Pesquisa | Portal de Pesquisa da BVS Enfermagem

1.

Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity.

van Galen, Peter; Hovestadt, Volker; Wadsworth Ii, Marc H; Hughes, Travis K; Griffin, Gabriel K; Battaglia, Sofia; Verga, Julia A; Stephansky, Jason; Pastika, Timothy J; Lombardi Story, Jennifer; Pinkus, Geraldine S; Pozdnyakova, Olga; Galinsky, Ilene; Stone, Richard M; Graubert, Timothy A; Shalek, Alex K; Aster, Jon C; Lane, Andrew A; Bernstein, Bradley E.

Cell ; 176(6): 1265-1281.e24, 2019 03 07.

Artigo em Inglês | MEDLINE | ID: mdl-30827681

2.

Targetable leukaemia dependency on noncanonical PI3KÎ³ signalling.

Luo, Qingyu; Raulston, Evangeline G; Prado, Miguel A; Wu, Xiaowei; Gritsman, Kira; Whalen, Karley S; Yan, Kezhi; Booth, Christopher A G; Xu, Ran; van Galen, Peter; Doench, John G; Shimony, Shai; Long, Henry W; Neuberg, Donna S; Paulo, Joao A; Lane, Andrew A.

Nature ; 2024 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-38720074

3.

Deciphering cell states and genealogies of human haematopoiesis.

Weng, Chen; Yu, Fulong; Yang, Dian; Poeschla, Michael; Liggett, L Alexander; Jones, Matthew G; Qiu, Xiaojie; Wahlster, Lara; Caulier, Alexis; Hussmann, Jeffrey A; Schnell, Alexandra; Yost, Kathryn E; Koblan, Luke W; Martin-Rufino, Jorge D; Min, Joseph; Hammond, Alessandro; Ssozi, Daniel; Bueno, Raphael; Mallidi, Hari; Kreso, Antonia; Escabi, Javier; Rideout, William M; Jacks, Tyler; Hormoz, Sahand; van Galen, Peter; Weissman, Jonathan S; Sankaran, Vijay G.

Nature ; 627(8003): 389-398, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38253266

4.

Ultraviolet radiation shapes dendritic cell leukaemia transformation in the skin.

Griffin, Gabriel K; Booth, Christopher A G; Togami, Katsuhiro; Chung, Sun Sook; Ssozi, Daniel; Verga, Julia A; Bouyssou, Juliette M; Lee, Yoke Seng; Shanmugam, Vignesh; Hornick, Jason L; LeBoeuf, Nicole R; Morgan, Elizabeth A; Bernstein, Bradley E; Hovestadt, Volker; van Galen, Peter; Lane, Andrew A.

Nature ; 618(7966): 834-841, 2023 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-37286599

5.

Association of clonal hematopoiesis with chronic obstructive pulmonary disease.

Miller, Peter G; Qiao, Dandi; Rojas-Quintero, Joselyn; Honigberg, Michael C; Sperling, Adam S; Gibson, Christopher J; Bick, Alexander G; Niroula, Abhishek; McConkey, Marie E; Sandoval, Brittany; Miller, Brian C; Shi, Weiwei; Viswanathan, Kaushik; Leventhal, Matthew; Werner, Lillian; Moll, Matthew; Cade, Brian E; Barr, R Graham; Correa, Adolfo; Cupples, L Adrienne; Gharib, Sina A; Jain, Deepti; Gogarten, Stephanie M; Lange, Leslie A; London, Stephanie J; Manichaikul, Ani; O'Connor, George T; Oelsner, Elizabeth C; Redline, Susan; Rich, Stephen S; Rotter, Jerome I; Ramachandran, Vasan; Yu, Bing; Sholl, Lynette; Neuberg, Donna; Jaiswal, Siddhartha; Levy, Bruce D; Owen, Caroline A; Natarajan, Pradeep; Silverman, Edwin K; van Galen, Peter; Tesfaigzi, Yohannes; Cho, Michael H; Ebert, Benjamin L.

Blood ; 139(3): 357-368, 2022 01 20.

Artigo em Inglês | MEDLINE | ID: mdl-34855941

6.

A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes.

van Galen, Peter; Viny, Aaron D; Ram, Oren; Ryan, Russell J H; Cotton, Matthew J; Donohue, Laura; Sievers, Cem; Drier, Yotam; Liau, Brian B; Gillespie, Shawn M; Carroll, Kaitlin M; Cross, Michael B; Levine, Ross L; Bernstein, Bradley E.

Mol Cell ; 61(1): 170-80, 2016 Jan 07.

Artigo em Inglês | MEDLINE | ID: mdl-26687680

7.

WAT3R: recovery of T-cell receptor variable regions from 3' single-cell RNA-sequencing.

Ainciburu, Marina; Morgan, Duncan M; DePasquale, Erica A K; Love, J Christopher; Prósper, Felipe; van Galen, Peter.

Bioinformatics ; 38(14): 3645-3647, 2022 07 11.

Artigo em Inglês | MEDLINE | ID: mdl-35674381

8.

Single-Cell RNA Sequencing to Disentangle the Blood System.

Acosta, Jean; Ssozi, Daniel; van Galen, Peter.

Arterioscler Thromb Vasc Biol ; 41(3): 1012-1018, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33441024

9.

A stemness screen reveals C3orf54/INKA1 as a promoter of human leukemia stem cell latency.

Kaufmann, Kerstin B; Garcia-Prat, Laura; Liu, Qiang; Ng, Stanley W K; Takayanagi, Shin-Ichiro; Mitchell, Amanda; Wienholds, Erno; van Galen, Peter; Cumbaa, Christian A; Tsay, Mike J; Pastrello, Chiara; Wagenblast, Elvin; Krivdova, Gabriela; Minden, Mark D; Lechman, Eric R; Zandi, Sasan; Jurisica, Igor; Wang, Jean C Y; Xie, Stephanie Z; Dick, John E.

Blood ; 133(20): 2198-2211, 2019 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-30796022

10.

Mutation signatures reveal clonal evolution.

Lee, Yoke Seng; van Galen, Peter.

Blood ; 141(19): 2292-2293, 2023 05 11.

Artigo em Inglês | MEDLINE | ID: mdl-37166926

11.

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

van Galen, Peter; Kreso, Antonija; Mbong, Nathan; Kent, David G; Fitzmaurice, Timothy; Chambers, Joseph E; Xie, Stephanie; Laurenti, Elisa; Hermans, Karin; Eppert, Kolja; Marciniak, Stefan J; Goodall, Jane C; Green, Anthony R; Wouters, Bradly G; Wienholds, Erno; Dick, John E.

Nature ; 510(7504): 268-72, 2014 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-24776803

12.

Renewing your HBO1 subscription.

Najm, Fadi J; van Galen, Peter.

Blood ; 139(6): 802-804, 2022 02 10.

Artigo em Inglês | MEDLINE | ID: mdl-35142852

13.

Plasticity and immune evasion in childhood ALL.

DePasquale, Erica A K; van Galen, Peter.

Blood ; 139(14): 2096-2097, 2022 04 07.

Artigo em Inglês | MEDLINE | ID: mdl-35389444

14.

EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

Renneville, Aline; Van Galen, Peter; Canver, Matthew C; McConkey, Marie; Krill-Burger, John M; Dorfman, David M; Holson, Edward B; Bernstein, Bradley E; Orkin, Stuart H; Bauer, Daniel E; Ebert, Benjamin L.

Blood ; 126(16): 1930-9, 2015 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-26320100

15.

Spectral Flow Cytometry Methods and Pipelines for Comprehensive Immunoprofiling of Human Peripheral Blood and Bone Marrow.

Spasic, Milos; Ogayo, Esther R; Parsons, Adrienne M; Mittendorf, Elizabeth A; van Galen, Peter; McAllister, Sandra S.

Cancer Res Commun ; 4(3): 895-910, 2024 Mar 25.

Artigo em Inglês | MEDLINE | ID: mdl-38466569

16.

Multiomic Profiling of Human Clonal Hematopoiesis Reveals Genotype and Cell-Specific Inflammatory Pathway Activation.

Heimlich, Jonathan Brett; Bhat, Pawan; Parker, Alyssa; Jenkins, Matthew T; Vlasschaert, Caitlyn; Ulloa, Jessica; Van Amburg, Joseph; Potts, Chad R; Olson, Sydney; Silver, Alexander J; Ahmad, Ayesha; Sharber, Brian; Brown, Donovan; Hu, Ningning; van Galen, Peter; Savona, Michael R; Bick, Alexander G; Ferrell, Paul Brent.

Blood Adv ; 2024 Mar 20.

Artigo em Inglês | MEDLINE | ID: mdl-38507736

17.

Combination of pantothenamides with vanin inhibitors as a novel antibiotic strategy against gram-positive bacteria.

Jansen, Patrick A M; Hermkens, Pedro H H; Zeeuwen, Patrick L J M; Botman, Peter N M; Blaauw, Richard H; Burghout, Peter; van Galen, Peter M; Mouton, Johan W; Rutjes, Floris P J T; Schalkwijk, Joost.

Antimicrob Agents Chemother ; 57(10): 4794-800, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23877685

18.

Chromatin complex dependencies reveal targeting opportunities in leukemia.

Najm, Fadi J; DeWeirdt, Peter; Moore, Molly M; Bevill, Samantha M; El Farran, Chadi A; Macias, Kevin A; Hegde, Mudra; Waterbury, Amanda L; Liau, Brian B; van Galen, Peter; Doench, John G; Bernstein, Bradley E.

Nat Commun ; 14(1): 448, 2023 01 27.

Artigo em Inglês | MEDLINE | ID: mdl-36707513

19.

"Candidatus Hydrogenisulfobacillus filiaventi" strain R50 gen. nov. sp. nov., a highly efficient producer of extracellular organic compounds from H₂ and CO₂.

Hogendoorn, Carmen; Pol, Arjan; de Graaf, Rob; White, Paul B; Mesman, Rob; van Galen, Peter M; van Alen, Theo A; Cremers, Geert; Jansen, Robert S; Jetten, Mike S M; Op den Camp, Huub J M.

Front Microbiol ; 14: 1151097, 2023.

Artigo em Inglês | MEDLINE | ID: mdl-37032882

20.

CALR-mutated cells are vulnerable to combined inhibition of the proteasome and the endoplasmic reticulum stress response.

Jutzi, Jonas S; Marneth, Anna E; Jiménez-Santos, María José; Hem, Jessica; Guerra-Moreno, Angel; Rolles, Benjamin; Bhatt, Shruti; Myers, Samuel A; Carr, Steven A; Hong, Yuning; Pozdnyakova, Olga; van Galen, Peter; Al-Shahrour, Fátima; Nam, Anna S; Mullally, Ann.

Leukemia ; 37(2): 359-369, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36473980

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