Detalhe da pesquisa
1.
Vaccination With Detoxified Leukocidin AB Reduces Bacterial Load in a Staphylococcus aureus Minipig Deep Surgical Wound Infection Model.
J Infect Dis
; 225(8): 1460-1470, 2022 04 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-33895843
2.
A randomized phase 1/2a trial of ExPEC10V vaccine in adults with a history of UTI.
NPJ Vaccines
; 9(1): 106, 2024 Jun 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38877036
3.
Nonclinical vaccine safety evaluation: advantages of continuous temperature monitoring using abdominally implanted data loggers.
J Appl Toxicol
; 33(6): 521-6, 2013 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22407801
4.
Safety, Reactogenicity, Immunogenicity, and Dose Selection of 10-Valent Extraintestinal Pathogenic Escherichia coli Bioconjugate Vaccine (VAC52416) in Adults Aged 60-85 Years in a Randomized, Multicenter, Interventional, First-in-Human, Phase 1/2a Study.
Open Forum Infect Dis
; 10(8): ofad417, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37608916
5.
Colonization with Escherichia coli ST131-H30R (H30R) Corresponds with Increased Serum Anti-O25 IgG Levels and Decreased TNFα and IL-10 Responsiveness to H30R.
Pathogens
; 12(4)2023 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37111489
6.
Neutralizing antibodies elicited by a novel detoxified pneumolysin derivative, PlyD1, provide protection against both pneumococcal infection and lung injury.
Infect Immun
; 80(6): 2212-20, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22473606
7.
Is a single dose of meningococcal serogroup C conjugate vaccine sufficient for protection? experience from the Netherlands.
BMC Infect Dis
; 12: 35, 2012 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22316426
8.
Carriage of Streptococcus pneumoniae 3 years after start of vaccination program, the Netherlands.
Emerg Infect Dis
; 17(4): 584-91, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21470445
9.
Lower immunoglobulin G antibody responses to pneumococcal conjugate vaccination at the age of 2 years after previous nasopharyngeal carriage of Streptococcus pneumoniae.
J Pediatr
; 159(6): 965-70.e1, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21813135
10.
Next-generation outer membrane vesicle vaccines against Neisseria meningitidis based on nontoxic LPS mutants.
Hum Vaccin
; 7(8): 886-90, 2011 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-21785281
11.
The structure of Neisseria meningitidis lipid A determines outcome in experimental meningococcal disease.
Infect Immun
; 78(7): 3177-86, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20439476
12.
Safety and immunogenicity of a vaccine for extra-intestinal pathogenic Escherichia coli (ESTELLA): a phase 2 randomised controlled trial.
Lancet Infect Dis
; 19(6): 631-640, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31079947
13.
Increasing FIM2/3 antigen-content improves efficacy of Bordetella pertussis vaccines in mice in vivo without altering vaccine-induced human reactogenicity biomarkers in vitro.
Vaccine
; 37(1): 80-89, 2019 01 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30478007
14.
Meningococcal B vaccine development and evaluation of efficacy.
Hum Vaccin
; 4(2): 158-61, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18388494
15.
Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1.
PLoS One
; 13(3): e0193650, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29509778
16.
Safety, tolerability and immunogenicity of the ExPEC4V (JNJ-63871860) vaccine for prevention of invasive extraintestinal pathogenic Escherichia coli disease: A phase 1, randomized, double-blind, placebo-controlled study in healthy Japanese participants.
Hum Vaccin Immunother
; 14(9): 2150-2157, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29771596
17.
Development and Qualification of an Opsonophagocytic Killing Assay To Assess Immunogenicity of a Bioconjugated Escherichia coli Vaccine.
Clin Vaccine Immunol
; 24(12)2017 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-28971965
18.
Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial.
Lancet Infect Dis
; 17(5): 528-537, 2017 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28238601
19.
CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity.
Crit Care
; 10(1): R33, 2006 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-16507164
20.
A Meningococcal Outer Membrane Vesicle Vaccine Incorporating Genetically Attenuated Endotoxin Dissociates Inflammation from Immunogenicity.
Front Immunol
; 7: 562, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-28008331