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1.
J Labelled Comp Radiopharm ; 56(9-10): 471-4, 2013.
Article in English | MEDLINE | ID: mdl-24285523

ABSTRACT

The preparation of [(14) C]tribendimidine, a broad-spectrum anthelmintic agent related to amidantel, and its use during excretion and metabolism studies in the rat are described in this paper.


Subject(s)
Anthelmintics/chemistry , Phenylenediamines/chemistry , Animals , Anthelmintics/metabolism , Carbon Radioisotopes/chemistry , Isotope Labeling , Male , Phenylenediamines/metabolism , Rats , Rats, Sprague-Dawley
2.
Steroids ; 73(7): 760-4, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18423505

ABSTRACT

The synthesis of exemestane Aromasin, an irreversible steroidal aromatase inhibitor, specifically labelled with (13)C is reported. The preparation of [(13)C(3)]exemestane was achieved according to an eight-step procedure starting from the commercially available testosterone.


Subject(s)
Androstadienes/chemical synthesis , Carbon Isotopes , Isotope Labeling/methods , Androstadienes/chemistry , Androstadienes/isolation & purification , Testosterone/chemistry
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