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1.
Fitoterapia ; 78(3): 171-4, 2007 Apr.
Article in English | MEDLINE | ID: mdl-17275209

ABSTRACT

The anti-diarrheal activity of methanol extract of dried bark and aerial parts of Litsea polyantha (MELP) has been evaluated in mice using different models (castor oil-induced diarrhea and propulsive gut motility in mice). MELP (50, 75, 100 mg/kg, p.o.) significantly (P<0.01) reduced the onset of diarrhea, fecal excretion and also showed a significant (P<0.001) reduction in gastrointestinal motility on charcoal meal test in mice. The results of the study support the folklore use of the plant for diarrheal remedies.


Subject(s)
Antidiarrheals/pharmacology , Diarrhea/prevention & control , Gastrointestinal Motility/drug effects , Litsea , Phytotherapy , Plant Extracts/pharmacology , Administration, Oral , Animals , Antidiarrheals/administration & dosage , Antidiarrheals/therapeutic use , Castor Oil , Diarrhea/chemically induced , Dose-Response Relationship, Drug , Female , Male , Mice , Plant Bark , Plant Components, Aerial , Plant Extracts/administration & dosage , Plant Extracts/therapeutic use
3.
Science ; 225(4667): 1140, 1984 Sep 14.
Article in English | MEDLINE | ID: mdl-17782415
5.
Can Med Assoc J ; 117(4): 313, 316-7, 1977 Aug 20.
Article in English | MEDLINE | ID: mdl-329969
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