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1.

Single-cell, whole-embryo phenotyping of mammalian developmental disorders.

Huang, Xingfan; Henck, Jana; Qiu, Chengxiang; Sreenivasan, Varun K A; Balachandran, Saranya; Amarie, Oana V; Hrabe de Angelis, Martin; Behncke, Rose Yinghan; Chan, Wing-Lee; Despang, Alexandra; Dickel, Diane E; Duran, Madeleine; Feuchtinger, Annette; Fuchs, Helmut; Gailus-Durner, Valerie; Haag, Natja; Hägerling, Rene; Hansmeier, Nils; Hennig, Friederike; Marshall, Cooper; Rajderkar, Sudha; Ringel, Alessa; Robson, Michael; Saunders, Lauren M; da Silva-Buttkus, Patricia; Spielmann, Nadine; Srivatsan, Sanjay R; Ulferts, Sascha; Wittler, Lars; Zhu, Yiwen; Kalscheuer, Vera M; Ibrahim, Daniel M; Kurth, Ingo; Kornak, Uwe; Visel, Axel; Pennacchio, Len A; Beier, David R; Trapnell, Cole; Cao, Junyue; Shendure, Jay; Spielmann, Malte.

Nature ; 623(7988): 772-781, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37968388

2.

Designer enhancers for cell-type-specific gene regulation.

Despang, Alexandra.

Nat Biotechnol ; 42(1): 31, 2024 Jan.

Article in English | MEDLINE | ID: mdl-38233653

3.

Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture.

Despang, Alexandra; Schöpflin, Robert; Franke, Martin; Ali, Salaheddine; Jerkovic, Ivana; Paliou, Christina; Chan, Wing-Lee; Timmermann, Bernd; Wittler, Lars; Vingron, Martin; Mundlos, Stefan; Ibrahim, Daniel M.

Nat Genet ; 51(8): 1263-1271, 2019 08.

Article in English | MEDLINE | ID: mdl-31358994

4.

Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.

Kraft, Katerina; Magg, Andreas; Heinrich, Verena; Riemenschneider, Christina; Schöpflin, Robert; Markowski, Julia; Ibrahim, Daniel M; Acuna-Hidalgo, Rocío; Despang, Alexandra; Andrey, Guillaume; Wittler, Lars; Timmermann, Bernd; Vingron, Martin; Mundlos, Stefan.

Nat Cell Biol ; 21(3): 305-310, 2019 03.

Article in English | MEDLINE | ID: mdl-30742094

5.

Linking genetic variants to cellular function and disease.

Despang, Alexandra.

Nat Biotechnol ; 41(1): 21, 2023 01.

Article in English | MEDLINE | ID: mdl-36653495

6.

Gene therapy for walking recovery after paralysis.

Despang, Alexandra.

Nat Biotechnol ; 41(11): 1521, 2023 Nov.

Article in English | MEDLINE | ID: mdl-37950011

7.

Monitoring protein proximity with fluorogens.

Despang, Alexandra.

Nat Biotechnol ; 41(10): 1386, 2023 Oct.

Article in English | MEDLINE | ID: mdl-37828286

8.

Spatial transcriptomics with light barcodes in intact tissues.

Despang, Alexandra.

Nat Biotechnol ; 40(11): 1575, 2022 11.

Article in English | MEDLINE | ID: mdl-36347989

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Single-cell, whole-embryo phenotyping of mammalian developmental disorders.

Designer enhancers for cell-type-specific gene regulation.

Functional dissection of the Sox9-Kcnj2 locus identifies nonessential and instructive roles of TAD architecture.

Serial genomic inversions induce tissue-specific architectural stripes, gene misexpression and congenital malformations.

Linking genetic variants to cellular function and disease.

Gene therapy for walking recovery after paralysis.

Monitoring protein proximity with fluorogens.

Spatial transcriptomics with light barcodes in intact tissues.