Search details
1.
Quantitative Proteomics for Translational Pharmacology and Precision Medicine: State of The Art and Future Outlook.
Drug Metab Dispos
; 2024 May 31.
Article
in English
| MEDLINE | ID: mdl-38821856
2.
Examining Physiologically Based Pharmacokinetic Model Assumptions for Cross-Tissue Similarity of Activity per Unit of Enzyme: The Case Example of Uridine 5'-Diphosphate Glucuronosyltransferase.
Drug Metab Dispos
; 50(8): 1119-1125, 2022 08.
Article
in English
| MEDLINE | ID: mdl-35636771
3.
Label-Free but Still Constrained: Assessment of Global Proteomic Strategies for the Quantification of Hepatic Enzymes and Transporters.
Drug Metab Dispos
; 50(6): 762-769, 2022 06.
Article
in English
| MEDLINE | ID: mdl-35307650
4.
Proteomics of colorectal cancer liver metastasis: A quantitative focus on drug elimination and pharmacodynamics effects.
Br J Clin Pharmacol
; 88(4): 1811-1823, 2022 02.
Article
in English
| MEDLINE | ID: mdl-34599518
5.
Proteomic Quantification of Changes in Abundance of Drug-Metabolizing Enzymes and Drug Transporters in Human Liver Cirrhosis: Different Methods, Similar Outcomes.
Drug Metab Dispos
; 49(8): 610-618, 2021 08.
Article
in English
| MEDLINE | ID: mdl-34045218
6.
Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis.
Drug Metab Dispos
; 49(7): 563-571, 2021 07.
Article
in English
| MEDLINE | ID: mdl-33980603
7.
Label-Free Quantitative Proteomics and Substrate-Based Mass Spectrometry Imaging of Xenobiotic Metabolizing Enzymes in Ex Vivo Human Skin and a Human Living Skin Equivalent Model.
Drug Metab Dispos
; 49(1): 39-52, 2021 01.
Article
in English
| MEDLINE | ID: mdl-33139459
8.
Non-uniformity of Changes in Drug-Metabolizing Enzymes and Transporters in Liver Cirrhosis: Implications for Drug Dosage Adjustment.
Mol Pharm
; 18(9): 3563-3577, 2021 09 06.
Article
in English
| MEDLINE | ID: mdl-34428046
9.
Scaling Factors for Clearance in Adult Liver Cirrhosis.
Drug Metab Dispos
; 48(12): 1271-1282, 2020 12.
Article
in English
| MEDLINE | ID: mdl-32978222
10.
Quantitative Proteomics of Clinically Relevant Drug-Metabolizing Enzymes and Drug Transporters and Their Intercorrelations in the Human Small Intestine.
Drug Metab Dispos
; 48(4): 245-254, 2020 04.
Article
in English
| MEDLINE | ID: mdl-31959703
11.
Proteomic characterisation of drug metabolising enzymes and drug transporters in pig liver.
Xenobiotica
; 50(10): 1208-1219, 2020 Oct.
Article
in English
| MEDLINE | ID: mdl-32352885
12.
Proteomic Quantification of Human Blood-Brain Barrier SLC and ABC Transporters in Healthy Individuals and Dementia Patients.
Mol Pharm
; 16(3): 1220-1233, 2019 03 04.
Article
in English
| MEDLINE | ID: mdl-30735053
13.
Quantification of Proteins Involved in Drug Metabolism and Disposition in the Human Liver Using Label-Free Global Proteomics.
Mol Pharm
; 16(2): 632-647, 2019 02 04.
Article
in English
| MEDLINE | ID: mdl-30608694
14.
Identification and quantification of blood-brain barrier transporters in isolated rat brain microvessels.
J Neurochem
; 146(6): 670-685, 2018 09.
Article
in English
| MEDLINE | ID: mdl-29675872
15.
Data Generated by Quantitative Liquid Chromatography-Mass Spectrometry Proteomics Are Only the Start and Not the Endpoint: Optimization of Quantitative Concatemer-Based Measurement of Hepatic Uridine-5'-Diphosphate-Glucuronosyltransferase Enzymes with Reference to Catalytic Activity.
Drug Metab Dispos
; 46(6): 805-812, 2018 06.
Article
in English
| MEDLINE | ID: mdl-29581103
16.
Quantification of the proteins of the bacterial ribosome using QconCAT technology.
J Proteome Res
; 13(3): 1211-22, 2014 Mar 07.
Article
in English
| MEDLINE | ID: mdl-24494973
17.
Complementarity of two proteomic data analysis tools in the identification of drug-metabolising enzymes and transporters in human liver.
Mol Omics
; 20(2): 115-127, 2024 Feb 19.
Article
in English
| MEDLINE | ID: mdl-37975521
18.
Dealing With Variable Drug Exposure Due to Variable Hepatic Metabolism: A Proof-of-Concept Application of Liquid Biopsy in Renal Impairment.
Clin Pharmacol Ther
; 2024 May 13.
Article
in English
| MEDLINE | ID: mdl-38738484
19.
Proteomic quantification of receptor tyrosine kinases involved in the development and progression of colorectal cancer liver metastasis.
Front Oncol
; 13: 1010563, 2023.
Article
in English
| MEDLINE | ID: mdl-36890818
20.
Toward systems-informed models for biologics disposition: covariates of the abundance of the neonatal Fc Receptor (FcRn) in human tissues and implications for pharmacokinetic modelling.
Eur J Pharm Sci
; 182: 106375, 2023 Mar 01.
Article
in English
| MEDLINE | ID: mdl-36626943