Detalhe da pesquisa
1.
Anti-prion drugs do not improve survival in novel knock-in models of inherited prion disease.
PLoS Pathog
; 20(4): e1012087, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38557815
2.
A single protective polymorphism in the prion protein blocks cross-species prion replication in cultured cells.
J Neurochem
; 165(2): 230-245, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36511154
3.
Genetically engineered cellular models of prion propagation.
Cell Tissue Res
; 392(1): 63-80, 2023 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35581386
4.
The aminoglycoside G418 hinders de novo prion infection in cultured cells.
J Biol Chem
; 297(3): 101073, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34390689
5.
Identification of a homology-independent linchpin domain controlling mouse and bank vole prion protein conversion.
PLoS Pathog
; 16(9): e1008875, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32898162
6.
Full restoration of specific infectivity and strain properties from pure mammalian prion protein.
PLoS Pathog
; 15(3): e1007662, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30908557
7.
The existence of Aß strains and their potential for driving phenotypic heterogeneity in Alzheimer's disease.
Acta Neuropathol
; 142(1): 17-39, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32743745
8.
Structural heterogeneity and intersubject variability of Aß in familial and sporadic Alzheimer's disease.
Proc Natl Acad Sci U S A
; 115(4): E782-E791, 2018 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-29311311
9.
Engineering a murine cell line for the stable propagation of hamster prions.
J Biol Chem
; 294(13): 4911-4923, 2019 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-30705093
10.
Cellular models for discovering prion disease therapeutics: Progress and challenges.
J Neurochem
; 153(2): 150-172, 2020 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31943194
11.
The function of the cellular prion protein in health and disease.
Acta Neuropathol
; 135(2): 159-178, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29151170
12.
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.
Proc Natl Acad Sci U S A
; 112(38): E5308-17, 2015 Sep 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-26324905
13.
Propagation of prions causing synucleinopathies in cultured cells.
Proc Natl Acad Sci U S A
; 112(35): E4949-58, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26286986
14.
Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
J Virol
; 90(21): 9558-9569, 2016 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27440899
15.
Distinct synthetic Aß prion strains producing different amyloid deposits in bigenic mice.
Proc Natl Acad Sci U S A
; 111(28): 10329-34, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982137
16.
Serial propagation of distinct strains of Aß prions from Alzheimer's disease patients.
Proc Natl Acad Sci U S A
; 111(28): 10323-8, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24982139
17.
Evidence that bank vole PrP is a universal acceptor for prions.
PLoS Pathog
; 10(4): e1003990, 2014 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-24699458
18.
Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.
Ann Neurol
; 78(4): 540-53, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26094969
19.
Towards authentic transgenic mouse models of heritable PrP prion diseases.
Acta Neuropathol
; 132(4): 593-610, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27350609
20.
Drug resistance confounding prion therapeutics.
Proc Natl Acad Sci U S A
; 110(44): E4160-9, 2013 Oct 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-24128760