Detalhe da pesquisa
1.
Antibody-Drug Conjugates (ADCs) Derived from Interchain Cysteine Cross-Linking Demonstrate Improved Homogeneity and Other Pharmacological Properties over Conventional Heterogeneous ADCs.
Mol Pharm
; 12(11): 3986-98, 2015 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26393951
2.
Myeloid and dendritic cells enhance therapeutics-induced cytokine release syndrome features in humanized BRGSF-HIS preclinical model.
Front Immunol
; 15: 1357716, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38384461
3.
VISTA checkpoint inhibition by pH-selective antibody SNS-101 with optimized safety and pharmacokinetic profiles enhances PD-1 response.
Nat Commun
; 15(1): 2917, 2024 Apr 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38575562
4.
Conditionally Active, pH-Sensitive Immunoregulatory Antibodies Targeting VISTA and CTLA-4 Lead an Emerging Class of Cancer Therapeutics.
Antibodies (Basel)
; 12(3)2023 Aug 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37753969
5.
Combination of ZEN-3694 with CDK4/6 inhibitors reverses acquired resistance to CDK4/6 inhibitors in ER-positive breast cancer.
Cancer Gene Ther
; 29(6): 859-869, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34385584
6.
Design and Synthesis of LM146, a Potent Inhibitor of PB1 with an Improved Selectivity Profile over SMARCA2.
ACS Omega
; 6(33): 21327-21338, 2021 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-34471737
7.
Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine.
J Med Chem
; 61(18): 8202-8211, 2018 09 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-30165024
8.
CD98-Mediated Adhesive Signaling Enables the Establishment and Propagation of Acute Myelogenous Leukemia.
Cancer Cell
; 30(5): 792-805, 2016 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-27908736