, 2023 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37428793
6.
Characterization of an HNA aptamer suggests a non-canonical G-quadruplex motif.
Nucleic Acids Res
; 51(15): 7736-7748, 2023 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37439359
7.
Cucurbit[8]uril Binds Nonterminal Dipeptide Sites with High Affinity and Induces a Type II ß-Turn.
J Am Chem Soc
; 146(11): 7649-7657, 2024 Mar 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38348472
8.
Genome-scale clustered regularly interspaced short palindromic repeats screen identifies nucleotide metabolism as an actionable therapeutic vulnerability in diffuse large B-cell lymphoma.
Haematologica
; 2024 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38841800
9.
Crystal Structure of the RNA Lariat Debranching Enzyme Dbr1 with Hydrolyzed Phosphorothioate RNA Product.
Biochemistry
; 61(24): 2933-2939, 2022 12 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-36484984
10.
A pH Switch Controls Zinc Binding in Tomato Copper-Zinc Superoxide Dismutase.
Biochemistry
; 60(20): 1597-1608, 2021 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-33961402
11.
Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment.
PLoS Pathog
; 15(10): e1007881, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31652296
12.
Catalysts from synthetic genetic polymers.
Nature
; 518(7539): 427-30, 2015 Feb 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-25470036
13.
Retrospective Diagnosis of Ataxia-Telangiectasia in an Adolescent Patient With a Remote History of T-Cell Leukemia.
J Pediatr Hematol Oncol
; 43(1): e138-e140, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31743320
14.
Structure of a Zinc Porphyrin-Substituted Bacterioferritin and Photophysical Properties of Iron Reduction.
Biochemistry
; 59(16): 1618-1629, 2020 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32283930
15.
A mutually induced conformational fit underlies Ca2+-directed interactions between calmodulin and the proximal C terminus of KCNQ4 K+ channels.
J Biol Chem
; 294(15): 6094-6112, 2019 04 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30808708
16.
Correlation between cribriform/intraductal prostatic adenocarcinoma and percent Gleason pattern 4 to a 22-gene genomic classifier.
Prostate
; 80(2): 146-152, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31737920
17.
PAX8 expression and TERT promoter mutations in the nested variant of urothelial carcinoma: a clinicopathologic study with immunohistochemical and molecular correlates.
Mod Pathol
; 33(6): 1165-1171, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31932679
18.
Disulfide bond of Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin is essential to maintain the ADP-ribosylating and vacuolating activities.
Cell Microbiol
; 21(8): e13032, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30977272
19.
A two-step biopolymer nucleation model shows a nonequilibrium critical point.
J Chem Phys
; 153(2): 025102, 2020 Jul 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32668930
20.
Genotype-phenotype correlations in ataxia telangiectasia patients with ATM c.3576G>A and c.8147T>C mutations.
J Med Genet
; 56(5): 308-316, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30819809