Detalhe da pesquisa
1.
Dietary flavonoids as cancer prevention agents.
J Environ Sci Health C Environ Carcinog Ecotoxicol Rev
; 29(1): 1-31, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21424974
2.
Pharmacological inhibition of poly(ADP-ribose) polymerase activity down-regulates the expression of syndecan-4 and Id-1 in endothelial cells.
Int J Oncol
; 34(3): 861-72, 2009 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19212692
3.
PARP inhibition or gene deficiency counteracts intraepidermal nerve fiber loss and neuropathic pain in advanced diabetic neuropathy.
Free Radic Biol Med
; 44(6): 972-81, 2008 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17976390
4.
Poly(ADP-ribose) polymerase (PARP) inhibition or PARP-1 gene deletion reduces angiogenesis.
Eur J Cancer
; 43(14): 2124-33, 2007 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-17714938
5.
Inhibition of poly(ADP-ribose) polymerase prevents irinotecan-induced intestinal damage and enhances irinotecan/temozolomide efficacy against colon carcinoma.
FASEB J
; 20(10): 1709-11, 2006 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-16809434
6.
Sirtuin inhibition increases the rate of non-homologous end-joining of DNA double strand breaks.
Acta Biochim Pol
; 54(1): 63-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17311110
7.
Structural optimization of thiol-based inhibitors of glutamate carboxypeptidase II by modification of the P1' side chain.
J Med Chem
; 49(10): 2876-85, 2006 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-16686531
8.
PARG activity mediates intestinal injury induced by splanchnic artery occlusion and reperfusion.
FASEB J
; 19(6): 558-66, 2005 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-15791006
9.
Brain distribution and efficacy as chemosensitizer of an oral formulation of PARP-1 inhibitor GPI 15427 in experimental models of CNS tumors.
Int J Oncol
; 26(2): 415-22, 2005 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-15645126
10.
Treatment with PARP-1 inhibitors, GPI 15427 or GPI 16539, ameliorates intestinal damage in rat models of colitis and shock.
Eur J Pharmacol
; 527(1-3): 163-71, 2005 Dec 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-16310767
11.
Systemic administration of GPI 15427, a novel poly(ADP-ribose) polymerase-1 inhibitor, increases the antitumor activity of temozolomide against intracranial melanoma, glioma, lymphoma.
Clin Cancer Res
; 9(14): 5370-9, 2003 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-14614022
12.
Reaction of Resorcinol with alpha,beta-Unsaturated Ketones.
J Org Chem
; 63(3): 636-641, 1998 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-11672054
13.
Poly(ADP-ribose)polymerase inhibition counteracts renal hypertrophy and multiple manifestations of peripheral neuropathy in diabetic Akita mice.
Int J Mol Med
; 28(4): 629-35, 2011 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-21617845
14.
Poly(ADP-ribose) polymerase (PARP) inhibition counteracts multiple manifestations of kidney disease in long-term streptozotocin-diabetic rat model.
Biochem Pharmacol
; 79(7): 1007-14, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19945439
15.
New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-{alpha}.
Endocrinology
; 151(6): 2547-55, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20357221
16.
Head and neck cancer radiosensitization by the novel poly(ADP-ribose) polymerase inhibitor GPI-15427.
Head Neck
; 32(3): 381-91, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19672867
17.
Reaction of Resorcinol With Acetone.
J Org Chem
; 62(3): 737-742, 1997 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-11671475
18.
Poly(Adenosine 5'-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy.
Endocrinology
; 150(12): 5273-83, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19854869
19.
Poly(ADP-ribose)polymerase inhibition counteracts cataract formation and early retinal changes in streptozotocin-diabetic rats.
Invest Ophthalmol Vis Sci
; 50(4): 1778-90, 2009 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-19098320
20.
Poly(ADP-ribose) glycohydrolase activity mediates post-traumatic inflammatory reaction after experimental spinal cord trauma.
J Pharmacol Exp Ther
; 319(1): 127-38, 2006 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-16825529