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1.
Clinical targeting of HIV capsid protein with a long-acting small molecule.
Nature
; 584(7822): 614-618, 2020 08.
Article
in English
| MEDLINE | ID: mdl-32612233
2.
Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes.
Antimicrob Agents Chemother
; 65(5)2023 05 01.
Article
in English
| MEDLINE | ID: mdl-33649107
3.
Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection.
Antimicrob Agents Chemother
; 67(1): e0134822, 2023 01 24.
Article
in English
| MEDLINE | ID: mdl-36519892
4.
Human pharmacokinetics prediction with an in vitro-in vivo correction factor approach and in vitro drug-drug interaction profile of bictegravir, a potent integrase-strand transfer inhibitor component in approved biktarvy® for the treatment of HIV-1 infection.
Xenobiotica
; 52(12): 1020-1030, 2022 Dec.
Article
in English
| MEDLINE | ID: mdl-36701274
5.
Antiviral Activity of Bictegravir (GS-9883), a Novel Potent HIV-1 Integrase Strand Transfer Inhibitor with an Improved Resistance Profile.
Antimicrob Agents Chemother
; 60(12): 7086-7097, 2016 12.
Article
in English
| MEDLINE | ID: mdl-27645238
6.
A small-molecule inhibitor of hepatitis C virus infectivity.
Antimicrob Agents Chemother
; 58(1): 386-96, 2014.
Article
in English
| MEDLINE | ID: mdl-24165192
7.
Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase.
Antimicrob Agents Chemother
; 57(2): 804-10, 2013 Feb.
Article
in English
| MEDLINE | ID: mdl-23183437
8.
Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therapy.
PLoS One
; 17(4): e0262516, 2022.
Article
in English
| MEDLINE | ID: mdl-35363817
9.
Benzothiophene piperazine and piperidine urea inhibitors of fatty acid amide hydrolase (FAAH).
Bioorg Med Chem Lett
; 19(10): 2865-9, 2009 May 15.
Article
in English
| MEDLINE | ID: mdl-19386497
10.
Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection.
J Med Chem
; 57(5): 1893-901, 2014 Mar 13.
Article
in English
| MEDLINE | ID: mdl-24144213
11.
Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.
ACS Med Chem Lett
; 2(2): 91-96, 2011 Feb 10.
Article
in English
| MEDLINE | ID: mdl-21666860
12.
Optimization of Pharmacokinetics through Manipulation of Physicochemical Properties in a Series of HCV Inhibitors.
ACS Med Chem Lett
; 2(10): 715-9, 2011 Oct 13.
Article
in English
| MEDLINE | ID: mdl-24900257
13.
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain.
Chem Biol
; 16(4): 411-20, 2009 Apr 24.
Article
in English
| MEDLINE | ID: mdl-19389627
14.
Bio-orthogonal affinity purification of direct kinase substrates.
J Am Chem Soc
; 127(15): 5288-9, 2005 Apr 20.
Article
in English
| MEDLINE | ID: mdl-15826144
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