Search | Nursing VHL Search Portal

1.

A Biobank of Breast Cancer Explants with Preserved Intra-tumor Heterogeneity to Screen Anticancer Compounds.

Bruna, Alejandra; Rueda, Oscar M; Greenwood, Wendy; Batra, Ankita Sati; Callari, Maurizio; Batra, Rajbir Nath; Pogrebniak, Katherine; Sandoval, Jose; Cassidy, John W; Tufegdzic-Vidakovic, Ana; Sammut, Stephen-John; Jones, Linda; Provenzano, Elena; Baird, Richard; Eirew, Peter; Hadfield, James; Eldridge, Matthew; McLaren-Douglas, Anne; Barthorpe, Andrew; Lightfoot, Howard; O'Connor, Mark J; Gray, Joe; Cortes, Javier; Baselga, Jose; Marangoni, Elisabetta; Welm, Alana L; Aparicio, Samuel; Serra, Violeta; Garnett, Mathew J; Caldas, Carlos.

Cell ; 167(1): 260-274.e22, 2016 09 22.

Article in English | MEDLINE | ID: mdl-27641504

2.

A Pilot Trial of Continuous Glucose Monitoring Upon Emergency Department Discharge Among People With Diabetes Mellitus.

O'Connor, Mark J; Ding, Xinyi; Hernandez, Camila; Hubacz, Lisa; Church, Richard J; O'Connor, Laurel.

Endocr Pract ; 30(2): 122-127, 2024 Feb.

Article in English | MEDLINE | ID: mdl-37952581

3.

Mechanisms of PARP Inhibitor Resistance.

O'Connor, Mark J; Forment, Josep V.

Cancer Treat Res ; 186: 25-42, 2023.

Article in English | MEDLINE | ID: mdl-37978129

4.

Targeting the DNA Damage Response in Cancer.

O'Connor, Mark J.

Mol Cell ; 60(4): 547-60, 2015 Nov 19.

Article in English | MEDLINE | ID: mdl-26590714

5.

Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress.

Lloyd, Rebecca L; Urban, Vaclav; Muñoz-Martínez, Francisco; Ayestaran, Iñigo; Thomas, John C; de Renty, Christelle; O'Connor, Mark J; Forment, Josep V; Galanty, Yaron; Jackson, Stephen P.

Nucleic Acids Res ; 49(15): 8665-8683, 2021 09 07.

Article in English | MEDLINE | ID: mdl-34329458

6.

Olaparib increases the therapeutic index of hemithoracic irradiation compared with hemithoracic irradiation alone in a mouse lung cancer model.

Jiang, Yanyan; Martin, Jennifer; Alkadhimi, Maryam; Shigemori, Kay; Kinchesh, Paul; Gilchrist, Stuart; Kersemans, Veerle; Smart, Sean; Thompson, James M; Hill, Mark A; O'Connor, Mark J; Davies, Barry R; Ryan, Anderson J.

Br J Cancer ; 124(11): 1809-1819, 2021 05.

Article in English | MEDLINE | ID: mdl-33742147

7.

SLFN11 informs on standard of care and novel treatments in a wide range of cancer models.

Winkler, Claudia; Armenia, Joshua; Jones, Gemma N; Tobalina, Luis; Sale, Matthew J; Petreus, Tudor; Baird, Tarrion; Serra, Violeta; Wang, Anderson T; Lau, Alan; Garnett, Mathew J; Jaaks, Patricia; Coker, Elizabeth A; Pierce, Andrew J; O'Connor, Mark J; Leo, Elisabetta.

Br J Cancer ; 124(5): 951-962, 2021 03.

Article in English | MEDLINE | ID: mdl-33339894

8.

Differential therapeutic effects of PARP and ATR inhibition combined with radiotherapy in the treatment of subcutaneous versus orthotopic lung tumour models.

Tran Chau, Vanessa; Liu, Winchygn; Gerbé de Thoré, Marine; Meziani, Lydia; Mondini, Michele; O'Connor, Mark J; Deutsch, Eric; Clémenson, Céline.

Br J Cancer ; 123(5): 762-771, 2020 09.

Article in English | MEDLINE | ID: mdl-32546832

9.

Klinefelter Syndrome and Diabetes.

O'Connor, Mark J; Snyder, Emma A; Hayes, Frances J.

Curr Diab Rep ; 19(9): 71, 2019 07 31.

Article in English | MEDLINE | ID: mdl-31367971

10.

Characteristics of Patients with Recurrent Emergency Medical Services Utilization for Symptomatic Hypoglycemia in an Urban Setting.

O'Connor, Laurel; Kue, Ricky C; O'Connor, Mark J.

Prehosp Emerg Care ; 23(6): 780-787, 2019.

Article in English | MEDLINE | ID: mdl-30893563

11.

Outcomes of Prehospital Chemical Sedation With Ketamine Versus Haloperidol and Benzodiazepine or Physical Restraint Only.

O'Connor, Laurel; Rebesco, Matthew; Robinson, Conor; Gross, Karen; Castellana, Andrew; O'Connor, Mark J; Restuccia, Marc.

Prehosp Emerg Care ; 23(2): 201-209, 2019.

Article in English | MEDLINE | ID: mdl-30118360

12.

Candidate biomarkers of PARP inhibitor sensitivity in ovarian cancer beyond the BRCA genes.

Hodgson, Darren R; Dougherty, Brian A; Lai, Zhongwu; Fielding, Anitra; Grinsted, Lynda; Spencer, Stuart; O'Connor, Mark J; Ho, Tony W; Robertson, Jane D; Lanchbury, Jerry S; Timms, Kirsten M; Gutin, Alexander; Orr, Maria; Jones, Helen; Gilks, Blake; Womack, Chris; Gourley, Charlie; Ledermann, Jonathan; Barrett, J Carl.

Br J Cancer ; 119(11): 1401-1409, 2018 11.

Article in English | MEDLINE | ID: mdl-30353044

13.

Anti-tumor activity of the ATR inhibitor AZD6738 in HER2 positive breast cancer cells.

Kim, Hee-Jun; Min, Ahrum; Im, Seock-Ah; Jang, Hyemin; Lee, Kyung Hun; Lau, Alan; Lee, Miso; Kim, Seongyeong; Yang, Yaewon; Kim, Jungeun; Kim, Tae Yong; Oh, Do-Youn; Brown, Jeffrey; O'Connor, Mark J; Bang, Yung-Jue.

Int J Cancer ; 140(1): 109-119, 2017 Jan 01.

Article in English | MEDLINE | ID: mdl-27501113

14.

Forest clearfelling effects on dissolved oxygen and metabolism in peatland streams.

O'Driscoll, Connie; O'Connor, Mark; Asam, Zaki-Ul-Zaman; de Eyto, Elvira; Brown, Lee E; Xiao, Liwen.

J Environ Manage ; 166: 250-9, 2016 Jan 15.

Article in English | MEDLINE | ID: mdl-26513323

15.

Systolic and diastolic mechanics in stress cardiomyopathy.

Medeiros, Keith; O'Connor, Mark J; Baicu, Catalin F; Fitzgibbons, Timothy P; Shaw, Peter; Tighe, Dennis A; Zile, Michael R; Aurigemma, Gerard P.

Circulation ; 129(16): 1659-67, 2014 Apr 22.

Article in English | MEDLINE | ID: mdl-24503950

16.

Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (SAHA), enhances anti-tumor effects of the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib in triple-negative breast cancer cells.

Min, Ahrum; Im, Seock-Ah; Kim, Debora Keunyoung; Song, Sang-Hyun; Kim, Hee-Jun; Lee, Kyung-Hun; Kim, Tae-Yong; Han, Sae-Won; Oh, Do-Youn; Kim, Tae-You; O'Connor, Mark J; Bang, Yung-Jue.

Breast Cancer Res ; 17: 33, 2015 Mar 07.

Article in English | MEDLINE | ID: mdl-25888415

17.

Mild hyperthermia inhibits homologous recombination, induces BRCA2 degradation, and sensitizes cancer cells to poly (ADP-ribose) polymerase-1 inhibition.

Krawczyk, Przemek M; Eppink, Berina; Essers, Jeroen; Stap, Jan; Rodermond, Hans; Odijk, Hanny; Zelensky, Alex; van Bree, Chris; Stalpers, Lukas J; Buist, Marrije R; Soullié, Thomas; Rens, Joost; Verhagen, Hence J M; O'Connor, Mark J; Franken, Nicolaas A P; Ten Hagen, Timo L M; Kanaar, Roland; Aten, Jacob A.

Proc Natl Acad Sci U S A ; 108(24): 9851-6, 2011 Jun 14.

Article in English | MEDLINE | ID: mdl-21555554

18.

Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.

Staniszewska, Anna D; Pilger, Domenic; Gill, Sonja J; Jamal, Kunzah; Bohin, Natacha; Guzzetti, Sofia; Gordon, Jacob; Hamm, Gregory; Mundin, Gill; Illuzzi, Giuditta; Pike, Andy; McWilliams, Lisa; Maglennon, Gareth; Rose, Jonathan; Hawthorne, Glen; Cortes Gonzalez, Miguel; Halldin, Christer; Johnström, Peter; Schou, Magnus; Critchlow, Susan E; Fawell, Stephen; Johannes, Jeffrey W; Leo, Elisabetta; Davies, Barry R; Cosulich, Sabina; Sarkaria, Jann N; O'Connor, Mark J; Hamerlik, Petra.

Clin Cancer Res ; 30(7): 1338-1351, 2024 Apr 01.

Article in English | MEDLINE | ID: mdl-37967136

19.

Large-scale Pan-cancer Cell Line Screening Identifies Actionable and Effective Drug Combinations.

Bashi, Azadeh C; Coker, Elizabeth A; Bulusu, Krishna C; Jaaks, Patricia; Crafter, Claire; Lightfoot, Howard; Milo, Marta; McCarten, Katrina; Jenkins, David F; van der Meer, Dieudonne; Lynch, James T; Barthorpe, Syd; Andersen, Courtney L; Barry, Simon T; Beck, Alexandra; Cidado, Justin; Gordon, Jacob A; Hall, Caitlin; Hall, James; Mali, Iman; Mironenko, Tatiana; Mongeon, Kevin; Morris, James; Richardson, Laura; Smith, Paul D; Tavana, Omid; Tolley, Charlotte; Thomas, Frances; Willis, Brandon S; Yang, Wanjuan; O'Connor, Mark J; McDermott, Ultan; Critchlow, Susan E; Drew, Lisa; Fawell, Stephen E; Mettetal, Jerome T; Garnett, Mathew J.

Cancer Discov ; 14(5): 846-865, 2024 May 01.

Article in English | MEDLINE | ID: mdl-38456804

20.

Concordance of ATM (ataxia telangiectasia mutated) immunohistochemistry between biopsy or metastatic tumor samples and primary tumors in gastric cancer patients.

Kim, Hee Sung; Kim, Min A; Hodgson, Darren; Harbron, Christopher; Wellings, Robert; O'Connor, Mark J; Womack, Christopher; Yin, Xiaolu; Bang, Yung-Jue; Im, Seok-Ah; Lee, Byung Lan; Kim, Woo Ho.

Pathobiology ; 80(3): 127-37, 2013.

Article in English | MEDLINE | ID: mdl-23328638

Nursing VHL Search Portal

Information and Knowledge for Health

Config filters

Your selection (0)

Export format:

Export: