Detalhe da pesquisa
1.
Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects.
Cell
; 159(2): 318-32, 2014 Oct 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25303528
2.
Retinol binding protein 4 primes the NLRP3 inflammasome by signaling through Toll-like receptors 2 and 4.
Proc Natl Acad Sci U S A
; 117(49): 31309-31318, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33214151
3.
Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer.
Nat Rev Cancer
; 7(5): 357-69, 2007 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-17446857
4.
New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress.
J Nat Prod
; 74(3): 537-45, 2011 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-21309592
5.
Prevention and treatment of experimental estrogen receptor-negative mammary carcinogenesis by the synthetic triterpenoid CDDO-methyl Ester and the rexinoid LG100268.
Clin Cancer Res
; 14(14): 4556-63, 2008 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18628471
6.
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice.
Cancer Res
; 67(6): 2414-9, 2007 Mar 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-17363558
7.
The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis.
Mol Cancer Ther
; 7(5): 1251-7, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483313
8.
Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
Cancer Res
; 66(4): 2488-94, 2006 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16489057
9.
Methodological Issues in Studying PAHSA Biology: Masking PAHSA Effects.
Cell Metab
; 28(4): 543-546, 2018 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30244974
10.
Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis.
Cell Metab
; 27(2): 419-427.e4, 2018 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29414687
11.
The synthetic triterpenoids, CDDO and CDDO-imidazolide, are potent inducers of heme oxygenase-1 and Nrf2/ARE signaling.
Cancer Res
; 65(11): 4789-98, 2005 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15930299
12.
The synthetic triterpenoid 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole blocks nuclear factor-kappaB activation through direct inhibition of IkappaB kinase beta.
Mol Cancer Ther
; 5(12): 3232-9, 2006 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-17148759
13.
RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance.
Cell Metab
; 19(3): 512-26, 2014 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-24606904
14.
Retinol-binding protein 4 inhibits insulin signaling in adipocytes by inducing proinflammatory cytokines in macrophages through a c-Jun N-terminal kinase- and toll-like receptor 4-dependent and retinol-independent mechanism.
Mol Cell Biol
; 32(10): 2010-9, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22431523
15.
Proteomic analysis shows synthetic oleanane triterpenoid binds to mTOR.
PLoS One
; 6(7): e22862, 2011.
Artigo
em Inglês
| MEDLINE | ID: mdl-21818401
16.
Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice.
Cancer Prev Res (Phila)
; 2(12): 1050-8, 2009 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-19952361
17.
A novel acetylenic tricyclic bis-(cyano enone) potently induces phase 2 cytoprotective pathways and blocks liver carcinogenesis induced by aflatoxin.
Cancer Res
; 68(16): 6727-33, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18701497
18.
Smoothened regulates activator and repressor functions of Hedgehog signaling via two distinct mechanisms.
J Biol Chem
; 281(11): 7237-43, 2006 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-16423832
19.
Limiting effects of RIP140 in estrogen signaling: potential mediation of anti-estrogenic effects of retinoic acid.
J Biol Chem
; 280(9): 7829-35, 2005 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-15632153
20.
Negative feedback at the level of nuclear receptor coregulation. Self-limitation of retinoid signaling by RIP140.
J Biol Chem
; 278(45): 43889-92, 2003 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-14506269