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1.
J Pediatr Hematol Oncol ; 36(7): e426-9, 2014 Oct.
Article in English | MEDLINE | ID: mdl-24072244

ABSTRACT

Inflammatory myofibroblastic tumors are rare lesions of uncertain etiology that are often difficult to diagnose because of their myriad clinical presentations. Not uncommon, they mimic persistent pneumonia. We report a 4-year-old girl who presented with prolonged pyrexia, weight loss, severe anemia, hepatosplenomegaly, and nonresolving pneumonia. Initial investigations including flexible bronchoscopy and bronchial washing for usual causes of persistent pneumonia, such as tuberculosis and other infections, were negative. Chest computed tomography revealed a well-defined lesion involving the lingula and left upper lobe with extension into the subpleural space. Pleural tap and biopsy was also noncontributory. Thoracoscopic biopsy was suggestive of an inflammatory myofibroblastic tumor. As the lesion was encasing the major vessels, it was considered inoperable. The patient did not respond to steroid therapy and etoricoxib and later succumbed to the illness. This uncommon tumor should be considered in the differential diagnosis of children who presented with unresolving consolidation with pyrexia.


Subject(s)
Inflammation/diagnosis , Neoplasms, Muscle Tissue/diagnosis , Pneumonia/diagnosis , Tuberculosis, Pulmonary/diagnosis , Bronchoscopy , Child, Preschool , Diagnosis, Differential , Fatal Outcome , Female , Fever/diagnosis , Humans
2.
Indian J Radiol Imaging ; 24(2): 121-4, 2014 Apr.
Article in English | MEDLINE | ID: mdl-25024518

ABSTRACT

We present the case of a 10-month-old boy with multisystem Langerhans cell histiocytosis showing thin-walled lung cysts along with computed tomography (CT) evidence of persistent pulmonary interstitial emphysema (PPIE), in the absence of pneumothorax or pneumomediastinum. Follow-up CT performed after 6 months demonstrated complete resolution of interstitial emphysema.

3.
Indian J Med Paediatr Oncol ; 33(4): 242-9, 2012 Oct.
Article in English | MEDLINE | ID: mdl-23580829

ABSTRACT

Wilms' tumor (WT) is the most common abdominal tumor in children. Many pediatric renal tumors in the past were categorized as WT; however, in recent years, several specific renal tumors have been recognized as distinct pathological entities. The age and clinical presentation of the child and distinctive imaging features may help in reaching a specific diagnosis in most cases. This is important as it has implications on the pre-operative diagnostic work-up and prognosis of the child. However, it is often not possible to differentiate one from the other pediatric renal tumor on the basis of imaging alone, and the final diagnosis is often made at histological examination of the surgical specimen. This article reviews the imaging features of primary malignant renal neoplasms in children along with their clinical presentation and pathological features.

4.
Jpn J Radiol ; 30(6): 480-5, 2012 Jul.
Article in English | MEDLINE | ID: mdl-22488612

ABSTRACT

The imaging features of xanthogranulomatous cholecystitis closely resemble those of gallbladder carcinoma, especially those of the wall-thickening variety. There is an overlap between these two conditions with respect to the clinical features and certain imaging findings. However, certain finer details like the presence of intramural hypoattenuating nodules and the type of mucosal enhancement may help to differentiate these two conditions. In this article, we have highlighted some of these imaging features. The importance of making an accurate diagnosis lies in the significant difference between the prognosis and the surgical management of the two disease entities.


Subject(s)
Cholecystitis/diagnostic imaging , Gallbladder Neoplasms/diagnostic imaging , Granuloma/diagnostic imaging , Tomography, X-Ray Computed/methods , Xanthomatosis/diagnostic imaging , Adult , Aged , Cholecystography/methods , Diagnosis, Differential , Female , Gallbladder/diagnostic imaging , Humans , Male , Middle Aged , Ultrasonography
5.
Jpn J Radiol ; 30(10): 858-62, 2012 Dec.
Article in English | MEDLINE | ID: mdl-22986751

ABSTRACT

Recurrent small-bowel volvulus is a state of recurrent intermittent or long-standing persistent twisting of small-bowel loops around its mesentery. The association of mesenteric cysts with recurrent small-bowel volvulus as the cause or effect is a much debated issue in the literature. We report two cases of mesenteric lymphangioma and one case of enteric duplication cyst seen in association with recurrent small-bowel volvulus of long duration in absence of malrotation.


Subject(s)
Intestinal Volvulus/diagnosis , Jejunum/pathology , Lymphangioma, Cystic/diagnosis , Mesenteric Cyst/diagnosis , Peritoneal Neoplasms/diagnosis , Child , Child, Preschool , Humans , Infant , Intestinal Volvulus/complications , Intestinal Volvulus/surgery , Lymphangioma, Cystic/complications , Lymphangioma, Cystic/surgery , Male , Mesenteric Cyst/complications , Mesenteric Cyst/surgery , Peritoneal Neoplasms/complications , Peritoneal Neoplasms/surgery , Tomography, X-Ray Computed , Treatment Outcome , Ultrasonography, Doppler, Color
6.
Indian J Endocrinol Metab ; 15(1): 51-3, 2011 Jan.
Article in English | MEDLINE | ID: mdl-21584169

ABSTRACT

Total fat replacement of the pancreas is rare. Focal fatty replacement is the most common degenerative lesion of pancreas. Focal fatty deposits have no major clinical significance; however, extreme fat replacement is of pathologic significance, as it is associated with marked reduction in exocrine function of pancreas, resulting in malabsorption due to pancreatic enzyme insufficiency.

7.
Indian J Radiol Imaging ; 20(1): 6-10, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20351984

ABSTRACT

Tuberculosis of the orbit is rare, even in places where tuberculosis is endemic. The disease may involve soft tissue, the lacrimal gland, or the periosteum or bones of the orbital wall. Intracranial extension, in the form of extradural abscess, and infratemporal fossa extension has been described. This pictorial essay illustrates the imaging findings of nine histopathologically confirmed cases of orbital tuberculosis. All these patients responded to antituberculous treatment.

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