Detalhe da pesquisa
1.
Intrinsic disorder: A term to define the specific physicochemical characteristic of protein conformational heterogeneity.
Mol Cell
; 84(7): 1188-1190, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38579677
2.
Intrinsically disordered proteins in cellular signalling and regulation.
Nat Rev Mol Cell Biol
; 16(1): 18-29, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25531225
3.
Glutamine-rich regions of the disordered CREB transactivation domain mediate dynamic intra- and intermolecular interactions.
Proc Natl Acad Sci U S A
; 120(47): e2313835120, 2023 Nov 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-37971402
4.
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Proc Natl Acad Sci U S A
; 120(39): e2303455120, 2023 09 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-37722054
5.
Multivalency enables unidirectional switch-like competition between intrinsically disordered proteins.
Proc Natl Acad Sci U S A
; 119(3)2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-35012986
6.
Probing the Dissociation Pathway of a Kinetically Labile Transthyretin Mutant.
J Am Chem Soc
; 146(1): 532-542, 2024 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-38134439
7.
Structural and dynamic studies of DNA recognition by NF-κB p50 RHR homodimer using methyl NMR spectroscopy.
Nucleic Acids Res
; 50(12): 7147-7160, 2022 07 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35748866
8.
A phosphorylation-dependent switch in the disordered p53 transactivation domain regulates DNA binding.
Proc Natl Acad Sci U S A
; 118(1)2021 01 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443163
9.
A transthyretin monomer intermediate undergoes local unfolding and transient interaction with oligomers in a kinetically concerted aggregation pathway.
J Biol Chem
; 298(8): 102162, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35724960
10.
Hypersensitive termination of the hypoxic response by a disordered protein switch.
Nature
; 543(7645): 447-451, 2017 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-28273070
11.
From Immunogenic Peptides to Intrinsically Disordered Proteins.
Isr J Chem
; 63(10-11)2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-38454968
12.
An allosteric peptide inhibitor of HIF-1α regulates hypoxia-induced retinal neovascularization.
Proc Natl Acad Sci U S A
; 117(45): 28297-28306, 2020 11 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33106407
13.
Interactions of a Long Noncoding RNA with Domains of NF-κB and IκBα: Implications for the Inhibition of Non-Signal-Related Phosphorylation.
Biochemistry
; 61(5): 367-376, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35171557
14.
Mapping Interactions of the Intrinsically Disordered C-Terminal Regions of Tetrameric p53 by Segmental Isotope Labeling and NMR.
Biochemistry
; 61(23): 2709-2719, 2022 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36380579
15.
Modeling of Hidden Structures Using Sparse Chemical Shift Data from NMR Relaxation Dispersion.
Biophys J
; 120(2): 296-305, 2021 01 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33301748
16.
Role of Active Site Loop Dynamics in Mediating Ligand Release from E. coli Dihydrofolate Reductase.
Biochemistry
; 60(35): 2663-2671, 2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34428034
17.
Thermodynamic Stability and Aggregation Kinetics of EF Helix and EF Loop Variants of Transthyretin.
Biochemistry
; 60(10): 756-764, 2021 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33645214
18.
Characterization of the High-Affinity Fuzzy Complex between the Disordered Domain of the E7 Oncoprotein from High-Risk HPV and the TAZ2 Domain of CBP.
Biochemistry
; 60(51): 3887-3898, 2021 12 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-34905914
19.
Kinetic analysis of the multistep aggregation pathway of human transthyretin.
Proc Natl Acad Sci U S A
; 115(27): E6201-E6208, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29915031
20.
Long-range regulation of p53 DNA binding by its intrinsically disordered N-terminal transactivation domain.
Proc Natl Acad Sci U S A
; 115(48): E11302-E11310, 2018 11 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420502