Detalhe da pesquisa
1.
KSHV-encoded ORF45 activates human NLRP1 inflammasome.
Nat Immunol
; 23(6): 916-926, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35618833
2.
A conserved PLPLRT/SD motif of STING mediates the recruitment and activation of TBK1.
Nature
; 569(7758): 718-722, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31118511
3.
Structural basis of higher order oligomerization of KSHV inhibitor of cGAS.
Proc Natl Acad Sci U S A
; 119(33): e2200285119, 2022 08 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35939686
4.
The Dengue virus protease NS2B3 cleaves cyclic GMP-AMP synthase to suppress cGAS activation.
J Biol Chem
; 299(3): 102986, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36754281
5.
The SUMO E3 ligase activity of ORF45 determines KSHV lytic replication.
PLoS Pathog
; 18(4): e1010504, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35482828
6.
RSK1 SUMOylation is required for KSHV lytic replication.
PLoS Pathog
; 17(12): e1010123, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34871326
7.
ORF45, a multifunctional immediate early and tegument protein of KSHV.
J Med Virol
; 95(3): e28659, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36905218
8.
Cooperative DNA binding mediated by KicGAS/ORF52 oligomerization allows inhibition of DNA-induced phase separation and activation of cGAS.
Nucleic Acids Res
; 49(16): 9389-9403, 2021 09 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34387695
9.
Development of an ORF45-Derived Peptide To Inhibit the Sustained RSK Activation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
J Virol
; 93(10)2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30842327
10.
Sirtuin 6 Attenuates Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Suppressing Ori-Lyt Activity and Expression of RTA.
J Virol
; 93(7)2019 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30651359
11.
The spring-loaded genome: nucleosome redistributions are widespread, transient, and DNA-directed.
Genome Res
; 24(2): 251-9, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24310001
12.
Kaposi's Sarcoma-Associated Herpesvirus Inhibitor of cGAS (KicGAS), Encoded by ORF52, Is an Abundant Tegument Protein and Is Required for Production of Infectious Progeny Viruses.
J Virol
; 90(11): 5329-5342, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27009954
13.
ORF33 and ORF38 of Kaposi's Sarcoma-Associated Herpesvirus Interact and Are Required for Optimal Production of Infectious Progeny Viruses.
J Virol
; 90(4): 1741-56, 2016 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26637455
14.
Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36.
J Virol
; 90(13): 5953-5964, 2016 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27099309
15.
Phosphoproteomic Analysis of KSHV-Infected Cells Reveals Roles of ORF45-Activated RSK during Lytic Replication.
PLoS Pathog
; 11(7): e1004993, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26133373
16.
Mono-ubiquitylated ORF45 Mediates Association of KSHV Particles with Internal Lipid Rafts for Viral Assembly and Egress.
PLoS Pathog
; 11(12): e1005332, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26650119
17.
ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus.
J Virol
; 89(13): 6895-906, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-25903346
18.
A survey of the interactome of Kaposi's sarcoma-associated herpesvirus ORF45 revealed its binding to viral ORF33 and cellular USP7, resulting in stabilization of ORF33 that is required for production of progeny viruses.
J Virol
; 89(9): 4918-31, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25694600
19.
Activation of p90 ribosomal S6 kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus is critical for optimal production of infectious viruses.
J Virol
; 89(1): 195-207, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320298
20.
ORF45 of Kaposi's sarcoma-associated herpesvirus inhibits phosphorylation of interferon regulatory factor 7 by IKKε and TBK1 as an alternative substrate.
J Virol
; 86(18): 10162-72, 2012 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-22787218