Detalhe da pesquisa
1.
Comb-structured mRNA vaccine tethered with short double-stranded RNA adjuvants maximizes cellular immunity for cancer treatment.
Proc Natl Acad Sci U S A
; 120(29): e2214320120, 2023 07 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37428918
2.
Carrier-free mRNA vaccine induces robust immunity against SARS-CoV-2 in mice and non-human primates without systemic reactogenicity.
Mol Ther
; 32(5): 1266-1283, 2024 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38569556
3.
Targeting nanoparticles to the brain by exploiting the blood-brain barrier impermeability to selectively label the brain endothelium.
Proc Natl Acad Sci U S A
; 117(32): 19141-19150, 2020 08 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32703811
4.
Poly(ethylene glycol) Crowding as Critical Factor To Determine pDNA Packaging Scheme into Polyplex Micelles for Enhanced Gene Expression.
Biomacromolecules
; 18(1): 36-43, 2017 01 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27990798
5.
Rod-to-Globule Transition of pDNA/PEG-Poly(l-Lysine) Polyplex Micelles Induced by a Collapsed Balance Between DNA Rigidity and PEG Crowdedness.
Small
; 12(9): 1193-200, 2016 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26426541
6.
Toroidal Packaging of pDNA into Block Ionomer Micelles Exerting Promoted in Vivo Gene Expression.
Biomacromolecules
; 16(9): 2664-71, 2015 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26226080
7.
A tadpole-shaped gene carrier with distinct phase segregation in a ternary polymeric micelle.
Soft Matter
; 11(14): 2718-22, 2015 Apr 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-25711768
8.
Co-encapsulation of Cas9 mRNA and guide RNA in polyplex micelles enables genome editing in mouse brain.
J Control Release
; 332: 260-268, 2021 04 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33647431
9.
Enzymatically Transformable Polymersome-Based Nanotherapeutics to Eliminate Minimal Relapsable Cancer.
Adv Mater
; 33(49): e2105254, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34622509
10.
Transient stealth coating of liver sinusoidal wall by anchoring two-armed PEG for retargeting nanomedicines.
Sci Adv
; 6(26): eabb8133, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32637625
11.
Dual-Sensitive Nanomicelles Enhancing Systemic Delivery of Therapeutically Active Antibodies Specifically into the Brain.
ACS Nano
; 14(6): 6729-6742, 2020 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32431145
12.
Single-Stranded DNA-Packaged Polyplex Micelle as Adeno-Associated-Virus-Inspired Compact Vector to Systemically Target Stroma-Rich Pancreatic Cancer.
ACS Nano
; 13(11): 12732-12742, 2019 11 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31647640
13.
Precise tuning of disulphide crosslinking in mRNA polyplex micelles for optimising extracellular and intracellular nuclease tolerability.
J Drug Target
; 27(5-6): 670-680, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-30499743
14.
Effect of shear stress on structure and function of polyplex micelles from poly(ethylene glycol)-poly(l-lysine) block copolymers as systemic gene delivery carrier.
Biomaterials
; 126: 31-38, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28254691
15.
Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting.
Biomaterials
; 113: 253-265, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27835820
16.
Optimized rod length of polyplex micelles for maximizing transfection efficiency and their performance in systemic gene therapy against stroma-rich pancreatic tumors.
Biomaterials
; 35(20): 5359-5368, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24720877
17.
Targeted gene delivery by polyplex micelles with crowded PEG palisade and cRGD moiety for systemic treatment of pancreatic tumors.
Biomaterials
; 35(10): 3416-26, 2014 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-24439417
18.
Enhanced gene expression promoted by the quantized folding of pDNA within polyplex micelles.
Biomaterials
; 33(1): 325-32, 2012 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21993237
19.
Homo-catiomer integration into PEGylated polyplex micelle from block-catiomer for systemic anti-angiogenic gene therapy for fibrotic pancreatic tumors.
Biomaterials
; 33(18): 4722-30, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22444644