ABSTRACT
According to the literature, serrated lesions and polyps of the appendix are extremely rare in children or teenagers. Herein, we present the pathologic and molecular features of a sessile serrated lesion (SSL) that was incidentally found in the appendix of a teenage girl. Our findings not only illustrate that appendiceal SSL may occur in young patients such as teenagers but also confirm further that BRAF V600E mutation may be found in a subset of these neoplastic lesions.
Subject(s)
Appendix/pathology , Cecal Diseases/pathology , Proto-Oncogene Proteins B-raf/genetics , Adolescent , Cecal Diseases/diagnosis , Cecal Diseases/genetics , Female , Genetic Markers , Humans , Incidental Findings , Point MutationSubject(s)
Anal Canal , Condylomata Acuminata/diagnosis , Syphilis, Cutaneous/diagnosis , Syphilis/diagnosis , Treponema pallidum/isolation & purification , Adult , Anal Canal/microbiology , Anal Canal/pathology , Anal Canal/surgery , Diagnosis, Differential , Humans , Male , Predictive Value of Tests , Syphilis/microbiology , Syphilis/pathology , Syphilis/surgery , Syphilis, Cutaneous/microbiology , Syphilis, Cutaneous/pathology , Syphilis, Cutaneous/surgerySubject(s)
Abdominal Pain/etiology , Dendritic Cell Sarcoma, Follicular/complications , Epstein-Barr Virus Infections/complications , Granuloma, Plasma Cell/complications , Aged , Dendritic Cell Sarcoma, Follicular/diagnostic imaging , Dendritic Cell Sarcoma, Follicular/pathology , Epstein-Barr Virus Infections/diagnosis , Female , Granuloma, Plasma Cell/diagnostic imaging , Granuloma, Plasma Cell/pathology , Humans , Tomography, X-Ray ComputedSubject(s)
Cooking and Eating Utensils , Deglutition Disorders/etiology , Esophagus , Foreign Bodies/complications , Adult , Humans , MaleABSTRACT
In patients with portal hypertension, ileostomy or colostomy carries the risk of the development of stomal varices at the site of the mucocutaneous junction of a stoma. Such varices are often the source of difficult-to-treat recurrent or chronic bleeding. In this setting, transjugular intrahepatic portosystemic shunt insertion and embolisation is considered the best therapeutic approach in spite of relatively high mortality and morbidity rates. We report the cases of three consecutive patients with portal hypertension of various causes and chronic stomal variceal bleeding in whom beta-blocking therapy resulted in the drying up of bleeding and the prevention of its recurrence for periods of time ranging between 2 and 42 months.
Subject(s)
Adrenergic beta-Antagonists/therapeutic use , Colostomy/adverse effects , Gastrointestinal Hemorrhage/drug therapy , Hypertension, Portal/complications , Varicose Veins/drug therapy , Aged , Chronic Disease , Gastrointestinal Hemorrhage/etiology , Humans , Male , Middle Aged , Propranolol/therapeutic use , Surgical Stomas/blood supply , Varicose Veins/complicationsABSTRACT
We report a case of late perforation of the thoracic esophagus with an esophagopleural fistula after endoscopic sclerotherapy for esophageal varices in a Child-Pugh B9 cirrhotic patient. The existence of a thoracic empyema without diffuse mediastinitis allowed management of the fistula by percutaneous drainage-lavage and antibiotic therapy with subsequent closure of the esophageal wall defect and recovery from sepsis. This observation indicates that minimally invasive management of an esophageal perforation complicated by an esophago-pleural fistula is possible in highly selected patients.