Detalhe da pesquisa
1.
The probabilistic model of Alzheimer disease: the amyloid hypothesis revised.
Nat Rev Neurosci
; 23(1): 53-66, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34815562
2.
Amyloid-ß-independent regulators of tau pathology in Alzheimer disease.
Nat Rev Neurosci
; 21(1): 21-35, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31780819
3.
SKIP-HOPS recruits TBC1D15 for a Rab7-to-Arl8b identity switch to control late endosome transport.
EMBO J
; 39(6): e102301, 2020 03 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32080880
4.
APOE and immunity: Research highlights.
Alzheimers Dement
; 19(6): 2677-2696, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36975090
5.
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.
J Biol Chem
; 290(51): 30280-90, 2015 Dec 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-26463206
6.
Small regulators, major consequences - Ca²âº and cholesterol at the endosome-ER interface.
J Cell Sci
; 127(Pt 5): 929-38, 2014 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24554437
7.
LMP1 association with CD63 in endosomes and secretion via exosomes limits constitutive NF-κB activation.
EMBO J
; 30(11): 2115-29, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21527913
8.
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
J Cell Sci
; 126(Pt 15): 3462-74, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23729732
9.
An inside job: New roles for ApoE at the lipid droplet.
J Cell Biol
; 223(4)2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38466168
10.
Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1.
J Lipid Res
; 54(8): 2153-2165, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23709693
11.
Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments.
Cell Mol Life Sci
; 69(12): 2075-89, 2012 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-22261744
12.
Tau biomarkers in Alzheimer's disease: towards implementation in clinical practice and trials.
Lancet Neurol
; 21(8): 726-734, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35643092
13.
A reference human induced pluripotent stem cell line for large-scale collaborative studies.
Cell Stem Cell
; 29(12): 1685-1702.e22, 2022 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459969
14.
Cholesterol and Alzheimer's Disease; From Risk Genes to Pathological Effects.
Front Aging Neurosci
; 13: 690372, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34248607
15.
Cholesterol-lowering drugs reduce APP processing to Aß by inducing APP dimerization.
Mol Biol Cell
; 32(3): 247-259, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33296223
16.
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-ß in iPSC-Derived Alzheimer's Disease Neurons.
Cell Stem Cell
; 24(3): 363-375.e9, 2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30686764
17.
Defective Transcytosis of APP and Lipoproteins in Human iPSC-Derived Neurons with Familial Alzheimer's Disease Mutations.
Cell Rep
; 17(3): 759-773, 2016 10 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27732852
18.
Cellular functions of the amyloid precursor protein from development to dementia.
Dev Cell
; 32(4): 502-15, 2015 Feb 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-25710536
19.
GPR43 Potentiates ß-Cell Function in Obesity.
Diabetes
; 64(9): 3203-17, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26023106
20.
Stuck in traffic: an emerging theme in diseases of the nervous system.
Trends Neurosci
; 37(2): 66-76, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24411104