Detalhe da pesquisa
1.
Pharmacological inhibition of polo like kinase 2 (PLK2) does not cause chromosomal damage or result in the formation of micronuclei.
Toxicol Appl Pharmacol
; 269(1): 1-7, 2013 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23466428
2.
Discovery of (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline (ELND006) and (R)-4-cyclopropyl-8-fluoro-5-(6-(trifluoromethyl)pyridin-3-ylsulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline (ELND007): metabolically stable γ-secretase Inhibitors that selectively inhibit the production of amyloid-ß over Notch.
J Med Chem
; 56(13): 5261-74, 2013 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23713656
3.
Development of ALZET® osmotic pump compatible solvent compositions to solubilize poorly soluble compounds for preclinical studies.
Drug Deliv
; 19(5): 239-46, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22656673
4.
Laminin-411 is a vascular ligand for MCAM and facilitates TH17 cell entry into the CNS.
PLoS One
; 7(7): e40443, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22792325