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Vestn Otorinolaringol ; 88(6): 91-96, 2023.
Article in Russian | MEDLINE | ID: mdl-38153899

ABSTRACT

Tumor induced osteomalacia is a rare paraneoplastic syndrome caused by mesenchymal tumors that secrete fibroblast growth factor 23 (FGF23). Patients complain of progressive bone pain, muscle weakness and brittle fractures. Delayed diagnosis of osteomalacia caused by a tumor is often found in clinical practice. When verifying the exact localization of the neoplasm, radical removal within healthy tissues is recommended. The article considers a clinical example of FGF23 tumor induced osteomalacia with localization of neoplasm in the tympanic cavity.


Subject(s)
Neoplasms, Connective Tissue , Osteomalacia , Paraneoplastic Syndromes , Humans , Ear, Middle/pathology , Neoplasms, Connective Tissue/diagnosis , Neoplasms, Connective Tissue/etiology , Neoplasms, Connective Tissue/surgery , Osteomalacia/diagnosis , Osteomalacia/etiology , Paraneoplastic Syndromes/etiology , Paraneoplastic Syndromes/complications
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