ABSTRACT
In December 2019, a cluster of atypical pneumonia cases were reported in Wuhan, China, and a novel coronavirus elucidated as the aetiologic agent. Although most initial cases occurred in China, the disease, termed coronavirus disease 2019, has become a pandemic and continues to spread rapidly with human-to-human transmission in many countries. This is the third novel coronavirus outbreak in the last two decades and presents an ensuing healthcare resource burden that threatens to overwhelm available healthcare resources. A study of the initial Chinese response has shown that there is a significant positive association between coronavirus disease 2019 mortality and healthcare resource burden. Based on the Chinese experience, some 19% of coronavirus disease 2019 cases develop severe or critical disease. This results in a need for adequate preparation and mobilisation of critical care resources to anticipate and adapt to a surge in coronavirus disease 2019 case-load in order to mitigate morbidity and mortality. In this article, we discuss some of the peri-operative and critical care resource planning considerations and management strategies employed in a tertiary academic medical centre in Singapore in response to the coronavirus disease 2019 outbreak.
Subject(s)
Academic Medical Centers , Coronavirus Infections/therapy , Critical Care/methods , Perioperative Care/methods , Pneumonia, Viral/therapy , Practice Guidelines as Topic , Betacoronavirus , COVID-19 , Humans , Pandemics , SARS-CoV-2 , SingaporeABSTRACT
A retrospective study of 2526 autopsy cases was done in order to find out the pattern of systemic fungal infections. The autopsy records were reviewed for case histories, gross and histological findings. The histological sections from cases showing evidence of fungalo infections were reviewed. The fungal infections were found in 28 cases. Of these 11 (93.29 percent) were aspergillosis, 8 (28.27 percent) were mucormyosis, 6 (21.43 percent) were monilial infections and 3 (10.71 percent) were monilial infections and 3 (10.71 percent) were cryptococcosis. The incidence of systemic fungal infection was 1.11 percent. The most common type of fungal infection was aspergillosis. The maximum number of fungal infection was seen in the respiratory system. The fungal infections presented as opportunistic infections in all but one case. The metabolic disturbance was the most frequent predisposing condition for systemic fungal infections.
Subject(s)
Cause of Death , Developing Countries , Mycoses/mortality , Autopsy , Cross-Sectional Studies , Humans , Incidence , India/epidemiologySubject(s)
Meningioma/pathology , Spinal Neoplasms/pathology , Humans , Lymph Nodes/pathology , Lymphatic Metastasis , Male , Middle AgedSubject(s)
Salivary Gland Neoplasms/pathology , Adult , Female , Humans , Male , Middle Aged , Salivary Gland Neoplasms/classificationSubject(s)
Salivary Gland Neoplasms/epidemiology , Adolescent , Adult , Aged , Child , Female , Humans , Male , Middle AgedSubject(s)
Diphtheria/diagnosis , Lip Diseases/diagnosis , Skin Diseases, Infectious/diagnosis , Child , Humans , MaleSubject(s)
Accidents, Traffic , Embolism, Fat/etiology , Adolescent , Adult , Aged , Child , Child, Preschool , Embolism, Fat/epidemiology , Embolism, Fat/pathology , Humans , Kidney/pathology , Lung/pathology , Middle AgedABSTRACT
A thirtyseven years old Hindu male of borderline lepromatous leprosy with reactions in the form of silvery white scales all over the body with scarring at places and greasy crusted lesion on the cheek further developed pustular reaction, after giving dapsone for a week, is reported.