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1.

The Genetic Basis of Metabolic Disease.

Barroso, Inês; McCarthy, Mark I.

Cell ; 177(1): 146-161, 2019 03 21.

Article in English | MEDLINE | ID: mdl-30901536

2.

Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance.

van der Klaauw, Agatha A; Croizier, Sophie; Mendes de Oliveira, Edson; Stadler, Lukas K J; Park, Soyoung; Kong, Youxin; Banton, Matthew C; Tandon, Panna; Hendricks, Audrey E; Keogh, Julia M; Riley, Susanna E; Papadia, Sofia; Henning, Elana; Bounds, Rebecca; Bochukova, Elena G; Mistry, Vanisha; O'Rahilly, Stephen; Simerly, Richard B; Minchin, James E N; Barroso, Inês; Jones, E Yvonne; Bouret, Sebastien G; Farooqi, I Sadaf.

Cell ; 176(4): 729-742.e18, 2019 02 07.

Article in English | MEDLINE | ID: mdl-30661757

3.

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.

Pearce, Laura R; Atanassova, Neli; Banton, Matthew C; Bottomley, Bill; van der Klaauw, Agatha A; Revelli, Jean-Pierre; Hendricks, Audrey; Keogh, Julia M; Henning, Elana; Doree, Deon; Jeter-Jones, Sabrina; Garg, Sumedha; Bochukova, Elena G; Bounds, Rebecca; Ashford, Sofie; Gayton, Emma; Hindmarsh, Peter C; Shield, Julian P H; Crowne, Elizabeth; Barford, David; Wareham, Nick J; O'Rahilly, Stephen; Murphy, Michael P; Powell, David R; Barroso, Ines; Farooqi, I Sadaf.

Cell ; 155(4): 765-77, 2013 Nov 07.

Article in English | MEDLINE | ID: mdl-24209692

4.

Genomics of disease risk in globally diverse populations.

Gurdasani, Deepti; Barroso, Inês; Zeggini, Eleftheria; Sandhu, Manjinder S.

Nat Rev Genet ; 20(9): 520-535, 2019 09.

Article in English | MEDLINE | ID: mdl-31235872

5.

Author Correction: Genomics of disease risk in globally diverse populations.

Gurdasani, Deepti; Barroso, Inês; Zeggini, Eleftheria; Sandhu, Manjinder S.

Nat Rev Genet ; 20(9): 562, 2019 Sep.

Article in English | MEDLINE | ID: mdl-31270439

6.

Obesity-Associated GNAS Mutations and the Melanocortin Pathway.

Mendes de Oliveira, Edson; Keogh, Julia M; Talbot, Fleur; Henning, Elana; Ahmed, Rachel; Perdikari, Aliki; Bounds, Rebecca; Wasiluk, Natalia; Ayinampudi, Vikram; Barroso, Inês; Mokrosinski, Jacek; Jyothish, Deepthi; Lim, Sharon; Gupta, Sanjay; Kershaw, Melanie; Matei, Cristina; Partha, Praveen; Randell, Tabitha; McAulay, Antoinette; Wilson, Louise C; Cheetham, Tim; Crowne, Elizabeth C; Clayton, Peter; Farooqi, I Sadaf.

N Engl J Med ; 385(17): 1581-1592, 2021 10 21.

Article in English | MEDLINE | ID: mdl-34614324

7.

Predicting novel candidate human obesity genes and their site of action by systematic functional screening in Drosophila.

Agrawal, Neha; Lawler, Katherine; Davidson, Catherine M; Keogh, Julia M; Legg, Robert; Barroso, Inês; Farooqi, I Sadaf; Brand, Andrea H.

PLoS Biol ; 19(11): e3001255, 2021 11.

Article in English | MEDLINE | ID: mdl-34748544

8.

The impact of population-level HbA_1c screening on reducing diabetes diagnostic delay in middle-aged adults: a UK Biobank analysis.

Young, Katherine G; McGovern, Andrew P; Barroso, Inês; Hattersley, Andrew T; Jones, Angus G; Shields, Beverley M; Thomas, Nicholas J; Dennis, John M.

Diabetologia ; 66(2): 300-309, 2023 02.

Article in English | MEDLINE | ID: mdl-36411396

9.

The influence of rare variants in circulating metabolic biomarkers.

Riveros-Mckay, Fernando; Oliver-Williams, Clare; Karthikeyan, Savita; Walter, Klaudia; Kundu, Kousik; Ouwehand, Willem H; Roberts, David; Di Angelantonio, Emanuele; Soranzo, Nicole; Danesh, John; Wheeler, Eleanor; Zeggini, Eleftheria; Butterworth, Adam S; Barroso, Inês.

PLoS Genet ; 16(3): e1008605, 2020 03.

Article in English | MEDLINE | ID: mdl-32150548

10.

Novel loci for childhood body mass index and shared heritability with adult cardiometabolic traits.

Vogelezang, Suzanne; Bradfield, Jonathan P; Ahluwalia, Tarunveer S; Curtin, John A; Lakka, Timo A; Grarup, Niels; Scholz, Markus; van der Most, Peter J; Monnereau, Claire; Stergiakouli, Evie; Heiskala, Anni; Horikoshi, Momoko; Fedko, Iryna O; Vilor-Tejedor, Natalia; Cousminer, Diana L; Standl, Marie; Wang, Carol A; Viikari, Jorma; Geller, Frank; Íñiguez, Carmen; Pitkänen, Niina; Chesi, Alessandra; Bacelis, Jonas; Yengo, Loic; Torrent, Maties; Ntalla, Ioanna; Helgeland, Øyvind; Selzam, Saskia; Vonk, Judith M; Zafarmand, Mohammed H; Heude, Barbara; Farooqi, Ismaa Sadaf; Alyass, Akram; Beaumont, Robin N; Have, Christian T; Rzehak, Peter; Bilbao, Jose Ramon; Schnurr, Theresia M; Barroso, Inês; Bønnelykke, Klaus; Beilin, Lawrence J; Carstensen, Lisbeth; Charles, Marie-Aline; Chawes, Bo; Clément, Karine; Closa-Monasterolo, Ricardo; Custovic, Adnan; Eriksson, Johan G; Escribano, Joaquin; Groen-Blokhuis, Maria.

PLoS Genet ; 16(10): e1008718, 2020 10.

Article in English | MEDLINE | ID: mdl-33045005

11.

A Specific CNOT1 Mutation Results in a Novel Syndrome of Pancreatic Agenesis and Holoprosencephaly through Impaired Pancreatic and Neurological Development.

De Franco, Elisa; Watson, Rachel A; Weninger, Wolfgang J; Wong, Chi C; Flanagan, Sarah E; Caswell, Richard; Green, Angela; Tudor, Catherine; Lelliott, Christopher J; Geyer, Stefan H; Maurer-Gesek, Barbara; Reissig, Lukas F; Lango Allen, Hana; Caliebe, Almuth; Siebert, Reiner; Holterhus, Paul Martin; Deeb, Asma; Prin, Fabrice; Hilbrands, Robert; Heimberg, Harry; Ellard, Sian; Hattersley, Andrew T; Barroso, Inês.

Am J Hum Genet ; 104(5): 985-989, 2019 05 02.

Article in English | MEDLINE | ID: mdl-31006513

12.

Genetic architecture of human thinness compared to severe obesity.

Riveros-McKay, Fernando; Mistry, Vanisha; Bounds, Rebecca; Hendricks, Audrey; Keogh, Julia M; Thomas, Hannah; Henning, Elana; Corbin, Laura J; O'Rahilly, Stephen; Zeggini, Eleftheria; Wheeler, Eleanor; Barroso, Inês; Farooqi, I Sadaf.

PLoS Genet ; 15(1): e1007603, 2019 01.

Article in English | MEDLINE | ID: mdl-30677029

13.

Controlled Release of Epigenetically-Enhanced Extracellular Vesicles from a GelMA/Nanoclay Composite Hydrogel to Promote Bone Repair.

Man, Kenny; Barroso, Inês A; Brunet, Mathieu Y; Peacock, Ben; Federici, Angelica S; Hoey, David A; Cox, Sophie C.

Int J Mol Sci ; 23(2)2022 Jan 13.

Article in English | MEDLINE | ID: mdl-35055017

14.

The importance of increasing population diversity in genetic studies of type 2 diabetes and related glycaemic traits.

Barroso, Inês.

Diabetologia ; 64(12): 2653-2664, 2021 12.

Article in English | MEDLINE | ID: mdl-34595549

15.

DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency.

Logan, Clare V; Murray, Jennie E; Parry, David A; Robertson, Andrea; Bellelli, Roberto; Tarnauskaite, Zygimante; Challis, Rachel; Cleal, Louise; Borel, Valerie; Fluteau, Adeline; Santoyo-Lopez, Javier; Aitman, Tim; Barroso, Inês; Basel, Donald; Bicknell, Louise S; Goel, Himanshu; Hu, Hao; Huff, Chad; Hutchison, Michele; Joyce, Caroline; Knox, Rachel; Lacroix, Amy E; Langlois, Sylvie; McCandless, Shawn; McCarrier, Julie; Metcalfe, Kay A; Morrissey, Rose; Murphy, Nuala; Netchine, Irène; O'Connell, Susan M; Olney, Ann Haskins; Paria, Nandina; Rosenfeld, Jill A; Sherlock, Mark; Syverson, Erin; White, Perrin C; Wise, Carol; Yu, Yao; Zacharin, Margaret; Banerjee, Indraneel; Reijns, Martin; Bober, Michael B; Semple, Robert K; Boulton, Simon J; Rios, Jonathan J; Jackson, Andrew P.

Am J Hum Genet ; 103(6): 1038-1044, 2018 12 06.

Article in English | MEDLINE | ID: mdl-30503519

16.

The UK10K project identifies rare variants in health and disease.

Walter, Klaudia; Min, Josine L; Huang, Jie; Crooks, Lucy; Memari, Yasin; McCarthy, Shane; Perry, John R B; Xu, ChangJiang; Futema, Marta; Lawson, Daniel; Iotchkova, Valentina; Schiffels, Stephan; Hendricks, Audrey E; Danecek, Petr; Li, Rui; Floyd, James; Wain, Louise V; Barroso, Inês; Humphries, Steve E; Hurles, Matthew E; Zeggini, Eleftheria; Barrett, Jeffrey C; Plagnol, Vincent; Richards, J Brent; Greenwood, Celia M T; Timpson, Nicholas J; Durbin, Richard; Soranzo, Nicole.

Nature ; 526(7571): 82-90, 2015 Oct 01.

Article in English | MEDLINE | ID: mdl-26367797

17.

ProxECAT: Proxy External Controls Association Test. A new case-control gene region association test using allele frequencies from public controls.

Hendricks, Audrey E; Billups, Stephen C; Pike, Hamish N C; Farooqi, I Sadaf; Zeggini, Eleftheria; Santorico, Stephanie A; Barroso, Inês; Dupuis, Josée.

PLoS Genet ; 14(10): e1007591, 2018 10.

Article in English | MEDLINE | ID: mdl-30325923

18.

Bullying investigations need a code of conduct.

Nik-Zainal, Serena; Barroso, Inês.

Nature ; 565(7740): 429, 2019 01.

Article in English | MEDLINE | ID: mdl-30675047

19.

Genome-wide association study of type 2 diabetes in Africa.

Chen, Ji; Sun, Meng; Adeyemo, Adebowale; Pirie, Fraser; Carstensen, Tommy; Pomilla, Cristina; Doumatey, Ayo P; Chen, Guanjie; Young, Elizabeth H; Sandhu, Manjinder; Morris, Andrew P; Barroso, Inês; McCarthy, Mark I; Mahajan, Anubha; Wheeler, Eleanor; Rotimi, Charles N; Motala, Ayesha A.

Diabetologia ; 62(7): 1204-1211, 2019 07.

Article in English | MEDLINE | ID: mdl-31049640

20.

Genetic aetiology of glycaemic traits: approaches and insights.

Wheeler, Eleanor; Marenne, Gaëlle; Barroso, Inês.

Hum Mol Genet ; 26(R2): R172-R184, 2017 10 01.

Article in English | MEDLINE | ID: mdl-28977447

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