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1.
Environ Res ; 203: 111815, 2022 01.
Article in English | MEDLINE | ID: mdl-34352231

ABSTRACT

Due to the development in science field which gives not only benefit but also introducesundesirable pollution to the environment. This pollution is due to poor discharge activities of industrial effluents into the soil and water bodies, surface run off from fields of agricultural lands, dumping of untreated wastes by municipalities, and mining activites, which deteriorates the cardinal virtue of our environment and causes menace to human health and life. Heavy metal(s), a natural constituent on earth's crust and economic important mineral, due to its recalcitrant effects creates heavy metal pollution which affects food chain and also reduces the quality of water. For this, many researchers have performed studies to find efficient methods for wastewater remediation. One of the most promising methods from economic point of view is adsorption, which is simple in design, but leads to use of a wide range of adsorbents and ease of operations. Due to advances in nanotechnology, many nanomaterials were used as adsorbents for wastewater remediation, because of their efficiency. Many researchers have reported that nanoadsorbents are unmitigatedly a fruitful solution to address this world's problem. This review presents a potent view on various classes of nanoadsorbents and their application to wastewater treatment. It provides a bird's eye view of the suitability of different types of nanomaterials for remediation of wastewater and Backspace gives up-to-date information about polymer based and silica-based nanoadsorbents.


Subject(s)
Metals, Heavy , Water Pollutants, Chemical , Water Purification , Adsorption , Humans , Metals, Heavy/analysis , Wastewater/analysis , Water Pollutants, Chemical/analysis
2.
Pak J Pharm Sci ; 33(5(Supplementary)): 2347-2350, 2020 Sep.
Article in English | MEDLINE | ID: mdl-33832910

ABSTRACT

The present study validates the antidiabetic potential of Andrographis echioides leaf extract (AeLE) on high fat diet-fed diabetic C57BL/6J mice. The male C57BL/6J mouse (age 6-8 weeks) were divided into 2 groups (lean control group and diabetic group). The lean control group (6 animals) was fed with standard diet pellets. The diabetic group animals (24 animals) were made diabetic by feeding a high-fat diet for 12 weeks. This group was then further divided into 4 groups of 6 animals each and treated orally (for 28 days) with vehicle (0.5%carboxymethyl cellulose), metformin 100mg/kg body weight and 2 different concentrations of test drug viz., 100mg/kg and 200mg/kg body weight. The results show a significant reduction in blood glucose and other biochemical parameters. After 28 days, the metformin and AeLE (200 mg/kg b.w) treated animals had an average serum glucose value of 129.69±1.97 mg/dl and 109.6±3.92 mg/dl, respectively. Also, the liver markers were positively affected by AeLE. In conclusion, A. echioides leaf extract was found to reduce hyperglycemia and significantly improve the biochemical profile of the mice.


Subject(s)
Andrographis , Blood Glucose/drug effects , Diabetes Mellitus, Experimental/drug therapy , Hypoglycemic Agents/pharmacology , Plant Extracts/pharmacology , Alanine Transaminase/blood , Andrographis/chemistry , Animals , Aspartate Aminotransferases/blood , Biomarkers/blood , Blood Glucose/metabolism , Diabetes Mellitus, Experimental/blood , Diabetes Mellitus, Experimental/etiology , Diet, High-Fat , Hypoglycemic Agents/isolation & purification , Lipids/blood , Male , Metformin/pharmacology , Mice, Inbred C57BL , Plant Extracts/isolation & purification , Plant Leaves
3.
Phys Chem Chem Phys ; 19(41): 28116-28126, 2017 Oct 25.
Article in English | MEDLINE | ID: mdl-29019484

ABSTRACT

Double-doped skutterudite Co4Sb12 compounds are reported as a good n-type thermoelectric system which operate in the mid-temperature range. Instead of filling the skutterudite phase to minimize the thermal conductivity, it is proposed to induce disorder in the pnicogen rings by the substitution of Zn/Cd/Sn and Se. Structural analyses of the prepared compounds were carried out by Rietveld refinement process. The compounds show overall reduction in thermal conductivity, particularly the lattice part. Since vibration modes of heat-carrying phonons predominantly fall within the frequency range of the pnicogen rings, double substitutions on those pnicogen rings are particularly helpful in distracting the thermal transport. As larger mass difference and strain fluctuations can more efficiently scatter the heat-carrying phonons through short mean free path, it drastically restrains the thermal transport of the compounds, and this effect has been successfully demonstrated using the Debye-Callaway-Klemens model. Smooth electrical transport behavior is observed in all the samples and the power factor values are quite comparable to reported values. Phonon scattering mechanism and local distortion in the structure of the compounds is also evaluated by Raman analysis. Collectively, a high peak ZT of ∼0.7 and ∼0.65 at 673 K is obtained for Co4Sb11.86Se0.1Zn0.04 and Co4Sb11.86Se0.1Sn0.04 compounds which shows more than 50% enhancement relative to the pristine Co4Sb12 system.

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