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1.
Med Humanit ; 50(3): 494-503, 2024 Sep 23.
Article in English | MEDLINE | ID: mdl-38548326

ABSTRACT

The emergence of new body technologies has led to the deconstruction of a cosmetically enhanced celebrity body into a bioinformational data-self, which becomes a surveilled subject quantified through biometric proximity. Evidently, the bodies of Indian Hindi film actresses evolve into material sites for the discursive encoding, bioinformational performativity and transference of disciplining hegemonic beauty ideals. In this age of information, the celebrity capital and postdigital positionality of celebrity bodies grant their bioinformational spectacular performance with a potential biologising affect for the further corporealisation of popular body aesthetics. Drawing on the maxims of new materialisms and neoliberal subjectivities, the article seeks to decipher the entanglement between the cultural economy of Indian Hindi film stars, their enhanced biometric dynamics and biologising spectacular performativity. Indian Hindi film industry, media, tabloids, magazines, celebrity culture and aesthetic clinics situate Indian Hindi film actresses under vigilant surveillance and simulcast their cosmetic consumption and technologically enhanced bodies across the visual-online attention economy. The present study, therefore exposes the enhanced bodies and biometric dynamics of Indian Hindi film actresses as the human and non-human agentic forms of industrialised cosmetic culture and neoliberal bioconsumerism.


Subject(s)
Beauty , Motion Pictures , Surgery, Plastic , Humans , India , Female , Biometry , Esthetics , Culture , Hinduism
2.
BMC Cardiovasc Disord ; 17(1): 191, 2017 07 17.
Article in English | MEDLINE | ID: mdl-28716059

ABSTRACT

BACKGROUND: We aimed to systematically compare Major Adverse Cardiac Events (MACEs) and mortality following Percutaneous Coronary Intervention (PCI) in patients with and without Chronic Obstructive Pulmonary Diseases (COPD) through a meta-analysis. METHODS: Electronic databases (Cochrane library, EMBASE and Medline/PubMed) were searched for English publications comparing in-hospital and long-term MACEs and mortality following PCI in patients with a past medical history of COPD. Statistical analysis was carried out by Revman 5.3 whereby Odds Ratio (OR) and 95% Confidence Intervals (CI) were considered the relevant parameters. RESULTS: A total number of 72,969 patients were included (7518 patients with COPD and 65,451 patients without COPD). Results of this analysis showed that in-hospital MACEs were significantly higher in the COPD group with OR: 1.40, 95% CI: 1.19-1.65; P = 0.0001, I2 = 0%. Long-term MACEs were still significantly higher in the COPD group with OR: 1.58, 95% CI: 1.38-1.81; P = 0.00001, I2 = 29%. Similarly, in-hospital and long-term mortality were significantly higher in patients with COPD, with OR: 2.25, 95% CI: 1.78-2.85; P = 0.00001, I2 = 0% and OR: 2.22, 95% CI: 1.33-3.71; P = 0.002, I2 = 97% respectively. However, the result for the long-term death was highly heterogeneous. CONCLUSION: Since in-hospital and long-term MACEs and mortality were significantly higher following PCI in patients with versus without COPD, COPD should be considered a risk factor for the development of adverse clinical outcomes following PCI. However, the result for the long-term mortality was highly heterogeneous warranting further analysis.


Subject(s)
Heart Diseases/therapy , Percutaneous Coronary Intervention/mortality , Pulmonary Disease, Chronic Obstructive/mortality , Chi-Square Distribution , Heart Diseases/complications , Heart Diseases/diagnosis , Heart Diseases/mortality , Hospital Mortality , Humans , Odds Ratio , Percutaneous Coronary Intervention/adverse effects , Pulmonary Disease, Chronic Obstructive/complications , Pulmonary Disease, Chronic Obstructive/diagnosis , Risk Assessment , Risk Factors , Time Factors , Treatment Outcome
3.
South Med J ; 101(5): 556-7, 2008 May.
Article in English | MEDLINE | ID: mdl-18414160

ABSTRACT

A 64-year-old female patient presented with acute cerebellar ataxia. After ruling out vascular, infectious, metastatic, demyelinating, and medication etiologies, a paraneoplastic origin for her illness was determined. A renal mass was discovered and found to be renal cell carcinoma. Her symptoms resolved after a radical nephrectomy. Physicians should consider the diagnosis of paraneoplastic neurologic syndromes whenever a thorough evaluation fails to explain neurologic abnormalities.


Subject(s)
Carcinoma, Renal Cell/complications , Cerebellar Ataxia/etiology , Kidney Neoplasms/complications , Paraneoplastic Cerebellar Degeneration/etiology , Carcinoma, Renal Cell/diagnostic imaging , Carcinoma, Renal Cell/immunology , Female , Humans , Kidney Neoplasms/diagnostic imaging , Kidney Neoplasms/immunology , Middle Aged , Paraneoplastic Cerebellar Degeneration/immunology , Tomography, X-Ray Computed
4.
J Clin Pathol ; 60(4): 428-31, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17405979

ABSTRACT

Angiomyolipoma (AML) is a rare benign neoplasm that usually arises in the kidneys, but may rarely originate in sites such as the retroperitoneum, liver and bone. It is characterised by an intimate admixture of blood vessels, smooth muscle and fat. This multiphasic composition allows for its recognition on ultrasound and CT scan examination. Metastases are exceedingly uncommon, and only one other case of metastatic extrarenal AML exists in the literature. Histological variants of AML such as epithelioid angiomyolipoma (EAML) are considered to be locally aggressive. A unique case of an EAML of the retroperitoneum that metastasised to the liver and bone in an 80-year-old woman is described.


Subject(s)
Angiomyolipoma/pathology , Liver Neoplasms/secondary , Retroperitoneal Neoplasms/pathology , Aged, 80 and over , Angiomyolipoma/diagnosis , Bone Neoplasms/diagnosis , Bone Neoplasms/pathology , Bone Neoplasms/secondary , Female , Humans , Liver Neoplasms/diagnosis , Liver Neoplasms/pathology
5.
Medicine (Baltimore) ; 96(46): e8748, 2017 Nov.
Article in English | MEDLINE | ID: mdl-29145326

ABSTRACT

BACKGROUND: Nowadays, fraction flow reserve (FFR) is being discussed in every percutaneous coronary intervention (PCI) capable hospitals. Owing to recent development in the medical field, FFR-guided PCI should be able to find a place in Interventional Cardiology. At present, the importance of FFR to stratify patients who require PCI has seldom systematically been investigated. In this analysis, we aimed to compare the major adverse cardiac events (MACEs) mainly in patients with stable coronary artery disease (CAD) to whom PCI was recommended and deferred respectively based on the FFR value. METHODS: Electronic databases were searched for studies comparing FFR-recommended versus FFR-deferred coronary stenting. Long-term MACEs, mortality, and myocardial infarction (MI) were considered as the clinical endpoints in this analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated and the analyses were carried out by the latest version of the RevMan software. RESULTS: A total number of 1753 patients (670 patients were revascularized, whereas 1083 patients were deferred from revascularization based on the FFR value) were analyzed. Current results showed MACEs and MI were significantly higher in the FFR-recommended PCI group with OR 1.34 (95% CI: 1.05-1.72; P = .02) and OR 1.73 (95% CI: 1.19-2.51; P = .004, I = 0%), respectively. However, mortality was similarly manifested with OR 1.23 (95% CI: 0.92-1.63; P = .16, I = 0%). CONCLUSION: Significantly higher MACEs were observed in patients to whom PCI was recommended compared to those patients who were deferred from undergoing PCI based on the FFR values. Therefore, FFR might indeed be an important decision-making procedural tool, which should be used to stratify stable CAD patients with an advanced disease and who are qualified candidates for PCI. Further research should confirm this hypothesis.


Subject(s)
Clinical Decision-Making/methods , Coronary Artery Disease/physiopathology , Fractional Flow Reserve, Myocardial/physiology , Patient Selection , Percutaneous Coronary Intervention/methods , Aged , Coronary Artery Disease/mortality , Coronary Artery Disease/surgery , Female , Humans , Male , Middle Aged , Myocardial Infarction/etiology , Myocardial Infarction/mortality , Odds Ratio , Percutaneous Coronary Intervention/mortality , Postoperative Complications/etiology , Postoperative Complications/mortality , Risk Factors , Stents , Treatment Outcome
6.
Clin Lymphoma Myeloma ; 6(4): 333-6, 2006 Jan.
Article in English | MEDLINE | ID: mdl-16507212

ABSTRACT

Adult Burkitt's lymphoma is an uncommon disease. Few cases of spinal involvement in adults with sporadic Burkitt's lymphoma are reported in the literature. We present a case of a middle-aged man who was found to have an epidural mass in the thoracic spine when investigated for back pain and lower extremity weakness. He underwent a laminectomy with resection of the epidural mass. Histologic examination revealed a primary Burkitt's lymphoma of the spinal cord. He was treated with aggressive chemotherapy and is now experiencing remission of his disease. We also present a review of the literature for the etiology and clinical features of other spinal lymphomas and Burkitt's lymphoma involving the spine in adults.


Subject(s)
Burkitt Lymphoma/pathology , Epidural Neoplasms/pathology , Burkitt Lymphoma/therapy , Epidural Neoplasms/secondary , Epidural Neoplasms/therapy , Humans , Laminectomy/methods , Male , Middle Aged , Remission Induction/methods
7.
Pathol Res Pract ; 202(6): 465-9, 2006.
Article in English | MEDLINE | ID: mdl-16497446

ABSTRACT

Pure and primary squamous cell carcinomas of the breast are exceedingly uncommon lesions. To the best of our knowledge, based up on review of the literature, only four studies of patients with these tumors, which presented clinically as breast abscess, have been reported previously. We present a woman who sought medical attention for breast pain and was initially diagnosed with a breast abscess. When she did not respond to antibiotic therapy, an incision as well as drainage was performed. Histologic examination of the material revealed a pure squamous cell carcinoma. An extensive work up ruled out other primary sites. She was treated with mastectomy and radiation therapy and has seen disease-free 3 years postdiagnosis. We also review the literature for presenting features, value of imaging studies, role of cytology in diagnosis, and therapy of such tumors in comparison to the usual ductal carcinomas of the breast.


Subject(s)
Breast Neoplasms/pathology , Carcinoma, Ductal, Breast/pathology , Carcinoma, Squamous Cell/pathology , Adult , Breast Neoplasms/therapy , Carcinoma, Squamous Cell/therapy , Disease-Free Survival , Female , Humans , Mastectomy , Radiotherapy, Adjuvant
8.
World J Surg Oncol ; 4: 15, 2006 Mar 27.
Article in English | MEDLINE | ID: mdl-16566835

ABSTRACT

BACKGROUND: Metastatic breast carcinoids are rare neoplasms. They can be mistaken for primary breast carcinoma both clinically and radiologically, even with known history of carcinoid tumor elsewhere in the body. CASE PRESENTATION: We report a case of unilateral breast metastasis from carcinoid tumor of the small intestine in a 52-year-old woman who was successfully treated by lumpectomy and radiation therapy. An extensive review of the literature reveals only a few cases of metastatic carcinoid to the breast from small intestinal primaries. CONCLUSION: Clinical suspicion for metastasis should be high in a patient with breast mass and history of known carcinoid elsewhere in the body. Lumpectomy alone may be effective in these patients. Mastectomy and especially axillary dissection could be avoided. Their histological appearance may mimic ductal adenocarcinoma of the breast. However, the distinction is important due to differences in management and prognosis.

9.
J Natl Med Assoc ; 98(6): 977-9, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16775924

ABSTRACT

Nocardia farcinica is an uncommon cause of nocardiosis and usually infects immunocompromised individuals. We describe a patient with Hodgkin's disease and a thigh abscess due to N. farcinica. To the best of our knowledge, this has never been reported before in the English literature. It is important to recognize this complication, because a delay in diagnosis may result in widespread dissemination. Unless initially suspected, culture and identification will be delayed, as selective media for isolating Nocardia are not routinely used in most clinical laboratories. It is also important to differentiate N. farcinica from other Nocardia species due to its resistance to many antibiotics that are routinely used to treat abscesses, including cephalosporins. A case report along with literature review is presented in an effort to stress the importance of including this pathogen in the differential diagnosis of immunocompromised patients with abscesses.


Subject(s)
Abscess/microbiology , Hodgkin Disease/drug therapy , Nocardia Infections/diagnosis , Nocardia/isolation & purification , Thigh/microbiology , Abscess/diagnosis , Aged , Diagnosis, Differential , Female , Hodgkin Disease/complications , Humans , Immunosuppressive Agents/immunology , Immunosuppressive Agents/therapeutic use , Nocardia Infections/microbiology , Thigh/physiopathology
10.
Clin Colorectal Cancer ; 5(4): 287-91, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16356308

ABSTRACT

We present a patient with colon carcinoma metastatic to the thyroid. Review of the literature reveals only a few reports of metastatic colorectal carcinoma to the thyroid. Metastatic tumors of the thyroid are no longer considered rare. Unfortunately, they often remain undetected because only a small minority of patients present with a mass lesion or enlargement of the gland. This is further evidenced by the fact that most reports come from autopsy series. Establishing this diagnosis is important because metastatic deposits in the thyroid can sometimes cause respiratory compromise as well as thyrotoxicosis.


Subject(s)
Adenocarcinoma/diagnostic imaging , Fluorodeoxyglucose F18 , Positron-Emission Tomography , Radiopharmaceuticals , Rectal Neoplasms/pathology , Thyroid Neoplasms/diagnostic imaging , Adenocarcinoma/secondary , Adenocarcinoma/therapy , Antineoplastic Combined Chemotherapy Protocols/therapeutic use , Bone Neoplasms , Camptothecin/analogs & derivatives , Camptothecin/therapeutic use , Colectomy , Female , Fluorouracil/therapeutic use , Humans , Leucovorin/therapeutic use , Liver Neoplasms , Middle Aged , Radiotherapy , Rectal Neoplasms/diagnosis , Rectal Neoplasms/therapy , Thyroid Neoplasms/secondary , Thyroid Neoplasms/therapy , Thyroidectomy , Treatment Outcome
11.
17.
Dig Dis Sci ; 52(2): 555-7, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17219075

ABSTRACT

Pulmonary hypertension and cor pulmonale due to tumor emboli causing pulmonary tumor thrombotic microangiopathy (PTTM) is rare and extremely difficult diagnosis to make prior to death. Pulmonary hypertension due to metastatic tumor emboli should be included in the differential diagnosis of various causes of dyspnea in patients with a history of cancer or more common causes, including infection, thromboembolism, metastasis, adverse effects of drugs, and recurrent effusions. We describe a patient with gallbladder carcinoma who presented with progressive dyspnea and severe pulmonary hypertension. The etiology was tumor emboli and PTTM from gallbladder carcinoma, which remained elusive prior to her death despite appropriate clinical investigations and was established on autopsy. To the best of our knowledge, this is likely the second reported case of PTTM from metastatic gallbladder carcinoma.


Subject(s)
Carcinoma, Signet Ring Cell/pathology , Gallbladder Neoplasms/pathology , Hypertension, Pulmonary/etiology , Lung Neoplasms/complications , Lung/blood supply , Pulmonary Embolism/etiology , Thrombosis/etiology , Dyspnea/etiology , Fatal Outcome , Female , Humans , Lung/pathology , Lung Neoplasms/pathology , Lung Neoplasms/secondary , Microcirculation/pathology , Middle Aged , Pulmonary Embolism/pathology , Thrombosis/pathology
18.
Acta Oncol ; 46(2): 247-9, 2007.
Article in English | MEDLINE | ID: mdl-17453377

ABSTRACT

T-cell large granular lymphocyte leukemia (T-LGL) also known as T-cell chronic lymphocytic leukemia is rare and comprises a small minority of all small lymphocytic leukemias. The concomitant presentation of T-LGL with acute myeloid leukemia (AML) has not been previously reported. We present an elderly gentleman with concomitant T-LGL and AML (non-M3) diagnosed by a combination of morphologic evaluation, immunophenotyping by flow cytometry, and T-cell gene rearrangement studies. The patient was managed with combination AML chemotherapy. He remains alive and well seven months after initial diagnosis. A brief review of literature is also presented.


Subject(s)
Leukemia, Myeloid/diagnosis , Leukemia, Prolymphocytic, T-Cell/diagnosis , Acute Disease , Aged, 80 and over , Antigens, CD/analysis , Flow Cytometry , Humans , Leukemia, Myeloid/complications , Male
19.
Arch Pathol Lab Med ; 129(11): 1398-400, 2005 Nov.
Article in English | MEDLINE | ID: mdl-16253018

ABSTRACT

Familial adenomatous polyposis (FAP) is caused by mutation of the adenomatous polyposis coli (APC) gene and is characterized by multiple colorectal adenomas and tumors of other organs and sites. A 58-year-old woman with FAP syndrome and previous total colectomy presented for routine follow-up examination. Abdominal ultrasound and subsequent endoscopic evaluation revealed ampullary and duodenal polyps, as well as inhomogeneity of the pancreatic head. A pancreaticoduodenectomy confirmed multiple duodenal adenomas. In addition, high-grade pancreatic intraepithelial neoplasia (PanIN-3) was found in the smaller pancreatic ducts. Pancreatic precancerous lesions have only rarely been described in FAP, including 2 pancreatic duct adenomas and 2 intraductal papillary mucinous neoplasms. A review of the world English literature revealed no reports of PanIN-3 in association with FAP. Further studies are required to determine if patients with FAP are at increased risk for pancreatic premalignant lesions.


Subject(s)
Adenomatous Polyposis Coli/pathology , Carcinoma in Situ/pathology , Pancreatic Neoplasms/pathology , Adenomatous Polyposis Coli/surgery , Carcinoma in Situ/diagnostic imaging , Carcinoma in Situ/surgery , Colectomy , Duodenal Neoplasms/pathology , Female , Humans , Middle Aged , Neoplasms, Multiple Primary , Pancreatic Ducts/pathology , Pancreatic Neoplasms/diagnostic imaging , Pancreatic Neoplasms/surgery , Precancerous Conditions , Ultrasonography
20.
J Clin Microbiol ; 42(9): 3975-7, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15364978

ABSTRACT

The Centers for Disease Control and Prevention (CDC) recommend universal screening of all pregnant women between 35 and 37 weeks of gestation for group B streptococci (GBS) by use of a selective broth medium. Recent reports suggest that Granada medium can be used for rapid and direct visual identification of GBS colonies. However, studies comparing the Granada medium method to the selective broth method are few, and while some report comparable sensitivities, others have found significant differences in detection rates between the two methods. This prospective study compared a method using Granada agar to a Todd-Hewitt broth method with subculture to blood agar in order to determine which GBS detection method is more sensitive and less labor-intensive and has a more rapid turnaround time. Detection rates for three sampling techniques (rectovaginal, vaginal only, and cervical only) were also compared. Consecutive specimens for GBS screening received over a 6-month period from 1,635 pregnant women were included. Overall, GBS was detected in 390 (23.8%) women. The Granada medium gave positive results for 348 of these women, and the selective broth gave positive results for 385, indicating sensitivities of 89.2% for the Granada medium and 98.7% for the selective broth. These findings show that the Granada medium method is less sensitive than the selective broth method and should not replace it as the only method for screening pregnant women for GBS. However, the Granada medium method reduced detection time to 1 day and also reduced the use of ancillary tests in approximately 90% of positive cases. Additionally, no significant differences were noted in the detection rates with rectovaginal, vaginal, and cervical specimens.


Subject(s)
Pregnancy Complications, Infectious/microbiology , Streptococcus agalactiae/isolation & purification , Vagina/microbiology , Cervix Uteri/microbiology , Culture Media , Female , Humans , Pregnancy , Sensitivity and Specificity , Specimen Handling/methods , Streptococcus agalactiae/growth & development
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