Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Frame-shifted APOBEC3A encodes two alternative proapoptotic proteins that target the mitochondrial network.

Caval, Vincent; Suspène, Rodolphe; Khalfi, Pierre; Gaillard, Julien; Caignard, Grégory; Vitour, Damien; Roingeard, Philippe; Vartanian, Jean-Pierre; Wain-Hobson, Simon.

J Biol Chem ; 297(3): 101081, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-34403699

2.

Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA.

Caval, Vincent; Jiao, Wenjuan; Berry, Noémie; Khalfi, Pierre; Pitré, Emmanuelle; Thiers, Valérie; Vartanian, Jean-Pierre; Wain-Hobson, Simon; Suspène, Rodolphe.

BMC Genomics ; 20(1): 858, 2019 Nov 14.

Artigo em Inglês | MEDLINE | ID: mdl-31726973

3.

Strong antigen-specific T-cell immunity induced by a recombinant human TERT measles virus vaccine and amplified by a DNA/viral vector prime boost in IFNAR/CD46 mice.

Pliquet, Elodie; Ruffie, Claude; Escande, Marie; Thalmensi, Jessie; Najburg, Valérie; Combredet, Chantal; Bestetti, Thomas; Julithe, Marion; Liard, Christelle; Huet, Thierry; Wain-Hobson, Simon; Tangy, Frédéric; Langlade-Demoyen, Pierre.

Cancer Immunol Immunother ; 68(4): 533-544, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30656384

4.

Self-cytoplasmic DNA upregulates the mutator enzyme APOBEC3A leading to chromosomal DNA damage.

Suspène, Rodolphe; Mussil, Bianka; Laude, Hélène; Caval, Vincent; Berry, Noémie; Bouzidi, Mohamed S; Thiers, Valérie; Wain-Hobson, Simon; Vartanian, Jean-Pierre.

Nucleic Acids Res ; 45(6): 3231-3241, 2017 04 07.

Artigo em Inglês | MEDLINE | ID: mdl-28100701

5.

Molecular basis of the attenuated phenotype of human APOBEC3B DNA mutator enzyme.

Caval, Vincent; Bouzidi, Mohamed S; Suspène, Rodolphe; Laude, Hélène; Dumargne, Marie-Charlotte; Bashamboo, Anu; Krey, Thomas; Vartanian, Jean-Pierre; Wain-Hobson, Simon.

Nucleic Acids Res ; 43(19): 9340-9, 2015 Oct 30.

Artigo em Inglês | MEDLINE | ID: mdl-26384561

6.

PCR mediated recombination impacts the analysis of hepatitis B Virus covalently closed circular DNA.

Suspène, Rodolphe; Thiers, Valérie; Vartanian, Jean-Pierre; Wain-Hobson, Simon.

Retrovirology ; 13(1): 84, 2016 Dec 20.

Artigo em Inglês | MEDLINE | ID: mdl-27998270

7.

Orthologous mammalian APOBEC3A cytidine deaminases hypermutate nuclear DNA.

Caval, Vincent; Suspène, Rodolphe; Vartanian, Jean-Pierre; Wain-Hobson, Simon.

Mol Biol Evol ; 31(2): 330-40, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24162735

8.

H5N1 viral-engineering dangers will not go away.

Wain-Hobson, Simon.

Nature ; 495(7442): 411, 2013 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-23538789

9.

Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism.

Suspène, Rodolphe; Aynaud, Marie-Ming; Guétard, Denise; Henry, Michel; Eckhoff, Grace; Marchio, Agnès; Pineau, Pascal; Dejean, Anne; Vartanian, Jean-Pierre; Wain-Hobson, Simon.

Proc Natl Acad Sci U S A ; 108(12): 4858-63, 2011 Mar 22.

Artigo em Inglês | MEDLINE | ID: mdl-21368204

10.

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A.

Aynaud, Marie-Ming; Suspène, Rodolphe; Vidalain, Pierre-Olivier; Mussil, Bianka; Guétard, Denise; Tangy, Frédéric; Wain-Hobson, Simon; Vartanian, Jean-Pierre.

J Biol Chem ; 287(46): 39182-92, 2012 Nov 09.

Artigo em Inglês | MEDLINE | ID: mdl-22977230

11.

Structural variability of the herpes simplex virus 1 genome in vitro and in vivo.

Mahiet, Charlotte; Ergani, Ayla; Huot, Nicolas; Alende, Nicolas; Azough, Ahmed; Salvaire, Fabrice; Bensimon, Aaron; Conseiller, Emmanuel; Wain-Hobson, Simon; Labetoulle, Marc; Barradeau, Sébastien.

J Virol ; 86(16): 8592-601, 2012 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-22674981

12.

Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1.

Ko, Nga Ling; Birlouez, Emmanuel; Wain-Hobson, Simon; Mahieux, Renaud; Vartanian, Jean-Pierre.

J Gen Virol ; 93(Pt 12): 2646-2651, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22993189

13.

Lethal mutagenesis of foot-and-mouth disease virus involves shifts in sequence space.

Perales, Celia; Henry, Michel; Domingo, Esteban; Wain-Hobson, Simon; Vartanian, Jean-Pierre.

J Virol ; 85(23): 12227-40, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-21917974

14.

Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo.

Suspène, Rodolphe; Aynaud, Marie-Ming; Koch, Stefanie; Pasdeloup, David; Labetoulle, Marc; Gaertner, Barbara; Vartanian, Jean-Pierre; Meyerhans, Andreas; Wain-Hobson, Simon.

J Virol ; 85(15): 7594-602, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21632763

15.

Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines.

Suspène, Rodolphe; Petit, Vincent; Puyraimond-Zemmour, David; Aynaud, Marie-Ming; Henry, Michel; Guétard, Denise; Rusniok, Christophe; Wain-Hobson, Simon; Vartanian, Jean-Pierre.

J Virol ; 85(5): 2458-62, 2011 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-21159878

16.

Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis.

Vartanian, Jean-Pierre; Henry, Michel; Marchio, Agnès; Suspène, Rodolphe; Aynaud, Marie-Ming; Guétard, Denise; Cervantes-Gonzalez, Minerva; Battiston, Carlo; Mazzaferro, Vincenzo; Pineau, Pascal; Dejean, Anne; Wain-Hobson, Simon.

PLoS Pathog ; 6(5): e1000928, 2010 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-20523896

17.

Targeting human telomerase reverse transcriptase with recombinant lentivector is highly effective to stimulate antitumor CD8 T-cell immunity in vivo.

Adotévi, Olivier; Mollier, Karine; Neuveut, Christine; Dosset, Magalie; Ravel, Patrice; Fridman, Wolf-Hervé; Tartour, Eric; Charneau, Pierre; Wain-Hobson, Simon; Langlade-Demoyen, Pierre.

Blood ; 115(15): 3025-32, 2010 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-20130242

18.

Research investment: Vaccine research loses out.

Hale, Peter; Wain-Hobson, Simon; Weiss, Robin A.

Nature ; 478(7368): 188, 2011 Oct 12.

Artigo em Inglês | MEDLINE | ID: mdl-21993749

19.

Luc Montagnier (1932-2022).

Weiss, Robin A; Wain-Hobson, Simon.

Science ; 375(6586): 1235, 2022 Mar 18.

Artigo em Inglês | MEDLINE | ID: mdl-35298253

20.

APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo.

Fan, Jun; Ma, Guangyong; Nosaka, Kisato; Tanabe, Junko; Satou, Yorifumi; Koito, Atsushi; Wain-Hobson, Simon; Vartanian, Jean-Pierre; Matsuoka, Masao.

J Virol ; 84(14): 7278-87, 2010 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-20463074

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