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1.
HPB (Oxford) ; 26(5): 664-673, 2024 05.
Article in English | MEDLINE | ID: mdl-38368218

ABSTRACT

BACKGROUND: Total pancreatectomy with islet autotransplant (TPIAT) can improve quality of life for individuals with pancreatitis but creates health risks including diabetes, exocrine insufficiency, altered intestinal anatomy and function, and asplenia. METHODS: We studied survival and causes of death for 693 patients who underwent TPIAT between 2001 and 2020, using the National Death Index with medical records to ascertain survival after TPIAT, causes of mortality, and risk factors for death. We used Kaplan Meier curves to examine overall survival, and Cox regression and competing-risks methods to determine pre-TPIAT factors associated with all-cause and cause-specific post-TPIAT mortality. RESULTS: Mean age at TPIAT was 33.6 years (SD = 15.1). Overall survival was 93.1% (95% CI 91.2, 95.1%) 5 years after surgery, 85.2% (95% CI 82.0, 88.6%) at 10 years, and 76.2% (95% CI 70.8, 82.3%) at 15 years. Fifty-three of 89 deaths were possibly related to TPIAT; causes included chronic gastrointestinal complications, malnutrition, diabetes, liver failure, and infection/sepsis. In multivariable models, younger age, longer disease duration, and more recent TPIAT were associated with lower mortality. CONCLUSIONS: For patients undergoing TPIAT to treat painful pancreatitis, careful long-term management of comorbidities introduced by TPIAT may reduce risk for common causes of mortality.


Subject(s)
Cause of Death , Islets of Langerhans Transplantation , Pancreatectomy , Humans , Pancreatectomy/adverse effects , Pancreatectomy/mortality , Female , Male , Islets of Langerhans Transplantation/adverse effects , Adult , Risk Factors , Middle Aged , Transplantation, Autologous , Young Adult , Retrospective Studies , Risk Assessment , Time Factors , Adolescent , Treatment Outcome , Pancreatitis/mortality , Pancreatitis/etiology , Pancreatitis, Chronic/surgery , Pancreatitis, Chronic/mortality
2.
Can Rev Sociol ; 57(1): 7-33, 2020 Feb.
Article in English | MEDLINE | ID: mdl-32065496

ABSTRACT

Over the past decade Canadian sociology has engaged in spirited debates on the sociology of sociological research, but it has barely begun to address its relation to Indigenous theorizing, scholarship, and politics. How does the discipline deal with the settler colonial history and current realities of Indigenous social lives, and where is the place in our field for Indigenous voices and perspectives? Drawing on Coulthard's politics of recognition and Tuck's damage-centered research, we present here the first systematic empirical analysis of the place of Indigeneity in the Canadian Review of Sociology and the Canadian Journal of Sociology. We situate the presence of Indigeneity in Canadian sociology journals in the sociopolitical context of the time, and examine how imperialism, statism, and damage are oriented within the two journals. Most importantly, we challenge the silence in the discipline's intellectual frames and research programs with respect to Indigenous theorizing about the social world.


Au cours de la dernière décennie, la sociologie canadienne s'est engagée dans des débats animés sur la sociologie relative à la recherche en sociologie, mais elle ne fait que commencer à aborder ses relations avec la théorisation, les bourses et la politique touchant les Autochtones. Comment cette discipline traite-t-elle de l'histoire coloniale et des réalités actuelles de la vie sociale des Autochtones, et quelle place fait-on dans notre domaine à leur voix et à leurs perspectives? En tirant parti des politiques de reconnaissance de Coulthard (2014) et de la recherche de Tuck axée sur les préjudices (2009), nous vous présentons ici la première analyse empirique systématique de la place de l'indigénéité dans la Revue canadienne de sociologie et dans les Cahiers canadiens de sociologie. Dans des revues de sociologie, nous situons la présence de l'indigénéité dans le contexte socio-politique de l'époque et examinons comment l'impérialisme, l'étatisme et les préjudices sont orientés dans ces deux publications. Et, par-dessus tout, nous remettons en cause le silence des cadres intellectuels et des programmes de recherche de cette discipline à l'égard de la théorisation autochtone au sujet du domaine social.

3.
Soc Sci Res ; 42(3): 596-610, 2013 May.
Article in English | MEDLINE | ID: mdl-23521983

ABSTRACT

In this study of prison privatization we draw on the insights of a recent body of literature that challenges a widespread belief that prisons help to spur employment growth in local communities. We look to these studies to provide an empirically and theoretically grounded approach to addressing our research question: what are the benefits, if any, to employment growth in states that have privatized some of their prisons, compared to states with only public prisons? Our research makes use of a large, national, and comprehensive dataset. By examining the employment contributions of prisons, as recent research has done, we were able to corroborate the general findings of this research. To study prison privatization we distinguish between states in which privatization has grown rapidly and those states in which privatization has grown slowly (or not at all). Our findings lend support to recent research that finds prisons do not improve job prospects for those communities that host them. We contribute to this literature by demonstrating that new prisons in states in which privatization is surging impede employment growth in the host community. To explain this we highlight the significant reduction in prison staffing - in both private and public prisons - where privatization is growing quickly.

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