Detalhe da pesquisa
1.
HLTF Promotes Fork Reversal, Limiting Replication Stress Resistance and Preventing Multiple Mechanisms of Unrestrained DNA Synthesis.
Mol Cell
; 78(6): 1237-1251.e7, 2020 06 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32442397
2.
Lead compound profiling for small molecule inhibitors of the REV1-CT/RIR Translesion synthesis Protein-Protein interaction.
Bioorg Med Chem
; 106: 117755, 2024 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38749343
3.
8-Hydroxyquinoline derivatives suppress GLI1-mediated transcription through multiple mechanisms.
Bioorg Chem
; 132: 106387, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36724660
4.
Exploring the physicochemical and antiproliferative properties of biaryl-linked [13]-macrodilactones.
Bioorg Med Chem
; 28(20): 115671, 2020 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33069068
5.
Probing the Protein-Protein Interaction Between the ATRXADD Domain and the Histone H3 Tail.
Molecules
; 25(7)2020 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-32218364
6.
Correction to "An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections".
ACS Cent Sci
; 8(9): 1362, 2022 Sep 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36188352
7.
An Iterative Approach Guides Discovery of the FabI Inhibitor Fabimycin, a Late-Stage Antibiotic Candidate with In Vivo Efficacy against Drug-Resistant Gram-Negative Infections.
ACS Cent Sci
; 8(8): 1145-1158, 2022 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36032774
8.
Structure-based virtual screening identifies an 8-hydroxyquinoline as a small molecule GLI1 inhibitor.
Mol Ther Oncolytics
; 20: 265-276, 2021 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33614910
9.
Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.
ChemMedChem
; 16(7): 1126-1132, 2021 04 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33314657
10.
Inhibition of the translesion synthesis polymerase REV1 exploits replication gaps as a cancer vulnerability.
Sci Adv
; 6(24): eaaz7808, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32577513
11.
Structure-Activity Relationships for Itraconazole-Based Triazolone Analogues as Hedgehog Pathway Inhibitors.
J Med Chem
; 62(8): 3873-3885, 2019 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30896941
12.
A metadynamic approach to understand the recognition mechanism of the histone H3 tail with the ATRXADD domain.
Biochim Biophys Acta Gene Regul Mech
; 1861(6): 594-602, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29730439