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1.

Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.

Banskota, Samagya; Raguram, Aditya; Suh, Susie; Du, Samuel W; Davis, Jessie R; Choi, Elliot H; Wang, Xiao; Nielsen, Sarah C; Newby, Gregory A; Randolph, Peyton B; Osborn, Mark J; Musunuru, Kiran; Palczewski, Krzysztof; Liu, David R.

Cell ; 185(2): 250-265.e16, 2022 01 20.

Article in English | MEDLINE | ID: mdl-35021064

2.

Active learning-based STEM education for in-person and online learning.

Sandrone, Stefano; Scott, Gregory; Anderson, William J; Musunuru, Kiran.

Cell ; 184(6): 1409-1414, 2021 03 18.

Article in English | MEDLINE | ID: mdl-33740446

3.

Genetics of Common, Complex Coronary Artery Disease.

Musunuru, Kiran; Kathiresan, Sekar.

Cell ; 177(1): 132-145, 2019 03 21.

Article in English | MEDLINE | ID: mdl-30901535

4.

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

Musunuru, Kiran; Chadwick, Alexandra C; Mizoguchi, Taiji; Garcia, Sara P; DeNizio, Jamie E; Reiss, Caroline W; Wang, Kui; Iyer, Sowmya; Dutta, Chaitali; Clendaniel, Victoria; Amaonye, Michael; Beach, Aaron; Berth, Kathleen; Biswas, Souvik; Braun, Maurine C; Chen, Huei-Mei; Colace, Thomas V; Ganey, John D; Gangopadhyay, Soumyashree A; Garrity, Ryan; Kasiewicz, Lisa N; Lavoie, Jennifer; Madsen, James A; Matsumoto, Yuri; Mazzola, Anne Marie; Nasrullah, Yusuf S; Nneji, Joseph; Ren, Huilan; Sanjeev, Athul; Shay, Madeleine; Stahley, Mary R; Fan, Steven H Y; Tam, Ying K; Gaudelli, Nicole M; Ciaramella, Giuseppe; Stolz, Leslie E; Malyala, Padma; Cheng, Christopher J; Rajeev, Kallanthottathil G; Rohde, Ellen; Bellinger, Andrew M; Kathiresan, Sekar.

Nature ; 593(7859): 429-434, 2021 05.

Article in English | MEDLINE | ID: mdl-34012082

5.

Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need.

Brooks, Dominique L; Whittaker, Madelynn N; Qu, Ping; Musunuru, Kiran; Ahrens-Nicklas, Rebecca C; Wang, Xiao.

Am J Hum Genet ; 110(12): 2003-2014, 2023 Dec 07.

Article in English | MEDLINE | ID: mdl-37924808

6.

Stem cell models of cardiac development and disease.

Musunuru, Kiran; Domian, Ibrahim J; Chien, Kenneth R.

Annu Rev Cell Dev Biol ; 26: 667-87, 2010.

Article in English | MEDLINE | ID: mdl-20604707

7.

Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition.

Musunuru, Kiran.

Annu Rev Med ; 72: 447-458, 2021 01 27.

Article in English | MEDLINE | ID: mdl-33234004

8.

An Overview of Genome Editing in Cardiovascular and Metabolic Diseases.

Musunuru, Kiran.

Adv Exp Med Biol ; 1396: 3-16, 2023.

Article in English | MEDLINE | ID: mdl-36454456

9.

Therapeutic application of genome editing in dyslipidemia.

Whittaker, Madelynn N; Musunuru, Kiran.

Curr Opin Lipidol ; 33(2): 133-138, 2022 04 01.

Article in English | MEDLINE | ID: mdl-34907967

10.

A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.

Sakamoto, Tomoya; Matsuura, Timothy R; Wan, Shibiao; Ryba, David M; Kim, J Unil; Won, Kyoung Jae; Lai, Ling; Petucci, Christopher; Petrenko, Nataliya; Musunuru, Kiran; Vega, Rick B; Kelly, Daniel P.

Circ Res ; 126(12): 1685-1702, 2020 06 05.

Article in English | MEDLINE | ID: mdl-32212902

11.

Translating research into therapies.

Glimcher, Laurie H; Lindvall, Olle; Aguirre, Vince; Topalian, Suzanne L; Musunuru, Kiran; Fauci, Anthony S.

Cell ; 148(6): 1077-8, 2012 Mar 16.

Article in English | MEDLINE | ID: mdl-22532970

12.

Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.

Patel, Nirav; Russell, Griffin K; Musunuru, Kiran; Gutierrez, Orlando M; Halade, Ganesh; Kain, Vasundhara; Lv, Wenjian; Prabhu, Sumanth D; Margulies, Kenneth B; Cappola, Thomas P; Arora, Garima; Wang, Thomas J; Arora, Pankaj.

Circ Res ; 125(11): 957-968, 2019 11 08.

Article in English | MEDLINE | ID: mdl-31588864

13.

Human Germline Genome Editing.

Ormond, Kelly E; Mortlock, Douglas P; Scholes, Derek T; Bombard, Yvonne; Brody, Lawrence C; Faucett, W Andrew; Garrison, Nanibaa' A; Hercher, Laura; Isasi, Rosario; Middleton, Anna; Musunuru, Kiran; Shriner, Daniel; Virani, Alice; Young, Caroline E.

Am J Hum Genet ; 101(2): 167-176, 2017 Aug 03.

Article in English | MEDLINE | ID: mdl-28777929

14.

Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells.

Peters, Derek T; Henderson, Christopher A; Warren, Curtis R; Friesen, Max; Xia, Fang; Becker, Caroline E; Musunuru, Kiran; Cowan, Chad A.

Development ; 143(9): 1475-81, 2016 05 01.

Article in English | MEDLINE | ID: mdl-27143754

15.

CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia.

Chadwick, Alexandra C; Musunuru, Kiran.

Arterioscler Thromb Vasc Biol ; 38(1): 12-18, 2018 01.

Article in English | MEDLINE | ID: mdl-28838920

16.

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.

Wang, Xiao; Raghavan, Avanthi; Peters, Derek T; Pashos, Evanthia E; Rader, Daniel J; Musunuru, Kiran.

Arterioscler Thromb Vasc Biol ; 38(1): 76-82, 2018 01.

Article in English | MEDLINE | ID: mdl-29097363

17.

Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.

Whittaker, Madelynn N; Testa, Lauren C; Quigley, Aidan; Jindal, Ishaan; Cortez-Alvarado, Saúl V; Qu, Ping; Yang, Yifan; Alameh, Mohamad-Gabriel; Musunuru, Kiran; Wang, Xiao.

Arterioscler Thromb Vasc Biol ; 43(10): 2075-2077, 2023 10.

Article in English | MEDLINE | ID: mdl-37589141

18.

From Hypertrophy to Heart Failure: What Is New in Genetic Cardiomyopathies.

Reza, Nosheen; Musunuru, Kiran; Owens, Anjali Tiku.

Curr Heart Fail Rep ; 16(5): 157-167, 2019 10.

Article in English | MEDLINE | ID: mdl-31243690

19.

Stem cell modeling of lipid genetics.

Musunuru, Kiran.

Curr Opin Lipidol ; 29(2): 151-155, 2018 04.

Article in English | MEDLINE | ID: mdl-29351105

20.

Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis.

Musunuru, Kiran; Kathiresan, Sekar.

Circ Res ; 118(4): 579-85, 2016 Feb 19.

Article in English | MEDLINE | ID: mdl-26892959

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Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins.

Active learning-based STEM education for in-person and online learning.

Genetics of Common, Complex Coronary Artery Disease.

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

Efficient in vivo prime editing corrects the most frequent phenylketonuria variant, associated with high unmet medical need.

Stem cell models of cardiac development and disease.

Treating Coronary Artery Disease: Beyond Statins, Ezetimibe, and PCSK9 Inhibition.

An Overview of Genome Editing in Cardiovascular and Metabolic Diseases.

Therapeutic application of genome editing in dyslipidemia.

A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.

Translating research into therapies.

Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.

Human Germline Genome Editing.

Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells.

CRISPR-Cas9 Genome Editing for Treatment of Atherogenic Dyslipidemia.

Interrogation of the Atherosclerosis-Associated SORT1 (Sortilin 1) Locus With Primary Human Hepatocytes, Induced Pluripotent Stem Cell-Hepatocytes, and Locus-Humanized Mice.

Epigenome Editing Durability Varies Widely Across Cardiovascular Disease Target Genes.

From Hypertrophy to Heart Failure: What Is New in Genetic Cardiomyopathies.

Stem cell modeling of lipid genetics.

Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis.