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1.
Nature ; 617(7962): 717-723, 2023 05.
Article in English | MEDLINE | ID: mdl-37225883

ABSTRACT

Flexible solar cells have a lot of market potential for application in photovoltaics integrated into buildings and wearable electronics because they are lightweight, shockproof and self-powered. Silicon solar cells have been successfully used in large power plants. However, despite the efforts made for more than 50 years, there has been no notable progress in the development of flexible silicon solar cells because of their rigidity1-4. Here we provide a strategy for fabricating large-scale, foldable silicon wafers and manufacturing flexible solar cells. A textured crystalline silicon wafer always starts to crack at the sharp channels between surface pyramids in the marginal region of the wafer. This fact enabled us to improve the flexibility of silicon wafers by blunting the pyramidal structure in the marginal regions. This edge-blunting technique enables commercial production of large-scale (>240 cm2), high-efficiency (>24%) silicon solar cells that can be rolled similarly to a sheet of paper. The cells retain 100% of their power conversion efficiency after 1,000 side-to-side bending cycles. After being assembled into large (>10,000 cm2) flexible modules, these cells retain 99.62% of their power after thermal cycling between -70 °C and 85 °C for 120 h. Furthermore, they retain 96.03% of their power after 20 min of exposure to air flow when attached to a soft gasbag, which models wind blowing during a violent storm.

2.
Small ; 20(21): e2308553, 2024 May.
Article in English | MEDLINE | ID: mdl-38100299

ABSTRACT

Monolithic perovskite/silicon tandem solar cells have been attracted much attention in recent years. Despite their high performances, the stability issue of perovskite-based devices is recognized as one of the key challenges to realize industrial application. When comes to the perovskite top subcell, the interface between perovskite and electron transporting layers (usually C60) significantly affects the device efficiency as well as the stability due to their poor adhesion. Here, different from the conventional interfacial passivation using metal fluorides, a hybrid intermediate layer is proposed-PMMA functionalized with ionic liquid (IL)-is introduced at the perovskite/C60 interface. The application of PMMA essentially improves the interfacial stability due to its strong hydrophobicity, while adding IL relieves the charge accumulation between PMMA and the perovskite. Thus, an optimal wide-bandgap perovskite solar cells achieves power conversion efficiency of 20.62%. These cells are further integrated as top subcells with silicon bottom cells in a monolithic tandem structure, presenting an optimized PCE up to 27.51%. More importantly, such monolithic perovskite/silicon cells exhibit superior stability by maintaining 90% of initial efficiency after 1200 h under continuous illumination.

3.
Cardiovasc Diabetol ; 23(1): 3, 2024 01 03.
Article in English | MEDLINE | ID: mdl-38172813

ABSTRACT

BACKGROUND: The triglyceride-glucose (TyG) index has been proposed as a surrogate marker of insulin resistance. However, the relationship between the TyG index and central blood pressure (BP), has not been well studied in adults. METHODS: A total of 715 Chinese adult participants were enrolled in this study. Anthropometric and BP were assessed. The TyG index was calculated as ln[fasting triglycerides(mg/dL) × fasting glucose(mg/dL)/2]. Central BP was measured using SphygmoCor system. RESULTS: The participants were stratified into three groups based on the TyG index, and significant differences were observed in metabolic and cardiovascular parameters and the prevalence of hypertension among the groups. Both brachial (ß = 1.38, P = 0.0310; group highest vs. lowest, ß = 2.66, P = 0.0084) and aortic (ß = 2.38, P = 0.0002; group highest vs. lowest, ß = 3.96, P = 0.0001) diastolic BP were significantly and independently associated with the TyG index and increasing TyG index tertile. However, there was no independent association between the TyG index and systolic BP. A one-unit increase in the TyG index was associated with a 46% higher risk of hypertension (P = 0.0121), and compared with the lowest group, participants in the highest group had a 95% higher risk of hypertension (P = 0.0057). CONCLUSIONS: Our study demonstrates a significant and independent association between the TyG index and both brachial and aortic diastolic BP in Chinese adults. Furthermore, the TyG index was found to be an independent predictor of hypertension.


Subject(s)
Hypertension , Insulin Resistance , Adult , Humans , Glucose/metabolism , Blood Glucose/metabolism , Triglycerides , Blood Pressure , Hypertension/diagnosis , Hypertension/epidemiology , Biomarkers , China/epidemiology , Risk Factors
4.
Phys Rev Lett ; 129(4): 049901, 2022 Jul 22.
Article in English | MEDLINE | ID: mdl-35939036

ABSTRACT

This corrects the article DOI: 10.1103/PhysRevLett.127.176401.

5.
Phys Rev Lett ; 127(12): 127205, 2021 Sep 17.
Article in English | MEDLINE | ID: mdl-34597084

ABSTRACT

We study the effect of Dzyaloshinskii-Moriya (DM) interaction on the triangular lattice U(1) quantum spin liquid (QSL) which is stabilized by ring-exchange interactions. A weak DM interaction introduces a staggered flux to the U(1) QSL state and changes the density of states at the spinon Fermi surface. If the DM vector contains in-plane components, then the spinons gain nonzero Berry phase. The resultant thermal conductances κ_{xx} and κ_{xy} qualitatively agree with the experimental results on the material EtMe_{3}Sb[Pd(dmit)_{2}]_{2}. Furthermore, owing to perfect nesting of the Fermi surface, a spin density wave state is triggered by larger DM interactions. On the other hand, when the ring-exchange interaction decreases, another antiferromagnetic (AFM) phase with 120° order shows up which is proximate to a U(1) Dirac QSL. We discuss the difference of the two AFM phases from their static structure factors and excitation spectra.

6.
Phys Rev Lett ; 127(17): 176401, 2021 Oct 22.
Article in English | MEDLINE | ID: mdl-34739291

ABSTRACT

Multifold degenerate fermions have attracted a lot of research interest in condensed matter physics and materials science, but always lack in two dimensions. In this Letter, from symmetry analysis and lattice model construction, we demonstrate that eightfold degenerate fermions can be realized in two-dimensional systems. In nonmagnetic materials with negligible spin-orbit coupling, the gray magnetic space groups together with SU(2) spin rotation symmetry can protect the two-dimensional eightfold degenerate fermions on a certain high-symmetry axis in the Brillouin zone, no matter whether the system is centrosymmetric or noncentrosymmetric. In antiferromagnetic materials, the eightfold degenerate fermions can also be protected by certain "spin space groups." Furthermore, by first-principles electronic structure calculations, we predict that the paramagnetic phase of the monolayer LaB_{8} on a suitable substrate is a two-dimensional eightfold degenerate as well as Dirac node-line semimetal. Especially, the eightfold degenerate points are close to the Fermi level, which makes monolayer LaB_{8} a good platform to study the exotic physical properties of two-dimensional eightfold degenerate fermions.

7.
Phys Rev Lett ; 123(19): 197201, 2019 Nov 08.
Article in English | MEDLINE | ID: mdl-31765175

ABSTRACT

In addition to the Kitaev (K) interaction, candidate Kitaev materials also possess Heisenberg (J) and off-diagonal symmetric (Γ) couplings. We investigate the quantum (S=1/2) K-J-Γ model on the honeycomb lattice by a variational Monte Carlo method. In addition to the "generic" Kitaev spin liquid (KSL), we find that there is just one proximate KSL (PKSL) phase, while the rest of the phase diagram contains different magnetically ordered states. The PKSL is a gapless Z_{2} state with 14 Majorana cones, which in contrast to the KSL has a gapless spin response. In a magnetic field applied normal to the honeycomb plane, it realizes two of Kitaev's gapped chiral spin-liquid phases, of which one is non-Abelian with Chern number ν=5 and the other is Abelian with ν=4. These two phases could be distinguished by their thermal Hall conductance.

8.
Phys Rev Lett ; 120(18): 187201, 2018 May 04.
Article in English | MEDLINE | ID: mdl-29775347

ABSTRACT

Motivated by recent experimental observations in α-RuCl_{3}, we study the K-Γ model on the honeycomb lattice in an external magnetic field. By a slave-particle representation and variational Monte Carlo calculations, we reproduce the phase transition from zigzag magnetic order to a field-induced disordered phase. The nature of this state depends crucially on the field orientation. For particular field directions in the honeycomb plane, we find a gapless Dirac spin liquid, in agreement with recent experiments on α-RuCl_{3}. For a range of out-of-plane fields, we predict the existence of a Kalmeyer-Laughlin-type chiral spin liquid, which would show an integer-quantized thermal Hall effect.

9.
Phys Rev Lett ; 119(18): 185701, 2017 Nov 03.
Article in English | MEDLINE | ID: mdl-29219568

ABSTRACT

We discuss the quantum simulation of symmetry-protected topological (SPT) states for interacting fermions in quasi-one-dimensional gases of alkaline-earth-like atoms such as ^{173}Yb. Taking advantage of the separation of orbital and nuclear-spin degrees of freedom in these atoms, we consider Raman-assisted spin-orbit couplings in the clock states, which, together with the spin-exchange interactions in the clock-state manifolds, give rise to SPT states for interacting fermions. We numerically investigate the phase diagram of the system, and study the phase transitions between the SPT phase and the symmetry-breaking phases. The interaction-driven topological phase transition can be probed by measuring local density distribution of the topological edge modes.

10.
Phys Rev Lett ; 119(22): 227208, 2017 Dec 01.
Article in English | MEDLINE | ID: mdl-29286810

ABSTRACT

α-RuCl_{3} is a leading candidate material for the observation of physics related to the Kitaev quantum spin liquid (QSL). By combined susceptibility, specific-heat, and nuclear-magnetic-resonance measurements, we demonstrate that α-RuCl_{3} undergoes a quantum phase transition to a QSL in a magnetic field of 7.5 T applied in the ab plane. We show further that this high-field QSL phase has gapless spin excitations over a field range up to 16 T. This highly unconventional result, unknown in either Heisenberg or Kitaev magnets, offers insight essential to establishing the physics of α-RuCl_{3}.

11.
Phys Chem Chem Phys ; 19(28): 18704-18708, 2017 Jul 19.
Article in English | MEDLINE | ID: mdl-28696438

ABSTRACT

We studied the self-assembly of melem on the Au(111) and Ag(111) surfaces. By scanning tunneling microscopy imaging, we observed two different STM appearances of the melem molecule within the self-assembled nanostructure on Au(111), which resulted from the different intermolecular bonding configurations. Moreover, further DFT details including the intermolecular charge density difference and bonding energy were also obtained to compare the different natures of the intermolecular bonding configurations.

12.
Med Sci Monit ; 22: 3523-3528, 2016 Oct 03.
Article in English | MEDLINE | ID: mdl-27694796

ABSTRACT

BACKGROUND The purpose of this study was to determine the effect of mild hypothermia therapy on gastric mucosa after cardiopulmonary resuscitation (CPR) and the underlying mechanism. MATERIAL AND METHODS Ventricular fibrillation was induced in pigs. After CPR, the surviving pigs were divided into mild hypothermia-treated and control groups. The changes in vital signs and hemodynamic parameters were monitored before cardiac arrest and at intervals of 0.5, 1, 2, 4, 6, 12, and 24 h after restoration of spontaneous circulation. Serum IL-6 was determined at the same time, and gastroscopy was performed. The pathologic changes were noted, and the expression of IL-6 was determined by hematoxylin and eosin (HE) staining and immunohistochemistry under light. RESULTS The heart rate, mean arterial blood pressure, and cardiac output in both groups did not differ significantly. The gastric mucosa ulcer index evaluated by gastroscopy 2 h and 24 h after restoration of spontaneous circulation (ROSC) in the mild hypothermic group was lower than that the control group (P<0.05). The inflammatory pathologic score of gastric mucosa in the mild hypothermic group 6-24 h after ROSC was lower than that in the control group (P<0.05). Serum and gastric mucosa IL-6 expression 0.5-4 h and 6, 12, and 24 h after ROSC was lower in the mild hypothermic group than in the control group (P<0.05). CONCLUSIONS Mild hypothermia treatment protects gastric mucosa after ROSC via inhibiting IL-6 production and relieving the inflammatory reaction.


Subject(s)
Cardiopulmonary Resuscitation/methods , Gastric Mucosa/physiology , Hypothermia, Induced/methods , Interleukin-6/antagonists & inhibitors , Ventricular Fibrillation/therapy , Animals , Arterial Pressure/physiology , Cardiac Output/physiology , Disease Models, Animal , Heart Arrest/therapy , Heart Rate/physiology , Hemodynamics , Interleukin-6/metabolism , Male , Random Allocation , Swine , Swine, Miniature , Ventricular Fibrillation/physiopathology
13.
Chin J Traumatol ; 19(6): 348-352, 2016 Dec 01.
Article in English | MEDLINE | ID: mdl-28088940

ABSTRACT

PURPOSE: To describe an indirect reduction technique during minimally invasive percutaneous plate osteosynthesis (MIPPO) of tibial shaft fractures with the use of a distraction support. METHODS: Between March 2011 and October 2014, 52 patients with a mean age of 48 years (16-72 years) sustaining tibial shaft fractures were included. All the patients underwent MIPPO for the fractures using a distraction support prior to insertion of the plate. Fracture angular deformity was assessed by goni- ometer measurement on preoperative and postoperative images. RESULTS: Preoperative radiographs revealed a mean of 7.6°(1.2°-28°) angulation in coronal plane and a mean of 6.8°(0.5°-19°) angulation in sagittal plane. Postoperative anteroposterior and lateral radio- graphs showed a mean of 0.8°(0°-4.0°) and 0.6°(0°-3.6°) of varus/valgus and apex anterior/posterior angulation, respectively. No intraoperative or postoperative complications were noted. CONCLUSIONS: This study suggests that the distraction support during MIPPO of tibial shaft fractures is an effective and safe method with no associated complications.


Subject(s)
Bone Plates , Fracture Fixation, Internal/methods , Minimally Invasive Surgical Procedures/methods , Tibial Fractures/surgery , Adolescent , Adult , Aged , Fracture Fixation, Internal/adverse effects , Humans , Middle Aged
14.
Phys Rev Lett ; 113(26): 267206, 2014 Dec 31.
Article in English | MEDLINE | ID: mdl-25615382

ABSTRACT

It is well known that a bosonic Mott insulator can be realized by condensing vortices of a boson condensate. Usually, a vortex becomes an antivortex (and vice versa) under time reversal symmetry, and the condensation of vortices results in a trivial Mott insulator. However, if each vortex or antivortex interacts with a spin trapped at its core, the time reversal transformation of the composite vortex operator will contain an extra minus sign. It turns out that such a composite vortex condensed state is a bosonic topological insulator (BTI) with gapless boundary excitations protected by U(1)⋊Z2(T) symmetry. We point out that in BTI, an external π-flux monodromy defect carries a Kramers doublet. We propose lattice model Hamiltonians to realize the BTI phase, which might be implemented in cold atom systems or spin-1 solid state systems.

15.
Nutrients ; 16(11)2024 May 24.
Article in English | MEDLINE | ID: mdl-38892531

ABSTRACT

Propolis has potential anti-inflammatory properties, but little is known about its efficacy against inflammatory reactions caused by drug-resistant bacteria, and the difference in efficacy between propolis and tree gum is also unclear. Here, an in vivo study was performed to study the effects of ethanol extract from poplar propolis (EEP) and poplar tree gum (EEG) against heat-inactivated methicillin-resistant Staphylococcus aureus (MRSA)-induced acute lung injury (ALI) in mice. Pre-treatment with EEP and EEG (100 mg/kg, p.o.) resulted in significant protective effects on ALI in mice, and EEP exerted stronger activity to alleviate lung tissue lesions and ALI scores compared with that of EEG. Furthermore, EEP significantly suppressed the levels of pro-inflammatory mediators in the lung, including TNF-α, IL-1ß, IL-6, and IFN-γ. Gut microbiota analysis revealed that both EEP and EEG could modulate the composition of the gut microbiota, enhance the abundance of beneficial microbiota and reduce the harmful ones, and partly restore the levels of short-chain fatty acids. EEP could modulate more serum metabolites and showed a more robust correlation between serum metabolites and gut microbiota. Overall, these results support the anti-inflammatory effects of propolis in the treatment of ALI, and the necessity of the quality control of propolis.


Subject(s)
Acute Lung Injury , Gastrointestinal Microbiome , Inflammation Mediators , Methicillin-Resistant Staphylococcus aureus , Propolis , Propolis/pharmacology , Animals , Methicillin-Resistant Staphylococcus aureus/drug effects , Acute Lung Injury/microbiology , Acute Lung Injury/drug therapy , Gastrointestinal Microbiome/drug effects , Mice , Male , Inflammation Mediators/blood , Inflammation Mediators/metabolism , Anti-Inflammatory Agents/pharmacology , Staphylococcal Infections/drug therapy , Cytokines/blood , Cytokines/metabolism , Hot Temperature , Disease Models, Animal
16.
Clin Neurol Neurosurg ; 240: 108283, 2024 05.
Article in English | MEDLINE | ID: mdl-38608350

ABSTRACT

OBJECTIVES: The relationship between cognitive function and frailty in moyamoya disease (MMD) remains unclear, and the underlying mechanism is poorly understood. This study aims to investigate whether white matter hyperintensities (WMHs) mediate the association between frailty and cognitive impairment in MMD. METHODS: Patients with MMD were consecutively enrolled in our study from January 2021 to May 2023. Pre-admission frailty and cognition were assessed using the Clinical Frailty Scale (CFS) and cognitive tests, respectively. Regional deep WMH (DWMH) and periventricular WMH (PWMH) volumes were calculated using the Brain Anatomical Analysis using Diffeomorphic deformation toolbox based on SPM 12 software. Multivariate logistic regression analysis was conducted to evaluate the association between frailty and cognitive function in MMD. Mediation analysis was performed to assess whether WMHs explained the association between frailty and cognition. RESULTS: A total of 85 patients with MMD were enrolled in this study. On the basis of the CFS scores, 24 patients were classified as frail, 38 as pre-frail, and 23 as robust. Significant differences were observed in learning, memory, processing speed, executive functions, and semantic memory among the three groups (p < 0.001). Frailty was independently associated with memory and executive functions (p < 0.05); even after controlling for WMH. Mediation analysis indicated that the associations of frailty with memory and executive functions were partially mediated by WMH, DWMH, and PWMH (p < 0.05). CONCLUSION: Frailty is significantly correlated with a higher risk of cognitive impairment in MMD, even after adjusting for other covariates. WMHs partially mediate the association between frailty and cognitive impairment.


Subject(s)
Cognitive Dysfunction , Frailty , Moyamoya Disease , White Matter , Humans , Male , Female , Cognitive Dysfunction/etiology , Moyamoya Disease/complications , Moyamoya Disease/diagnostic imaging , White Matter/diagnostic imaging , White Matter/pathology , Frailty/complications , Frailty/diagnostic imaging , Middle Aged , Adult , Magnetic Resonance Imaging , Neuropsychological Tests
17.
Cureus ; 16(3): e55682, 2024 Mar.
Article in English | MEDLINE | ID: mdl-38586713

ABSTRACT

Objective This population-based cross-sectional study aimed to investigate the association between thyroid hormones and renal function in euthyroid Chinese individuals, as the relationship between thyroid hormones and renal function in this population remains unclear. Methods A total of 661 participants were included in the study after excluding individuals with thyroid diseases, incomplete clinical measurements, or those taking medications affecting thyroid function. Participants were categorized into three groups based on serum thyroid hormone and antibody levels. The study adjusted for covariates and assessed the glomerular filtration rate (GFR) and urine albumin-to-creatinine ratio (ACR) in relation to thyroid hormone levels. Results After adjusting for covariates, the study found a significant increase in GFR in the middle and highest tertiles of free triiodothyronine (FT3) and the highest tertile of total triiodothyronine (TT3). Serum FT3 and TT3 levels were significantly associated with GFR. Additionally, the study observed a significantly lower GFR in the highest tertile of thyroid-stimulating hormone (TSH) compared to the lowest tertile. However, thyroid hormone and antibody levels were not associated with the ACR. Furthermore, the highest tertiles of TT3 and total thyroxine (TT4) were associated with a decreased risk of chronic kidney disease (CKD). Conclusion In our study among euthyroid Chinese individuals, we observed a significant association between thyroid function and GFR. Specifically, lower FT3, TT3, and higher TSH were associated with reduced GFR, indicating a potential role for thyroid hormones in maintaining renal function. Furthermore, lower levels of TT3 and TT4 were associated with an increased risk of CKD. These findings suggest a direct link between thyroid and renal function, even in euthyroid individuals, emphasizing the need for further investigation to elucidate the underlying mechanisms and potential therapeutic implications.

18.
Phys Rev Lett ; 110(6): 067205, 2013 Feb 08.
Article in English | MEDLINE | ID: mdl-23432300

ABSTRACT

Symmetry-protected topological (SPT) states are short-range entangled states with symmetry. Nontrivial SPT states have symmetry-protected gapless edge excitations. In 2 dimension (2D), there are an infinite number of nontrivial SPT phases with SU(2) or SO(3) symmetry. These phases can be described by SU(2) or SO(3) nonlinear-sigma models with a quantized topological θ term. At an open boundary, the θ term becomes the Wess-Zumino-Witten term and consequently the boundary excitations are decoupled gapless left movers and right movers. Only the left movers (if θ>0) carry the SU(2) or SO(3) quantum numbers. As a result, the SU(2) SPT phases have a half-integer quantized spin Hall conductance and the SO(3) SPT phases have an even-integer quantized spin Hall conductance. Both the SU(2) and SO(3) SPT phases are symmetric under their U(1) subgroup and can be viewed as U(1) SPT phases with even-integer quantized Hall conductance.

19.
Phys Rev Lett ; 110(7): 076401, 2013 Feb 15.
Article in English | MEDLINE | ID: mdl-25166386

ABSTRACT

We propose to observe and manipulate topological edge spins in a one-dimensional optical lattice based on currently available experimental platforms. Coupling the atomic spin states to a laser-induced periodic Zeeman field, the lattice system can be driven into a symmetry protected topological (SPT) phase, which belongs to the chiral unitary (AIII) class protected by particle number conservation and chiral symmetries. In the free-fermion case the SPT phase is classified by a Z invariant which reduces to Z(4) with interactions. The zero edge modes of the SPT phase are spin polarized, with left and right edge spins polarized to opposite directions and forming a topological spin qubit (TSQ). We demonstrate a novel scheme to manipulate the zero modes and realize single spin control in an optical lattice. The manipulation of TSQs has potential applications to quantum computation.

20.
Int J Mol Sci ; 14(6): 11994-2003, 2013 Jun 05.
Article in English | MEDLINE | ID: mdl-23739677

ABSTRACT

The main objective of this work was to study the unique polymorphisms of the lactate dehydrogenase-1 (LDH1) gene in yak (Bos grunniens). Native polyacrylamide gel electrophoresis revealed three phenotypes of LDH1 (a tetramer of H subunit) in yak heart and longissimus muscle extracts. The corresponding gene, ldhb, encoding H subunits of three LDH1 phenotypes was obtained by RT-PCR. A total of six nucleotide differences were detected in yak ldhb compared with that of cattle, of which five mutations cause amino acid substitutions. Sequence analysis shows that the G896A and C689A, mutations of ldhb gene, result in alterations of differently charged amino acids, and create the three phenotypes (F, M, and S) of yak LDH1. Molecular modeling of the H subunit of LDH indicates that the substituted amino acids are not located within NAD+ or substrate binding sites. PCR-RFLP examination of G896A mutation demonstrated that most LDH1-F samples are actually heterozygote at this site. These results help to elucidate the molecular basis and genetic characteristic of the three unique LDH1 phenotypes in yak.


Subject(s)
Cattle/genetics , L-Lactate Dehydrogenase/genetics , Polymorphism, Genetic , Alleles , Animals , Breeding , Cloning, Molecular , DNA, Complementary/genetics , Electrophoresis, Polyacrylamide Gel , Gene Frequency/genetics , Genotype , Isoelectric Point , Isoenzymes/chemistry , Isoenzymes/genetics , Isoenzymes/metabolism , L-Lactate Dehydrogenase/chemistry , L-Lactate Dehydrogenase/metabolism , Models, Molecular , Molecular Sequence Data , Molecular Weight , Phenotype , Polymerase Chain Reaction , Polymorphism, Restriction Fragment Length , Protein Subunits/genetics , Sequence Analysis, DNA , Static Electricity
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