Detalhe da pesquisa
1.
A prolyl-isomerase mediates dopamine-dependent plasticity and cocaine motor sensitization.
Cell
; 154(3): 637-50, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23911326
2.
Stereospecific gating of functional motions in Pin1.
Proc Natl Acad Sci U S A
; 108(30): 12289-94, 2011 Jul 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21746900
3.
Toward flexibility-activity relationships by NMR spectroscopy: dynamics of Pin1 ligands.
J Am Chem Soc
; 132(16): 5607-9, 2010 Apr 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-20356313
4.
Potent activity of a PK/PBAN analog with an (E)-alkene, trans-Pro mimic identifies the Pro orientation and core conformation during interaction with HevPBANR-C receptor.
Bioorg Med Chem
; 17(12): 4216-20, 2009 Jun 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19356938
5.
The effect of a trans-locked Gly-Pro alkene isostere on collagen triple helix stability.
J Am Chem Soc
; 130(16): 5396-7, 2008 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-18366169
6.
Evaluation of insect CAP2b analogs with either an (E)-alkene, trans- or a (Z)-alkene, cis-Pro isostere identifies the Pro orientation for antidiuretic activity in the stink bug.
Peptides
; 41: 101-6, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23036324
7.
Structural and kinetic analysis of prolyl-isomerization/phosphorylation cross-talk in the CTD code.
ACS Chem Biol
; 7(8): 1462-70, 2012 Aug 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-22670809
8.
Evaluation of a PK/PBAN analog with an (E)-alkene, trans-Pro isostere identifies the Pro orientation for activity in four diverse PK/PBAN bioassays.
Peptides
; 30(7): 1254-9, 2009 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-19416747
9.
Peptidyl-prolyl isomerase inhibitors.
Biopolymers
; 84(2): 125-46, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16302169
10.
Conformationally locked isostere of phosphoSer-cis-Pro inhibits Pin1 23-fold better than phosphoSer-trans-Pro isostere.
J Am Chem Soc
; 126(47): 15533-42, 2004 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15563182
11.
Serine-cis-proline and serine-trans-proline isosteres: stereoselective synthesis of (Z)- and (E)-alkene mimics by Still-Wittig and Ireland-Claisen rearrangements.
J Org Chem
; 68(6): 2343-9, 2003 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-12636401