Detalhe da pesquisa
1.
Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol
; 141(5): 697-708, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33723967
2.
Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607.
Acta Neuropathol
; 141(6): 983, 2021 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-33830331
3.
Use of molecular modeling aided design to dial out hERG liability in adenosine A(2A) receptor antagonists.
Bioorg Med Chem Lett
; 25(15): 2958-62, 2015 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26048804
4.
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms.
Bioorg Med Chem Lett
; 24(8): 1968-73, 2014 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24666646
5.
Lead optimization of 4,4-biaryl piperidine amides as γ-secretase inhibitors.
Bioorg Med Chem Lett
; 22(9): 3203-7, 2012 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22483609
6.
Parallel medicinal chemistry approaches to selective HDAC1/HDAC2 inhibitor (SHI-1:2) optimization.
Bioorg Med Chem Lett
; 19(4): 1168-72, 2009 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19138845
7.
Evolution of a highly selective and potent 2-(pyridin-2-yl)-1,3,5-triazine Tie-2 kinase inhibitor.
J Med Chem
; 50(4): 611-26, 2007 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-17253678
8.
Recent advances in heterocycle generation using the efficient Ugi multiple-component condensation reaction.
Curr Opin Drug Discov Devel
; 8(6): 776-88, 2005 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-16312152
9.
Library generation via postcondensation modifications of isocyanide-based multicomponent reactions.
Methods Enzymol
; 369: 469-96, 2003.
Artigo
em Inglês
| MEDLINE | ID: mdl-14722968
10.
Design of novel histone deacetylase inhibitors.
Bioorg Med Chem Lett
; 17(16): 4619-24, 2007 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17555962
11.
Solid-phase synthesis and structure-activity relationships of novel biarylethers as melanin-concentrating hormone receptor-1 antagonists.
Bioorg Med Chem Lett
; 16(19): 5066-72, 2006 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-16887348