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1.

Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity.

Clayton, Gina M; Wang, Yang; Crawford, Frances; Novikov, Andrey; Wimberly, Brian T; Kieft, Jeffrey S; Falta, Michael T; Bowerman, Natalie A; Marrack, Philippa; Fontenot, Andrew P; Dai, Shaodong; Kappler, John W.

Cell ; 158(1): 132-42, 2014 Jul 03.

Article in English | MEDLINE | ID: mdl-24995984

2.

Aire mediates tolerance to insulin through thymic trimming of high-affinity T cell clones.

Smith, Jennifer A; Yuen, Benjamin T K; Purtha, Whitney; Balolong, Jared M; Phipps, Jonah D; Crawford, Frances; Bluestone, Jeffrey A; Kappler, John W; Anderson, Mark S.

Proc Natl Acad Sci U S A ; 121(20): e2320268121, 2024 May 14.

Article in English | MEDLINE | ID: mdl-38709934

3.

Antiviral CD8⁺ T Cells Restricted by Human Leukocyte Antigen Class II Exist during Natural HIV Infection and Exhibit Clonal Expansion.

Ranasinghe, Srinika; Lamothe, Pedro A; Soghoian, Damien Z; Kazer, Samuel W; Cole, Michael B; Shalek, Alex K; Yosef, Nir; Jones, R Brad; Donaghey, Faith; Nwonu, Chioma; Jani, Priya; Clayton, Gina M; Crawford, Frances; White, Janice; Montoya, Alana; Power, Karen; Allen, Todd M; Streeck, Hendrik; Kaufmann, Daniel E; Picker, Louis J; Kappler, John W; Walker, Bruce D.

Immunity ; 45(4): 917-930, 2016 10 18.

Article in English | MEDLINE | ID: mdl-27760342

4.

Chromogranin A is an autoantigen in type 1 diabetes.

Stadinski, Brian D; Delong, Thomas; Reisdorph, Nichole; Reisdorph, Richard; Powell, Roger L; Armstrong, Michael; Piganelli, Jon D; Barbour, Gene; Bradley, Brenda; Crawford, Frances; Marrack, Philippa; Mahata, Sushil K; Kappler, John W; Haskins, Kathryn.

Nat Immunol ; 11(3): 225-31, 2010 Mar.

Article in English | MEDLINE | ID: mdl-20139986

5.

Intravenous Haloperidol Versus Ondansetron for Cannabis Hyperemesis Syndrome (HaVOC): A Randomized, Controlled Trial.

Ruberto, Aaron J; Sivilotti, Marco L A; Forrester, Savannah; Hall, Andrew K; Crawford, Frances M; Day, Andrew G.

Ann Emerg Med ; 77(6): 613-619, 2021 06.

Article in English | MEDLINE | ID: mdl-33160719

6.

C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes.

Wang, Yang; Sosinowski, Tomasz; Novikov, Andrey; Crawford, Frances; Neau, David B; Yang, Junbao; Kwok, William W; Marrack, Philippa; Kappler, John W; Dai, Shaodong.

Proc Natl Acad Sci U S A ; 115(1): 162-167, 2018 01 02.

Article in English | MEDLINE | ID: mdl-29255035

7.

Evolutionarily conserved features contribute to αß T cell receptor specificity.

Scott-Browne, James P; Crawford, Frances; Young, Mary H; Kappler, John W; Marrack, Philippa; Gapin, Laurent.

Immunity ; 35(4): 526-35, 2011 Oct 28.

Article in English | MEDLINE | ID: mdl-21962492

8.

A single T cell receptor bound to major histocompatibility complex class I and class II glycoproteins reveals switchable TCR conformers.

Yin, Lei; Huseby, Eric; Scott-Browne, James; Rubtsova, Kira; Pinilla, Clamencia; Crawford, Frances; Marrack, Philippa; Dai, Shaodong; Kappler, John W.

Immunity ; 35(1): 23-33, 2011 Jul 22.

Article in English | MEDLINE | ID: mdl-21683626

9.

Modulation of the Alternative Pathway of Complement by Murine Factor H-Related Proteins.

Antonioli, Alexandra H; White, Janice; Crawford, Frances; Renner, Brandon; Marchbank, Kevin J; Hannan, Jonathan P; Thurman, Joshua M; Marrack, Philippa; Holers, V Michael.

J Immunol ; 200(1): 316-326, 2018 01 01.

Article in English | MEDLINE | ID: mdl-29187587

10.

N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes.

Jin, Niyun; Wang, Yang; Crawford, Frances; White, Janice; Marrack, Philippa; Dai, Shaodong; Kappler, John W.

Proc Natl Acad Sci U S A ; 112(43): 13318-23, 2015 Oct 27.

Article in English | MEDLINE | ID: mdl-26453556

11.

Crossreactive T Cells spotlight the germline rules for alphabeta T cell-receptor interactions with MHC molecules.

Dai, Shaodong; Huseby, Eric S; Rubtsova, Kira; Scott-Browne, James; Crawford, Frances; Macdonald, Whitney A; Marrack, Philippa; Kappler, John W.

Immunity ; 28(3): 324-34, 2008 Mar.

Article in English | MEDLINE | ID: mdl-18308592

12.

Tolerance induction in memory CD4 T cells requires two rounds of antigen-specific activation.

David, Alexandria; Crawford, Frances; Garside, Paul; Kappler, John W; Marrack, Philippa; MacLeod, Megan.

Proc Natl Acad Sci U S A ; 111(21): 7735-40, 2014 May 27.

Article in English | MEDLINE | ID: mdl-24821788

13.

Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.

Zhang, Li; Crawford, Frances; Yu, Liping; Michels, Aaron; Nakayama, Maki; Davidson, Howard W; Kappler, John W; Eisenbarth, George S.

Proc Natl Acad Sci U S A ; 111(7): 2656-61, 2014 Feb 18.

Article in English | MEDLINE | ID: mdl-24550292

14.

Regulatory T cells modulate granulomatous inflammation in an HLA-DP2 transgenic murine model of beryllium-induced disease.

Mack, Douglas G; Falta, Michael T; McKee, Amy S; Martin, Allison K; Simonian, Philip L; Crawford, Frances; Gordon, Terry; Mercer, Robert R; Hoover, Mark D; Marrack, Philippa; Kappler, John W; Tuder, Rubin M; Fontenot, Andrew P.

Proc Natl Acad Sci U S A ; 111(23): 8553-8, 2014 Jun 10.

Article in English | MEDLINE | ID: mdl-24912188

15.

Ruberto, Aaron J; Sivilotti, Marco L A; Hall, Andrew K; Crawford, Frances M.

Ann Emerg Med ; 77(5): 555-556, 2021 05.

Article in English | MEDLINE | ID: mdl-33902835

16.

Identification of multiple public TCR repertoires in chronic beryllium disease.

Bowerman, Natalie A; Falta, Michael T; Mack, Douglas G; Wehrmann, Fabian; Crawford, Frances; Mroz, Margaret M; Maier, Lisa A; Kappler, John W; Fontenot, Andrew P.

J Immunol ; 192(10): 4571-80, 2014 May 15.

Article in English | MEDLINE | ID: mdl-24719461

17.

T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy.

Yin, Lei; Crawford, Frances; Marrack, Philippa; Kappler, John W; Dai, Shaodong.

Proc Natl Acad Sci U S A ; 109(45): 18517-22, 2012 Nov 06.

Article in English | MEDLINE | ID: mdl-23091041

18.

Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.

Crawford, Frances; Stadinski, Brian; Jin, Niyun; Michels, Aaron; Nakayama, Maki; Pratt, Philip; Marrack, Philippa; Eisenbarth, George; Kappler, John W.

Proc Natl Acad Sci U S A ; 108(40): 16729-34, 2011 Oct 04.

Article in English | MEDLINE | ID: mdl-21949373

19.

Memory CD4 T cells that express CXCR5 provide accelerated help to B cells.

MacLeod, Megan K L; David, Alexandria; McKee, Amy S; Crawford, Frances; Kappler, John W; Marrack, Philippa.

J Immunol ; 186(5): 2889-96, 2011 Mar 01.

Article in English | MEDLINE | ID: mdl-21270407

20.

Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register.

Stadinski, Brian D; Zhang, Li; Crawford, Frances; Marrack, Philippa; Eisenbarth, George S; Kappler, John W.

Proc Natl Acad Sci U S A ; 107(24): 10978-83, 2010 Jun 15.

Article in English | MEDLINE | ID: mdl-20534455

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