Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

A forward genetic screen reveals a primary role for Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a and 2b in determining alternative erythrocyte invasion pathways.

Campino, Susana; Marin-Menendez, Alejandro; Kemp, Alison; Cross, Nadia; Drought, Laura; Otto, Thomas D; Benavente, Ernest Diez; Ravenhall, Matt; Schwach, Frank; Girling, Gareth; Manske, Magnus; Theron, Michel; Gould, Kelda; Drury, Eleanor; Clark, Taane G; Kwiatkowski, Dominic P; Pance, Alena; Rayner, Julian C.

PLoS Pathog ; 14(11): e1007436, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30496294

2.

Indels, structural variation, and recombination drive genomic diversity in Plasmodium falciparum.

Miles, Alistair; Iqbal, Zamin; Vauterin, Paul; Pearson, Richard; Campino, Susana; Theron, Michel; Gould, Kelda; Mead, Daniel; Drury, Eleanor; O'Brien, John; Ruano Rubio, Valentin; MacInnis, Bronwyn; Mwangi, Jonathan; Samarakoon, Upeka; Ranford-Cartwright, Lisa; Ferdig, Michael; Hayton, Karen; Su, Xin-Zhuan; Wellems, Thomas; Rayner, Julian; McVean, Gil; Kwiatkowski, Dominic.

Genome Res ; 26(9): 1288-99, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27531718

3.

Study of Plasmodium falciparum DHHC palmitoyl transferases identifies a role for PfDHHC9 in gametocytogenesis.

Tay, Chwen L; Jones, Matthew L; Hodson, Nicola; Theron, Michel; Choudhary, Jyoti S; Rayner, Julian C.

Cell Microbiol ; 18(11): 1596-1610, 2016 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-27060339

4.

Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.

Crosnier, Cécile; Bustamante, Leyla Y; Bartholdson, S Josefin; Bei, Amy K; Theron, Michel; Uchikawa, Makoto; Mboup, Souleymane; Ndir, Omar; Kwiatkowski, Dominic P; Duraisingh, Manoj T; Rayner, Julian C; Wright, Gavin J.

Nature ; 480(7378): 534-7, 2011 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-22080952

5.

Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.

Douglas, Alexander D; Williams, Andrew R; Knuepfer, Ellen; Illingworth, Joseph J; Furze, Julie M; Crosnier, Cécile; Choudhary, Prateek; Bustamante, Leyla Y; Zakutansky, Sara E; Awuah, Dennis K; Alanine, Daniel G W; Theron, Michel; Worth, Andrew; Shimkets, Richard; Rayner, Julian C; Holder, Anthony A; Wright, Gavin J; Draper, Simon J.

J Immunol ; 192(1): 245-58, 2014 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-24293631

6.

Quantitation of malaria parasite-erythrocyte cell-cell interactions using optical tweezers.

Crick, Alex J; Theron, Michel; Tiffert, Teresa; Lew, Virgilio L; Cicuta, Pietro; Rayner, Julian C.

Biophys J ; 107(4): 846-53, 2014 Aug 19.

Artigo em Inglês | MEDLINE | ID: mdl-25140419

7.

Acute myeloid leukemia patients' clinical response to idasanutlin (RG7388) is associated with pre-treatment MDM2 protein expression in leukemic blasts.

Reis, Bernhard; Jukofsky, Lori; Chen, Gong; Martinelli, Giovanni; Zhong, Hua; So, W Venus; Dickinson, Michael J; Drummond, Mark; Assouline, Sarit; Hashemyan, Maneja; Theron, Michel; Blotner, Steven; Lee, Je-Hwan; Kasner, Margaret; Yoon, Sung-Soo; Rueger, Ruediger; Seiter, Karen; Middleton, Steven A; Kelly, Kevin R; Vey, Norbert; Yee, Karen; Nichols, Gwen; Chen, Lin-Chi; Pierceall, William E.

Haematologica ; 101(5): e185-8, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-26869629

8.

An adaptable two-color flow cytometric assay to quantitate the invasion of erythrocytes by Plasmodium falciparum parasites.

Theron, Michel; Hesketh, Richard L; Subramanian, Sathish; Rayner, Julian C.

Cytometry A ; 77(11): 1067-74, 2010 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-20872885

9.

Differential effects of specific cathepsin S inhibition in biocompartments from patients with primary Sjögren syndrome.

Hargreaves, Patrick; Daoudlarian, Douglas; Theron, Michel; Kolb, Fabrice A; Manchester Young, Marianne; Reis, Bernhard; Tiaden, Andre; Bannert, Bettina; Kyburz, Diego; Manigold, Tobias.

Arthritis Res Ther ; 21(1): 175, 2019 07 18.

Artigo em Inglês | MEDLINE | ID: mdl-31319889

10.

An in vitro erythrocyte preference assay reveals that Plasmodium falciparum parasites prefer Type O over Type A erythrocytes.

Theron, Michel; Cross, Nadia; Cawkill, Paula; Bustamante, Leyla Y; Rayner, Julian C.

Sci Rep ; 8(1): 8133, 2018 05 25.

Artigo em Inglês | MEDLINE | ID: mdl-29802282

11.

Cathepsin S inhibition suppresses autoimmune-triggered inflammatory responses in macrophages.

Thanei, Sophia; Theron, Michel; Silva, Ana Patricia; Reis, Bernhard; Branco, Leonore; Schirmbeck, Lucia; Kolb, Fabrice A; Haap, Wolfgang; Schindler, Thomas; Trendelenburg, Marten.

Biochem Pharmacol ; 146: 151-164, 2017 12 15.

Artigo em Inglês | MEDLINE | ID: mdl-28987592

12.

Pharmacodynamic Monitoring of RO5459072, a Small Molecule Inhibitor of Cathepsin S.

Theron, Michel; Bentley, Darren; Nagel, Sandra; Manchester, Marianne; Gerg, Michael; Schindler, Thomas; Silva, Ana; Ecabert, Barbara; Teixeira, Priscila; Perret, Camille; Reis, Bernhard.

Front Immunol ; 8: 806, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-28769925

13.

Genomic analysis of the molecular neuropathology of tuberous sclerosis using a human stem cell model.

Grabole, Nils; Zhang, Jitao David; Aigner, Stefan; Ruderisch, Nadine; Costa, Veronica; Weber, Felix C; Theron, Michel; Berntenis, Nikolaos; Spleiss, Olivia; Ebeling, Martin; Yeo, Gene W; Jagasia, Ravi; Kiialainen, Anna.

Genome Med ; 8(1): 94, 2016 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-27655340

14.

Prevalence of non-pneumonic infections with SARS-correlated virus.

Theron, Michel.

Lancet ; 363(9423): 1825; author reply 1826-7, 2004 May 29.

Artigo em Inglês | MEDLINE | ID: mdl-15172785

15.

SARS viral RNA.

Theron, Michel.

Am J Clin Pathol ; 122(3): 474; author reply 474-5, 2004 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-15362378

16.

Hemozoin (malarial pigment) directly promotes apoptosis of erythroid precursors.

Lamikanra, Abigail A; Theron, Michel; Kooij, Taco W A; Roberts, David J.

PLoS One ; 4(12): e8446, 2009 Dec 24.

Artigo em Inglês | MEDLINE | ID: mdl-20041181

17.

A probable role for IFN-gamma in the development of a lung immunopathology in SARS.

Theron, Michel; Huang, Kao-Jean; Chen, Yu-Wen; Liu, Ching-Chuan; Lei, Huan-Yao.

Cytokine ; 32(1): 30-8, 2005 Oct 07.

Artigo em Inglês | MEDLINE | ID: mdl-16129616

18.

An interferon-gamma-related cytokine storm in SARS patients.

Huang, Kao-Jean; Su, Ih-Jen; Theron, Michel; Wu, Yi-Chun; Lai, Shu-Kuan; Liu, Ching-Chuan; Lei, Huan-Yao.

J Med Virol ; 75(2): 185-94, 2005 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-15602737

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