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1.

VEGF in Signaling and Disease: Beyond Discovery and Development.

Apte, Rajendra S; Chen, Daniel S; Ferrara, Napoleone.

Cell ; 176(6): 1248-1264, 2019 03 07.

Article in English | MEDLINE | ID: mdl-30849371

2.

Immunity as biophysics at the surface of a T cell.

Chen, Daniel S.

Immunity ; 57(2): 193-195, 2024 Feb 13.

Article in English | MEDLINE | ID: mdl-38354696

3.

The cancer-immunity cycle: Indication, genotype, and immunotype.

Mellman, Ira; Chen, Daniel S; Powles, Thomas; Turley, Shannon J.

Immunity ; 56(10): 2188-2205, 2023 10 10.

Article in English | MEDLINE | ID: mdl-37820582

4.

Top 10 Challenges in Cancer Immunotherapy.

Hegde, Priti S; Chen, Daniel S.

Immunity ; 52(1): 17-35, 2020 01 14.

Article in English | MEDLINE | ID: mdl-31940268

5.

TGFß attenuates tumour response to PD-L1 blockade by contributing to exclusion of T cells.

Mariathasan, Sanjeev; Turley, Shannon J; Nickles, Dorothee; Castiglioni, Alessandra; Yuen, Kobe; Wang, Yulei; Kadel, Edward E; Koeppen, Hartmut; Astarita, Jillian L; Cubas, Rafael; Jhunjhunwala, Suchit; Banchereau, Romain; Yang, Yagai; Guan, Yinghui; Chalouni, Cecile; Ziai, James; Senbabaoglu, Yasin; Santoro, Stephen; Sheinson, Daniel; Hung, Jeffrey; Giltnane, Jennifer M; Pierce, Andrew A; Mesh, Kathryn; Lianoglou, Steve; Riegler, Johannes; Carano, Richard A D; Eriksson, Pontus; Höglund, Mattias; Somarriba, Loan; Halligan, Daniel L; van der Heijden, Michiel S; Loriot, Yohann; Rosenberg, Jonathan E; Fong, Lawrence; Mellman, Ira; Chen, Daniel S; Green, Marjorie; Derleth, Christina; Fine, Gregg D; Hegde, Priti S; Bourgon, Richard; Powles, Thomas.

Nature ; 554(7693): 544-548, 2018 02 22.

Article in English | MEDLINE | ID: mdl-29443960

6.

Elements of cancer immunity and the cancer-immune set point.

Chen, Daniel S; Mellman, Ira.

Nature ; 541(7637): 321-330, 2017 01 18.

Article in English | MEDLINE | ID: mdl-28102259

7.

Oncology meets immunology: the cancer-immunity cycle.

Chen, Daniel S; Mellman, Ira.

Immunity ; 39(1): 1-10, 2013 Jul 25.

Article in English | MEDLINE | ID: mdl-23890059

8.

Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti-PD-L1).

Kowanetz, Marcin; Zou, Wei; Gettinger, Scott N; Koeppen, Hartmut; Kockx, Mark; Schmid, Peter; Kadel, Edward E; Wistuba, Ignacio; Chaft, Jamie; Rizvi, Naiyer A; Spigel, David R; Spira, Alexander; Hirsch, Fred R; Cohen, Victor; Smith, Dustin; Boyd, Zach; Miley, Natasha; Flynn, Susan; Leveque, Vincent; Shames, David S; Ballinger, Marcus; Mocci, Simonetta; Shankar, Geetha; Funke, Roel; Hampton, Garret; Sandler, Alan; Amler, Lukas; Mellman, Ira; Chen, Daniel S; Hegde, Priti S.

Proc Natl Acad Sci U S A ; 115(43): E10119-E10126, 2018 10 23.

Article in English | MEDLINE | ID: mdl-30297397

9.

MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer.

Powles, Thomas; Eder, Joseph Paul; Fine, Gregg D; Braiteh, Fadi S; Loriot, Yohann; Cruz, Cristina; Bellmunt, Joaquim; Burris, Howard A; Petrylak, Daniel P; Teng, Siew-leng; Shen, Xiaodong; Boyd, Zachary; Hegde, Priti S; Chen, Daniel S; Vogelzang, Nicholas J.

Nature ; 515(7528): 558-62, 2014 Nov 27.

Article in English | MEDLINE | ID: mdl-25428503

10.

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients.

Herbst, Roy S; Soria, Jean-Charles; Kowanetz, Marcin; Fine, Gregg D; Hamid, Omid; Gordon, Michael S; Sosman, Jeffery A; McDermott, David F; Powderly, John D; Gettinger, Scott N; Kohrt, Holbrook E K; Horn, Leora; Lawrence, Donald P; Rost, Sandra; Leabman, Maya; Xiao, Yuanyuan; Mokatrin, Ahmad; Koeppen, Hartmut; Hegde, Priti S; Mellman, Ira; Chen, Daniel S; Hodi, F Stephen.

Nature ; 515(7528): 563-7, 2014 Nov 27.

Article in English | MEDLINE | ID: mdl-25428504

11.

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial.

Rittmeyer, Achim; Barlesi, Fabrice; Waterkamp, Daniel; Park, Keunchil; Ciardiello, Fortunato; von Pawel, Joachim; Gadgeel, Shirish M; Hida, Toyoaki; Kowalski, Dariusz M; Dols, Manuel Cobo; Cortinovis, Diego L; Leach, Joseph; Polikoff, Jonathan; Barrios, Carlos; Kabbinavar, Fairooz; Frontera, Osvaldo Arén; De Marinis, Filippo; Turna, Hande; Lee, Jong-Seok; Ballinger, Marcus; Kowanetz, Marcin; He, Pei; Chen, Daniel S; Sandler, Alan; Gandara, David R.

Lancet ; 389(10066): 255-265, 2017 01 21.

Article in English | MEDLINE | ID: mdl-27979383

12.

Atezolizumab versus docetaxel for patients with previously treated non-small-cell lung cancer (POPLAR): a multicentre, open-label, phase 2 randomised controlled trial.

Fehrenbacher, Louis; Spira, Alexander; Ballinger, Marcus; Kowanetz, Marcin; Vansteenkiste, Johan; Mazieres, Julien; Park, Keunchil; Smith, David; Artal-Cortes, Angel; Lewanski, Conrad; Braiteh, Fadi; Waterkamp, Daniel; He, Pei; Zou, Wei; Chen, Daniel S; Yi, Jing; Sandler, Alan; Rittmeyer, Achim.

Lancet ; 387(10030): 1837-46, 2016 Apr 30.

Article in English | MEDLINE | ID: mdl-26970723

13.

Maximizing the value of phase III trials in immuno-oncology: A checklist from the Society for Immunotherapy of Cancer (SITC).

Atkins, Michael B; Abu-Sbeih, Hamzah; Ascierto, Paolo A; Bishop, Michael R; Chen, Daniel S; Dhodapkar, Madhav; Emens, Leisha A; Ernstoff, Marc S; Ferris, Robert L; Greten, Tim F; Gulley, James L; Herbst, Roy S; Humphrey, Rachel W; Larkin, James; Margolin, Kim A; Mazzarella, Luca; Ramalingam, Suresh S; Regan, Meredith M; Rini, Brian I; Sznol, Mario.

J Immunother Cancer ; 10(9)2022 09.

Article in English | MEDLINE | ID: mdl-36175037

14.

Abscopal effect in a patient with melanoma.

Hiniker, Susan M; Chen, Daniel S; Knox, Susan J.

N Engl J Med ; 366(21): 2035; author reply 2035-6, 2012 05 24.

Article in English | MEDLINE | ID: mdl-22621637

15.

Dendritic cells dictate responses to PD-L1 blockade cancer immunotherapy.

Mayoux, Maud; Roller, Andreas; Pulko, Vesna; Sammicheli, Stefano; Chen, Stanford; Sum, Eva; Jost, Christian; Fransen, Marieke F; Buser, Regula B; Kowanetz, Marcin; Rommel, Karolin; Matos, Ines; Colombetti, Sara; Belousov, Anton; Karanikas, Vaios; Ossendorp, Ferry; Hegde, Priti S; Chen, Daniel S; Umana, Pablo; Perro, Mario; Klein, Christian; Xu, Wei.

Sci Transl Med ; 12(534)2020 03 11.

Article in English | MEDLINE | ID: mdl-32161104

16.

Safety, Clinical Activity, and Biological Correlates of Response in Patients with Metastatic Melanoma: Results from a Phase I Trial of Atezolizumab.

Hamid, Omid; Molinero, Luciana; Bolen, Christopher R; Sosman, Jeffrey A; Muñoz-Couselo, Eva; Kluger, Harriet M; McDermott, David F; Powderly, John D; Sarkar, Indrani; Ballinger, Marcus; Fassò, Marcella; O'Hear, Carol; Chen, Daniel S; Hegde, Priti S; Hodi, F Stephen.

Clin Cancer Res ; 25(20): 6061-6072, 2019 10 15.

Article in English | MEDLINE | ID: mdl-31358540

17.

Combinations of Bevacizumab With Cancer Immunotherapy.

Chen, Daniel S; Hurwitz, Herbert.

Cancer J ; 24(4): 193-204, 2018.

Article in English | MEDLINE | ID: mdl-30119083

18.

Immune-Modified Response Evaluation Criteria In Solid Tumors (imRECIST): Refining Guidelines to Assess the Clinical Benefit of Cancer Immunotherapy.

Hodi, F Stephen; Ballinger, Marcus; Lyons, Benjamin; Soria, Jean-Charles; Nishino, Mizuki; Tabernero, Josep; Powles, Thomas; Smith, David; Hoos, Axel; McKenna, Chris; Beyer, Ulrich; Rhee, Ina; Fine, Gregg; Winslow, Nathan; Chen, Daniel S; Wolchok, Jedd D.

J Clin Oncol ; 36(9): 850-858, 2018 03 20.

Article in English | MEDLINE | ID: mdl-29341833

19.

Publisher Correction: Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott, David F; Huseni, Mahrukh A; Atkins, Michael B; Motzer, Robert J; Rini, Brian I; Escudier, Bernard; Fong, Lawrence; Joseph, Richard W; Pal, Sumanta K; Reeves, James A; Sznol, Mario; Hainsworth, John; Rathmell, W Kimryn; Stadler, Walter M; Hutson, Thomas; Gore, Martin E; Ravaud, Alain; Bracarda, Sergio; Suárez, Cristina; Danielli, Riccardo; Gruenwald, Viktor; Choueiri, Toni K; Nickles, Dorothee; Jhunjhunwala, Suchit; Piault-Louis, Elisabeth; Thobhani, Alpa; Qiu, Jiaheng; Chen, Daniel S; Hegde, Priti S; Schiff, Christina; Fine, Gregg D; Powles, Thomas.

Nat Med ; 24(12): 1941, 2018 Dec.

Article in English | MEDLINE | ID: mdl-30291359

20.

Clinical activity and molecular correlates of response to atezolizumab alone or in combination with bevacizumab versus sunitinib in renal cell carcinoma.

McDermott, David F; Huseni, Mahrukh A; Atkins, Michael B; Motzer, Robert J; Rini, Brian I; Escudier, Bernard; Fong, Lawrence; Joseph, Richard W; Pal, Sumanta K; Reeves, James A; Sznol, Mario; Hainsworth, John; Rathmell, W Kimryn; Stadler, Walter M; Hutson, Thomas; Gore, Martin E; Ravaud, Alain; Bracarda, Sergio; Suárez, Cristina; Danielli, Riccardo; Gruenwald, Viktor; Choueiri, Toni K; Nickles, Dorothee; Jhunjhunwala, Suchit; Piault-Louis, Elisabeth; Thobhani, Alpa; Qiu, Jiaheng; Chen, Daniel S; Hegde, Priti S; Schiff, Christina; Fine, Gregg D; Powles, Thomas.

Nat Med ; 24(6): 749-757, 2018 06.

Article in English | MEDLINE | ID: mdl-29867230

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