Search details
1.
A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies.
Invest New Drugs
; 34(2): 184-92, 2016 Apr.
Article
in English
| MEDLINE | ID: mdl-26792581
2.
Genetic depletion and pharmacological targeting of αv integrin in breast cancer cells impairs metastasis in zebrafish and mouse xenograft models.
Breast Cancer Res
; 17: 28, 2015 Feb 25.
Article
in English
| MEDLINE | ID: mdl-25849225
3.
A 24-Week, Phase IIa, Randomized, Double-Blind, Placebo-Controlled Study of Ziritaxestat in Early Diffuse Cutaneous Systemic Sclerosis.
Arthritis Rheumatol
; 75(8): 1434-1444, 2023 08.
Article
in English
| MEDLINE | ID: mdl-36787101
4.
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases.
J Med Chem
; 64(19): 14557-14586, 2021 10 14.
Article
in English
| MEDLINE | ID: mdl-34581584
5.
The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis.
J Clin Med
; 9(4)2020 Apr 16.
Article
in English
| MEDLINE | ID: mdl-32316235
6.
Antitumorigenic Effects of Inhibiting Ephrin Receptor Kinase Signaling by GLPG1790 against Colorectal Cancer Cell Lines In Vitro and In Vivo.
J Oncol
; 2020: 9342732, 2020.
Article
in English
| MEDLINE | ID: mdl-32184826
7.
Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases.
Cancer Res
; 67(12): 5821-30, 2007 Jun 15.
Article
in English
| MEDLINE | ID: mdl-17575150
8.
The Small Molecule Ephrin Receptor Inhibitor, GLPG1790, Reduces Renewal Capabilities of Cancer Stem Cells, Showing Anti-Tumour Efficacy on Preclinical Glioblastoma Models.
Cancers (Basel)
; 11(3)2019 Mar 13.
Article
in English
| MEDLINE | ID: mdl-30871240
9.
A convenient clinically relevant model of human breast cancer bone metastasis.
Clin Exp Metastasis
; 25(1): 33-42, 2008.
Article
in English
| MEDLINE | ID: mdl-17902030
10.
Ezrin regulates E-cadherin-dependent adherens junction assembly through Rac1 activation.
Mol Biol Cell
; 14(5): 2181-91, 2003 May.
Article
in English
| MEDLINE | ID: mdl-12802084
11.
Pharmacological targeting of the ephrin receptor kinase signalling by GLPG1790 in vitro and in vivo reverts oncophenotype, induces myogenic differentiation and radiosensitizes embryonal rhabdomyosarcoma cells.
J Hematol Oncol
; 10(1): 161, 2017 10 06.
Article
in English
| MEDLINE | ID: mdl-28985758
12.
Targeting of α(v)-integrins in stem/progenitor cells and supportive microenvironment impairs bone metastasis in human prostate cancer.
Neoplasia
; 13(6): 516-25, 2011 Jun.
Article
in English
| MEDLINE | ID: mdl-21677875
13.
A multiparameter approach to monitor disease activity in collagen-induced arthritis.
Arthritis Res Ther
; 12(4): R160, 2010.
Article
in English
| MEDLINE | ID: mdl-20731827
Results
1 -
13
de 13
1
Next >
>>