Detalhe da pesquisa
1.
Decitabine cytotoxicity is promoted by dCMP deaminase DCTD and mitigated by SUMO-dependent E3 ligase TOPORS.
EMBO J
; 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38760575
2.
Topoisomerase II-Induced Chromosome Breakage and Translocation Is Determined by Chromosome Architecture and Transcriptional Activity.
Mol Cell
; 75(2): 252-266.e8, 2019 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-31202577
3.
Inactivating TDP2 missense mutation in siblings with congenital abnormalities reminiscent of fanconi anemia.
Hum Genet
; 142(9): 1417-1427, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37558815
4.
Characterization of a novel loss-of-function variant in TDP2 in two adult patients with spinocerebellar ataxia autosomal recessive 23 (SCAR23).
J Hum Genet
; 65(12): 1135-1141, 2020 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-32651480
5.
RAD54L2 counters TOP2-DNA adducts to promote genome stability.
Sci Adv
; 9(49): eadl2108, 2023 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38055822
6.
Large-scale exome sequence analysis identifies sex- and age-specific determinants of obesity.
Cell Genom
; 3(8): 100362, 2023 Aug 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37601970
7.
Combinatorial CRISPR screen identifies fitness effects of gene paralogues.
Nat Commun
; 12(1): 1302, 2021 02 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637726
8.
Untangling trapped topoisomerases with tyrosyl-DNA phosphodiesterases.
DNA Repair (Amst)
; 94: 102900, 2020 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-32653827
9.
Effects of TDP2/VPg Unlinkase Activity on Picornavirus Infections Downstream of Virus Translation.
Viruses
; 12(2)2020 01 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-32023921
10.
Confirming TDP2 mutation in spinocerebellar ataxia autosomal recessive 23 (SCAR23).
Neurol Genet
; 4(4): e262, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30109272
11.
TDP2, TOP2, and SUMO: what is ZATT about?
Cell Res
; 27(12): 1405-1406, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29160298
12.
TDP2 suppresses chromosomal translocations induced by DNA topoisomerase II during gene transcription.
Nat Commun
; 8(1): 233, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28794467